Pharmacokinetics and tissue distribution study of scoparone in rats by ultraperformance liquid-chromatography with tandem high-definition mass spectrometry

Fitoterapia

Volumn 83, Issue 4, 2012, Pages 795-800

  Yin, Quanwei ^a   Sun, Hui ^a   Zhang, Aihua ^a   Wang, Xijun ^a  

^a HEILONGJIANG UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Pharmacokinetics; Rats; Scoparone; Tissue distribution; UPLC MS MS

Indexed keywords

ACETONITRILE; FORMIC ACID; SCOPARONE;

ACCURACY; ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTEMISIA ANNUA; ARTICLE; BLOOD BRAIN BARRIER; CHINESE HERB; DISTRIBUTION VOLUME; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; ELUTION; IN VIVO STUDY; KIDNEY; LIVER; MALE; NONHUMAN; PRECIPITATION; PRIORITY JOURNAL; RAT; SENSITIVITY AND SPECIFICITY; SEPARATION TECHNIQUE; SPLEEN; TANDEM HIGH DEFINITION MASS SPECTROMETRY; TANDEM MASS SPECTROMETRY; TISSUE DISTRIBUTION; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

ADMINISTRATION, ORAL; ANIMALS; ARTEMISIA; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COUMARINS; LIVER DISEASES; MALE; RATS; RATS, WISTAR; TANDEM MASS SPECTROMETRY; TISSUE DISTRIBUTION;

ARTEMISIA ANNUA; RATTUS;

EID: 84861660878     PISSN: 0367326X     EISSN: 18736971     Source Type: Journal    
DOI: 10.1016/j.fitote.2012.03.010     Document Type: Article

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