Comparative pharmacokinetics of baicalin in plasma after oral administration of Huang-Lian-Jie-Du-Tang or pure baicalin in MCAO and sham-operated rats

Fitoterapia

Volumn 81, Issue 6, 2010, Pages 490-496

  Zeng, Ming Fei ^a   Pan, Lin Mei ^a   Zhu, Hua Xu ^a   Zhang, Qi Chun ^a   Guo, Li Wei ^a  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Baicalin; HLJDT decoction; MCAO; Pharmacokinetics

Indexed keywords

BAICALIN; CHINESE DRUG; HUANG LIAN JIE DU TANG; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG HALF LIFE; MALE; MAXIMUM PLASMA CONCENTRATION; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; PRIORITY JOURNAL; RAT;

ADMINISTRATION, ORAL; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUGS, CHINESE HERBAL; FLAVONOIDS; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS;

EID: 77955712558     PISSN: 0367326X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fitote.2010.01.004     Document Type: Article

References (32)

1. S. Meairs, N. Wahlgren, U. Dirnagl, O. Lindvall, and P. Rothwell Stroke research priorities for the next decade - a representative view of the European scientific community Cerebrovasc Dis 22 2006 75
2. T. Itoh Application of Oren-gedoku-to to many illnesses in Japanese oriental medicine Kampo Newest Therapy 10 2001 243 in Japanese
3. C. Chen, N. Venketasubramanian, R.N. Gan, and C. Lambert Danqi Piantang Jiaonang (DJ), a Traditional Chinese Medicine, in Poststroke Recovery Stroke 40 2009 859
4. K. Kawashima, N. Haruo, and K. Kogure Effect of Oren-gedoku-to on cerebral vascular accident Pharma Medica 6 1988 33
5. Y. Ohta, T. Kobayashi, K. Nishida, E. Sasaki, and I. Ishiguro Preventive effect of Oren-gedoku-to (Huanglian-Jie -Du-Tang) extract on the development of stress-induced acute gastric mucosal lesions in rats J Ethnopharmacol 67 1999 377
6. Y.S. Hwang, C.Y. Shin, Y. Huh, and J.H. Ryu Hwangryun-Hae-Dok-tang (Huanglian-Jie-Du-Tang) extract and its constituents reduce ischemia-reperfusion brain injury and neutrophil infiltration in rats Life Sci 71 2002 2105
7. M. Fujiwara, and K. Iwasaki Toki-Shakuyaku-San and Oren-Gedoku-To improve the disruption of spatial cognition induced by cerebral ischaemia and central cholinergic dysfunction in rats Phytotherapy Res 7 1993 S60
8. J. Xu, Y. Murakami, K. Matsumoto, M. Tohda, H. Watanabe, S. Zhang, Q. Yu, and J. Shen Protective effect of Oren-gedoku-to (Huang-Lian-Jie-Du-Tang) against impairment of learning and memory induced by transient cerebral ischemia in mice J Ethnopharmacol 73 2000 405
9. Y. Ohta, M. Kongo-Nishimura, T. Hayashi, and T. Kishikawa Effect of Oren-gedoku-to (Huanglian-Jie-Du-Tang) extract on disruption of hepatic antioxidant defense systems in rats treated with d-galactosamin J Ethnopharmacol 94 2004 323
10. P.G. Xiao, and C.X. Liu Pharmacology, pharmacokinetics and toxicology of Chinese traditional medicine for stroke therapy Asian J Drug Metabol Pharmacokinet 2 2005 83
11. Y. Yu, Y.J. Yang, and Y.G. Tao Effect of baicalin and dexamethasone on cytokines in brain tissue of infectious brain edema Bull Human Med Univ 25 2000 519
12. Y.J. Yang, C.Y. Zhu, and X. Chen The protective effects of baicalin on pertussis bacilli-induced brain edema in rats Natl Med J China 78 1998 630
13. W.T. Chang, Z.H. Shao, J.J. Yin, and S. Mehendale Comparative effects of flavonoids on oxidant scavenging and ischemia-reperfusion injury in cardiomyocytes Eur J Pharmacol 566 2007 58
14. P.Z.X.M. Liu, J.Y. Wang, Q. Li, Z.Y. Wang, and F.Y. Xu Protective effect of Baicalin on focal cerebral ischemia-reperfusion injury in rats Chin Pharm J 42 2007 743
15. W.H. Li, L.Q. Zhu, S.R. Wang, F.L. Niu, W. Cui, and P.T. Li Effects of Baicalin and gardenoside on oxygen-glucose deprivation and reperfusion injury in neurocytes Chin Pharm J 39 2004 344
16. S.H. Jung, K.D. Kanga, D. Jia, R.J. Fawcetta, R. Safa, T. Kamaldena, and N.N. Osborne The flavonoid baicalin counteracts ischemic and oxidative insults to retinal cell and lipid peroxidation to brain membranes Neurochem Int 53 2008 325
17. Z.J. Zhang, P. Li, Z. Wang, P.T. Li, W.S. Zhang, Z.H. Sun, X.J. Zhang, and Y.Y. Wang A comparative study on the individual and combined effects of baicalin and jasminoidin on focal cerebral ischemia-reperfusion injury Brain Res 1123 2006 188
18. T. Lu, J. Song, F. Huang, Y.X. Deng, X. Lin, G.J. Wang, and D.L. Xiao Comparative pharmacokinetics of baicalin after oral administration of pure baicalin, Radix scutellariae extract and Huang-Lian-Jie-Du-Tang to rats J Ethnopharmacol 110 2007 412
19. Y.H. Kim, D.W. Jeong, Y.C. Kim, D.H. Sohn, E.S. Park, and H.S. Lee Pharmacokinetics of baicalein, baicalin and wogonin after oral administration of a standardized extract of scutellaria baicalensis, PF-2405 in Rats Arch Pharm Res 30 2007 260
20. W.Z. Ju, F. Liu, T. Wu, X.Y. Xia, H.S. Tan, X. Wang, and N.N. Xiong Simultaneous determination of baicalin and chlorogenic acid in human plasma by UPLC-MS/MS Acta Pharmaceutica Sinica 42 2007 1074
21. A. Kotani, S. Kojima, H. Hakamata, and F. Kusu HPLC with electrochemical detection to examine the pharmacokinetics of baicalin and baicalein in rat plasma after oral administration of a Kampo medicine Anal Biochem 350 2006 99
22. V.A. Bhattaram, U. Graefe, C. Kohlert, M. Veit, and H. Derendorf Pharmacokinetics and bioavailability of herbal medicinal products Phytomedicine 9 uppl.3 2002 1
23. C.G. Markgraf, S. Kraydieh, and R. Prado Comparative histopathologic, consequences of photohrombotic occlusion of the distal middle cerebral artery in Sprague-Dawley and Wistary rats Stroke 24 1993 286
24. H. Nagasawa, and K. Kogure Correlation between cererbral blood flow and histologic changes in a new rat model of middle cerebral artery occlusion Stroke 20 1989 1037
25. E.Z. Longa, P.R. Weinstein, S. Carlsion, and R. Cummins Reversible middle cerebral artery occlusion without craniectomy in rats Stroke 20 1989 84
26. H. Wang, J.M. Chen, and Q.M. Zhang High-performance liquid chromatographic determination of baicalin in human plasma J Shenyang Pharm Univ 17 2000 107
27. A. Teruaki, K. Kiyoshi, Y. Erika, I. Kazuhisa, M. Yasuharu, W. Yoko, S. Yoko, and K. Kyoichi Balicalin, the predominant flavone glucuronide of scutellariae radix, is absorbed from the rat gastrointestinal tract as the aglycone and restored to its original form J Pharm Pharmacol 52 2000 1563
28. L. Yi, and X. Xu Study on the precipitation reaction between baicalin and berberine by HPLC J Chromatogr B 810 2004 165
29. Y.X. Deng, C.H. Yang, and L.L. Mou Pharmaokinetic study on baicaln in and wogonoside in diabeticrats in vivo after oral administrating HuanglianJiedu Decoct ion Chinese Tradit and Herb Drug 39 2008 227
30. H. Lu, D.M. Xing, H. Sun, W. Jin, and L.J. Du Pharmacokinetics of puerarin in normal and cerebral ischemia reperfusion rats Chin Pharm J 37 2002 41
31. J.R. Li, X.S. Gao, N. Lin, J. Zhu, H. Yang, and H. Yi Effects of coptis root alone and its combination with Scutellaria root on the osmotic fragility of rat erythrocytes in vitro Zhong Guo Shi Yan Fang Ji Xue Za Zhi 52 1999 31
32. N. Lin, X.S. Gao, J.R. Li, and J. Zhu Influence of huanglian used in combination with huangqin and gancao on the erythrocytic osmotic fragilitas of experimental glucose-6-phosphate dehydrogenase (G6PD) deficiency in rats China J Chinese Mater Med 23 1998 630