HSF4 is involved in DNA damage repair through regulation of Rad51

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1822, Issue 8, 2012, Pages 1308-1315

  Cui, Xiukun ^a   Zhang, Jing ^a,b   Du, Rong ^a   Wang, Lei ^a   Archacki, Stephen ^c   Zhang, Yuexuan ^a   Yuan, Mingxiong ^a   Ke, Tie ^a   Li, Hui ^a   Li, Duanzhuo ^a   Li, Chang ^a   Li, David Wan Cheng ^d   Tang, Zhaohui ^a   Yin, Zhan ^a,b   Liu, Mugen ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b INSTITUTE OF HYDROBIOLOGY   (China)

^c LERNER RESEARCH INSTITUTE   (United States)

^d UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Camptothecin; Cataract; DNA damage; HSF4; Rad51

Indexed keywords

CAMPTOTHECIN; HEAT SHOCK FACTOR 4 PROTEIN; HEAT SHOCK PROTEIN; NUCLEIC ACID BINDING PROTEIN; RAD51 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CATARACT; DNA DAMAGE; DNA REPAIR; DNA STRAND BREAKAGE; GENE CONTROL; GENE SILENCING; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; ZEBRA FISH;

ANIMALS; CAMPTOTHECIN; CATARACT; CELL DIFFERENTIATION; CELL LINE; DNA DAMAGE; DNA REPAIR; DNA-BINDING PROTEINS; GENE KNOCKDOWN TECHNIQUES; HEAT-SHOCK PROTEINS; HUMANS; LENS, CRYSTALLINE; PROMOTER REGIONS, GENETIC; RAD51 RECOMBINASE; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION; ZEBRAFISH;

DANIO RERIO;

EID: 84861630497     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2012.05.005     Document Type: Article

References (37)

1. Zhang Y., Ouyang S., Zhang L., Tang X., Song Z., Liu P. Oxygen-induced changes in mitochondrial DNA and DNA repair enzymes in aging rat lens. Mech. Ageing Dev. 2010, 131:666-673.
2. Ates O., Alp H.H., Kocer I., Baykal O., Salman I.A. Oxidative DNA damage in patients with cataract. Acta Ophthalmol. 2010, 88:891-895.
3. Sorte K., Sune P., Bhake A., Shivkumar V.B., Gangane N., Basak A. Quantitative assessment of DNA damage directly in lens epithelial cells from senile cataract patients. Mol. Vis. 2011, 17:1-6.
4. Marsili S., Salganik R.I., Albright C.D., Freel C.D., Johnsen S., Peiffer R.L., Costello M.J. Cataract formation in a strain of rats selected for high oxidative stress. Exp. Eye Res. 2004, 79:595-612.
5. Padma G., Mamata M., Reddy K.R., Padma T. Polymorphisms in two DNA repair genes (XPD and XRCC1)-association with age related cataracts. Mol. Vis. 2011, 17:127-133.
6. Unal M., Guven M., Batar B., Ozaydin A., Sarici A., Devranoglu K. Polymorphisms of DNA repair genes XPD and XRCC1 and risk of cataract development. Exp. Eye Res. 2007, 85:328-334.
7. Sung P., Klein H. Mechanism of homologous recombination: mediators and helicases take on regulatory functions. Nat. Rev. Mol. Cell Biol. 2006, 7:739-750.
8. San F.J., Sung P., Klein H. Mechanism of eukaryotic homologous recombination. Annu. Rev. Biochem. 2008, 77:229-257.
9. Kinner A., Wu W., Staudt C., Iliakis G. Gamma-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin. Nucleic Acids Res. 2008, 36:5678-5694.
10. Schild D., Wiese C. Overexpression of RAD51 suppresses recombination defects: a possible mechanism to reverse genomic instability. Nucleic Acids Res. 2010, 38:1061-1070.
11. Golding S.E., Rosenberg E., Neill S., Dent P., Povirk L.F., Valerie K. Extracellular signal-related kinase positively regulates ataxia telangiectasia mutated, homologous recombination repair, and the DNA damage response. Cancer Res. 2007, 67:1046-1053.
12. Hu Y., Mivechi N.F. Association and regulation of heat shock transcription factor 4b with both extracellular signal-regulated kinase mitogen-activated protein kinase and dual-specificity tyrosine phosphatase DUSP26. Mol. Cell. Biol. 2006, 26:3282-3294.
13. Yang Y.G., Frappart P.O., Frappart L., Wang Z.Q., Tong W.M. A novel function of DNA repair molecule Nbs1 in terminal differentiation of the lens fibre cells and cataractogenesis. DNA Repair (Amst) 2006, 5:885-893.
14. Kobayashi J., Antoccia A., Tauchi H., Matsuura S., Komatsu K. NBS1 and its functional role in the DNA damage response. DNA Repair (Amst) 2004, 3:855-861.
15. Wu C.Y., Lin C.T., Wu M.Z., Wu K.J. Induction of HSPA4 and HSPA14 by NBS1 overexpression contributes to NBS1-induced in vitro metastatic and transformation activity. J. Biomed. Sci. 2011, 18:1.
16. Ke T., Wang Q.K., Ji B., Wang X., Liu P., Zhang X., Tang Z., Ren X., Liu M. Novel HSF4 mutation causes congenital total white cataract in a Chinese family. Am. J. Ophthalmol. 2006, 142:298-303.
17. Bu L., Jin Y., Shi Y., Chu R., Ban A., Eiberg H., Andres L., Jiang H., Zheng G., Qian M., Cui B., Xia Y., Liu J., Hu L., Zhao G., Hayden M.R., Kong X. Mutant DNA-binding domain of HSF4 is associated with autosomal dominant lamellar and Marner cataract. Nat. Genet. 2002, 31:276-278.
18. Min J.N., Zhang Y., Moskophidis D., Mivechi N.F. Unique contribution of heat shock transcription factor 4 in ocular lens development and fiber cell differentiation. Genesis 2004, 40:205-217.
19. Fujimoto M., Izu H., Seki K., Fukuda K., Nishida T., Yamada S., Kato K., Yonemura S., Inouye S., Nakai A. HSF4 is required for normal cell growth and differentiation during mouse lens development. EMBO J. 2004, 23:4297-4306.
20. Tsuzuki T., Fujii Y., Sakumi K., Tominaga Y., Nakao K., Sekiguchi M., Matsushiro A., Yoshimura Y. MoritaT, Targeted disruption of the Rad51 gene leads to lethality in embryonic mice. Proc. Natl. Acad. Sci. U. S. A. 1996, 93:6236-6240.
21. Sonoda E., Sasaki M.S., Buerstedde J.M., Bezzubova O., Shinohara A., Ogawa H., Takata M., Yamaguchi-Iwai Y., Takeda S. Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death. EMBO J. 1998, 17:598-608.
22. Barbano R., Copetti M., Perrone G., Pazienza V., Muscarella L.A., Balsamo T., Storlazzi C.T., Ripoli M., Rinaldi M., Valori V.M., Latiano T.P., Maiello E., Stanziale P., Carella M., Mangia A., Pellegrini F., Bisceglia M., Muda A.O., Altomare V., Murgo R., Fazio V.M., Parrella P. High RAD51 mRNA expression characterize estrogen receptor-positive/progesteron receptor-negative breast cancer and is associated with patient's outcome. Int. J. Cancer 2011, 129:536-545.
23. Yoshikawa K., Ogawa T., Baer R., Hemmi H., Honda K., Yamauchi A., Inamoto T., Ko K., Yazumi S., Motoda H., Kodama H., Noguchi S., Gazdar A.F., Yamaoka Y., Takahashi R. Abnormal expression of BRCA1 and BRCA1-interactive DNA-repair proteins in breast carcinomas. Int. J. Cancer 2000, 88:28-36.
24. Xiang H., Wang J., Mao Y., Liu M., Reddy V.N., Li D.W. Human telomerase accelerates growth of lens epithelial cells through regulation of the genes mediating RB/E2F pathway. Oncogene 2002, 21:3784-3791.
25. Yan Q., Gong L., Deng M., Zhang L., Sun S., Liu J., Ma H., Yuan D., Chen P.C., Hu X., Liu J., Qin J., Xiao L., Huang X.Q., Zhang J., Li D.W. Sumoylation activates the transcriptional activity of Pax-6, an important transcription factor for eye and brain development. Proc. Natl. Acad. Sci. U. S. A. 2010, 107:21034-21039.
26. Turchi L., Fareh M., Aberdam E., Kitajima S., Simpson F., Wicking C., Aberdam D., Virolle T. ATF3 and p15PAF are novel gatekeepers of genomic integrity upon UV stress. Cell Death Differ. 2009, 16:728-737.
27. Fujimoto M., Oshima K., Shinkawa T., Wang B.B., Inouye S., Hayashida N., Takii R., Nakai A. Analysis of HSF4 binding regions reveals its necessity for gene regulation during development and heat shock response in mouse lenses. J. Biol. Chem. 2008, 283:29961-29970.
28. Pommier Y., Barcelo J.M., Rao V.A., Sordet O., Jobson A.G., Thibaut L., Miao Z.H., Seiler J.A., Zhang H., Marchand C., Agama K., Nitiss J.L., Redon C. Repair of topoisomerase I-mediated DNA damage. Prog. Nucleic Acid Res. Mol. Biol. 2006, 81:179-229.
29. Hsiang Y.H., Hertzberg R., Hecht S., Liu L.F. Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. J. Biol. Chem. 1985, 260:14873-14878.
30. Enoki Y., Mukoda Y., Furutani C., Sakurai H. DNA-binding and transcriptional activities of human HSF4 containing mutations that associate with congenital and age-related cataracts. Biochim. Biophys. Acta 2010, 1802:749-753.
31. Sharma S., Hicks J.K., Chute C.L., Brennan J.R., Ahn J.Y., Glover T.W., Canman C.E. REV1 and polymerase zeta facilitate homologous recombination repair. Nucleic Acids Res. 2012, 40:682-691.
32. Oyadomari S., Mori M. Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ. 2004, 11:381-389.
33. Chipitsyna G., Sawaya B.E., Khalili K., Amini S. Cooperativity between Rad51 and C/EBP family transcription factors modulates basal and Tat-induced activation of the HIV-1 LTR in astrocytes. J. Cell. Physiol. 2006, 207:605-613.
34. Mulhern M.L., Madson C.J., Danford A., Ikesugi K., Kador P.F., Shinohara T. The unfolded protein response in lens epithelial cells from galactosemic rat lenses. Invest. Ophthalmol. Vis. Sci. 2006, 47:3951-3959.
35. Azuma N., Hirakiyama A., Inoue T., Asaka A., Yamada M. Mutations of a human homologue of the Drosophila eyes absent gene (EYA1) detected in patients with congenital cataracts and ocular anterior segment anomalies. Hum. Mol. Genet. 2000, 9:363-366.
36. Cook P.J., Ju B.G., Telese F., Wang X., Glass C.K., Rosenfeld M.G. Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions. Nature 2009, 458:591-596.
37. Pommier Y. Camptothecins and topoisomerase I: a foot in the door. Targeting the genome beyond topoisomerase I with camptothecins and novel anticancer drugs: importance of DNA replication, repair and cell cycle checkpoints. Curr. Med. Chem. Anticancer Agents 2004, 4:429-434.