Crystal structures of phosphite dehydrogenase provide insights into nicotinamide cofactor regeneration

Biochemistry

Volumn 51, Issue 21, 2012, Pages 4263-4270

  Zou, Yaozhong ^a   Zhang, Houjin ^a   Brunzelle, Joseph S ^c   Johannes, Tyler W ^b   Woodyer, Ryan ^b   Hung, John E ^b   Nair, Nikhil ^b   Van Der Donk, Wilfred A ^a,b   Zhao, Huimin ^a,b   Nair, Satish K ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c ARGONNE NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; BIOLOGICAL CATALYSTS; COCRYSTAL STRUCTURE; COFACTOR REGENERATION; ENZYMATIC ACTIVITIES; ENZYMATIC OXIDATIONS; MOLECULAR FRAMEWORKS; MUTATIONAL ANALYSIS; NICOTINAMIDE COFACTOR; PHOSPHITE DEHYDROGENASE; STRUCTURAL DATA;

AMIDES; PHOSPHORUS;

CATALYST ACTIVITY;

NICOTINAMIDE; NICOTINAMIDE COFACTOR; OXIDOREDUCTASE; PHOSPHITE DEHYDROGENASE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME DEGRADATION; ENZYME SPECIFICITY; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; THERMOSTABILITY;

AMINO ACID SUBSTITUTION; BACTERIAL PROTEINS; BINDING, COMPETITIVE; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; ENZYME STABILITY; LIGANDS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; NAD; NADH, NADPH OXIDOREDUCTASES; PROTEIN CONFORMATION; PROTEIN ENGINEERING; PSEUDOMONAS STUTZERI; RECOMBINANT PROTEINS; SULFITES;

EID: 84861615164     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi2016926     Document Type: Article

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