Rendering protein-based particles transiently insoluble for therapeutic applications

Journal of the American Chemical Society

Volumn 134, Issue 21, 2012, Pages 8774-8777

  Xu, Jing ^a   Wang, Jin ^a,c,g   Luft, J Christopher ^a,c   Tian, Shaomin ^a,c   Owens, Gary ^d   Pandya, Ashish A ^a,c   Berglund, Peter ^d   Pohlhaus, Patrick ^d   Maynor, Benjamin W ^d   Smith, Jonathan ^d   Hubby, Bolyn ^d   Napier, Mary E ^a,b,c   Desimone, Joseph M ^a,b,c,e,f  

^a University of North Carolina at Chapel Hill   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

^d Liquidia Technologies Inc   (United States)

^e North Carolina State University   (United States)

^f MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^g BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO GROUP; BOVINE SERUM ALBUMINS; CHEMICAL RESIDUES; CROSSLINKER; GENE DELIVERY; PROTEIN PARTICLES; REDUCING ENVIRONMENT; THERAPEUTIC APPLICATION;

GENE TRANSFER; RNA;

PROTEINS;

BOVINE SERUM ALBUMIN; DISULFIDE; RNA;

AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; CROSS LINKING; DRUG DELIVERY SYSTEM; GENE DELIVERY SYSTEM; PROTEIN CLEAVAGE; RNA REPLICATION; SOLUBILITY;

ANIMALS; CATTLE; CERCOPITHECUS AETHIOPS; CYTOPLASM; DISULFIDES; DRUG CARRIERS; MICROTECHNOLOGY; NANOTECHNOLOGY; PARTICLE SIZE; RNA; SERUM ALBUMIN, BOVINE; SOLUBILITY; TIME FACTORS; VERO CELLS;

EID: 84861624886     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja302363r     Document Type: Article

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