Preparation and validation of a skin model for the evaluation of intradermal powder injection devices

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 81, Issue 2, 2012, Pages 360-368

  Deng, Yibin ^a   Winter, Gerhard ^a   Myschik, Julia ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

Confocal laser scanning microscopy; Epidermal powder immunisation; Indentation behaviour; Mechanical properties; Skin model; Texture analyser

Indexed keywords

AGAR; GELATIN; GLYCEROL; SILICON;

ANIMAL TISSUE; ARTICLE; BIOLOGICAL MODEL; CONFOCAL LASER MICROSCOPY; DISTRIBUTION VOLUME; DRUG DELIVERY SYSTEM; EVALUATION; EXPERIMENTAL PIG; FEMALE; FILM COATING; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; INTRADERMAL POWDER INJECTION DEVICE; MALE; MECHANICS; MOLECULAR STABILITY; NONHUMAN; PARTICLE SIZE; PROCESS DEVELOPMENT; PUNCTURE; ROOM TEMPERATURE; SKIN; SURFACE PROPERTY; VALIDATION STUDY;

ADULT; AGAR; ANIMALS; ANTIGEN-PRESENTING CELLS; EPIDERMIS; GELATIN; HUMANS; HUMIDITY; INJECTIONS, INTRADERMAL; LANGERHANS CELLS; MECHANICAL PHENOMENA; MODELS, BIOLOGICAL; POWDERS; SILICON; SKIN; SWINE; TEMPERATURE; VACCINATION; VACCINES;

EID: 84861618481     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2012.03.008     Document Type: Article

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