Piezoelectric control of needle-free transdermal drug delivery

Journal of Controlled Release

Volumn 124, Issue 1-2, 2007, Pages 88-97

  Stachowiak, Jeanne C ^a   von Muhlen, Marcio G ^b   Li, Thomas H ^a   Jalilian, Laleh ^b   Parekh, Sapun H ^b   Fletcher, Daniel A ^b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b University of California at Berkeley   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Drug delivery; Jet injector; Needle free injector; Piezoelectric; Transdermal

Indexed keywords

DISEASES; FLUID DYNAMICS; NEEDLES; PIEZOELECTRIC ACTUATORS; SPRINGS (COMPONENTS);

JET INJECTOR; NEEDL EFREE INJECTOR;

DRUG DELIVERY;

ARTICLE; DRUG DELIVERY SYSTEM; FLOW RATE; JET INJECTOR; LIQUID; PIEZOELECTRICITY; PRIORITY JOURNAL; SKIN PENETRATION; SYRINGE; TRANSDERMAL DRUG ADMINISTRATION;

DRUG DELIVERY SYSTEMS; ELECTROPORATION; EQUIPMENT DESIGN; INJECTIONS, JET; MODELS, BIOLOGICAL; SKIN;

EID: 36048951795     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2007.08.017     Document Type: Article

References (31)

1. Mitragotri S. Immunization without needles. Nat. Rev., Immunol. 5 12 (2005) 905-916
2. Prausnitz M.R., Mitragotri S., and Langer R. Current status and future potential of transdermal drug delivery. Nat. Rev. Drug Discov. 3 2 (2004) 115-124
3. Wu X.M., Todo H., and Sugibayashi K. Enhancement of skin permeation of high molecular compounds by a combination of microneedle pretreatment and iontophoresis. J. Control. Release 118 2 (2007) 189-195
4. Gill H.S., and Prausnitz M.R. Coated microneedles for transdermal delivery. J. Control. Release 117 2 (2007) 227-237
5. Karande P., Jain A., and Mitragotri S. Insights into synergistic interactions in binary mixtures of chemical permeation enhancers for transdermal drug delivery. J. Control. Release 115 1 (2006) 85-93
6. Baxter J., and Mitragotri S. Jet-induced skin puncture and its impact on needle-free jet injections: experimental studies and a predictive model. J. Control. Release 106 3 (2005) 361-373
7. Baker A.B., and Sanders J.E. Fluid mechanics analysis of a spring-loaded jet injector. IEEE Trans. Biomed. Eng. 46 2 (1999) 235-242
8. Schramm-Baxter J., Katrencik J., and Mitragotri S. Jet injection into polyacrylamide gels: investigation of jet injection mechanics. J. Biomech. 37 8 (2004) 1181-1188
9. Schramm-Baxter J., and Mitragotri S. Needle-free jet injections: dependence of jet penetration and dispersion in the skin on jet power. J. Control. Release 97 3 (2004) 527-535
10. Hoffman P.N., Abuknesha R.A., Andrews N.J., Samuel D., and Lloyd J.S. A model to assess the infection potential of jet injectors used in mass immunisation. Vaccine 19 28-29 (2001) 4020-4027
11. Schramm J., and Mitragotri S. Transdermal drug delivery by jet injectors: energetics of jet formation and penetration. Pharm. Res. 19 11 (2002) 1673-1679
12. Theintz G.E., and Sizonenko P.C. Risks of jet injection of insulin in children. Eur. J. Pediatr. 150 8 (1991) 554-556
13. Mitragotri S. Innovation-current status and future prospects of needle-free liquid jet injectors. Nat. Rev. Drug Discov. 5 7 (2006) 543-548
14. Schneider U., Birnbacher R., and Schober E. Painfulness of needle and jet injection in children with diabetes-mellitus. Eur. J. Pediatr. 153 6 (1994) 409-410
15. Fletcher D.A., and Palanker D.V. Pulsed liquid microjet for microsurgery. Appl. Phys. Lett. 78 13 (2001) 1933-1935
16. Fletcher D.A., et al. Intravascular drug delivery with a pulsed liquid microjet. Arch. Ophthalmol-Chic. 120 9 (2002) 1206-1208
17. Arora A., et al. Needle-free delivery of macromolecules across the skin by nanoliter-volume pulsed microjets. Proc. Natl. Acad. Sci. U. S. A. 104 11 (2007) 4255-4260
18. Bolz R.E., and Tuve G.L. CRC Handbook of Tables for Applied Engineering Science (1973), CRC Press, Boca, Raton, FL
19. Graebel W.P. Engineering Fluid Mechanics (2001), Taylor & Francis, New York, NY
20. Lide D.R. CRC Handbook of Chemistry and Physics (2001), CRC Press, Boca Raton, FL
21. White F.M. Viscous Fluid Flow (2006), McGraw-Hill, New York, NY
22. Goldsmith L.A. Physiology, Biochemistry, and Molecular Biology of the Skin (1991), Oxford University Press, New York, NY
23. Nimni P.c.: M.E., Deguia E., and Bavetta L.A. Collagen hexosamine and tensile strength of rabbit skin during aging. J. Invest. Dermatol. 47 2 (1966) 156-158
24. Holzmann H., Korting G.W., Kobelt D., and Vogel H.G. Studies on mechanical properties of human skin in relation to age and sex. Arch. Klin. Exp. Dermatol. 239 4 (1971) 355-367
25. Vogel H.G. Correlation between tensile-strength and collagen content in rat skin-effect of age and cortisol treatment. Connect Tissue Res. 2 3 (1974) 177-182
26. Vogel H.G. Tensile-strength, relaxation and mechanical recovery in rat skin as influenced by maturation and age. J. Med. 7 2 (1976) 177-188
27. Diridollou S., et al. In vivo model of the mechanical properties of the human skin under suction. Skin Res. Technol. 6 4 (2000) 214-221
28. Papir Y.S., Hsu K.H., and Wildnauer R.H. Mechanical-properties of stratum-corneum. 1. Effect of water and ambient-temperature on tensile properties of newborn rat stratum-corneum. Biochim. Biophys. Acta 399 1 (1975) 170-180
29. Koutroupi K.S., and Barbenel J.C. Mechanical and failure behavior of the stratum-corneum. J. Biomech. 23 3 (1990) 281-287
30. Brujan E.A., Nahen K., Schmidt P., and Vogel A. Dynamics of laser-induced cavitation bubbles near elastic boundaries: influence of the elastic modulus. J. Fluid Mech. 433 (2001) 283-314
31. Ferruzzi G.G., Pan N., and Casey W.H. Mechanical properties of gellan and polyacrylamide gels with implications for soil stabilization. Soil Sci. 165 10 (2000) 778-792