Huperzine a as potential treatment of Alzheimer's disease: An assessment on chemistry, pharmacology, and clinical studies

Chemistry and Biodiversity

Volumn 8, Issue 7, 2011, Pages 1189-1204

  Ha, Giang T ^a   Wong, Ryan K ^a   Zhang, Yan ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

Alzheimer's disease; Biological activity; Dementia; Huperzine A; Pharmacokinetics; Toxicity

Indexed keywords

ACETYLCHOLINESTERASE; ALPHA TOCOPHEROL; CHOLINESTERASE INHIBITOR; DONEPEZIL; HUPERZINE A; PHYSOSTIGMINE; PLACEBO; RIVASTIGMINE; TACRINE;

ACUPUNCTURE; ALZHEIMER DISEASE; ANKLE EDEMA; ANOREXIA; ANTICHOLINERGIC SYNDROME; AREA UNDER THE CURVE; COGNITION; CONSTIPATION; DIZZINESS; DROWSINESS; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG ELIMINATION; DRUG HALF LIFE; DRUG INDUCED HEADACHE; DRUG MECHANISM; DRUG MEGADOSE; DRUG SYNTHESIS; ENZYME INHIBITION; GASTROINTESTINAL SYMPTOM; HEART RATE; HUMAN; HYPERTENSION; INSOMNIA; MAXIMUM PLASMA CONCENTRATION; MEMORY; MULTICENTER STUDY (TOPIC); NAUSEA; NEUROPROTECTION; NONHUMAN; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SIDE EFFECT; TACHYCARDIA; TIME TO MAXIMUM PLASMA CONCENTRATION; TREATMENT OUTCOME; UNSPECIFIED SIDE EFFECT; VOMITING; XEROSTOMIA;

ALKALOIDS; ALZHEIMER DISEASE; ANIMALS; CHOLINESTERASE INHIBITORS; CLINICAL TRIALS AS TOPIC; HUMANS; NEUROPROTECTIVE AGENTS; SESQUITERPENES;

ANIMALIA;

EID: 79960600801     PISSN: 16121872     EISSN: 16121880     Source Type: Journal    
DOI: 10.1002/cbdv.201000269     Document Type: Review

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