Osteostatin improves the osteogenic activity of fibroblast growth factor-2 immobilized in Si-doped hydroxyapatite in osteoblastic cells

Acta Biomaterialia

Volumn 8, Issue 7, 2012, Pages 2770-2777

  Lozano, Daniel ^a   Feito, María José ^b   Portal Núñez, Sergio ^a   Lozano, Rosa María ^c   Matesanz, María Concepción ^b   Serrano, María Concepción ^d   Vallet Regí, María ^e,f   Portolés, María Teresa ^b   Esbrit, Pedro ^a  

^a 28400 Madrid   (Spain)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^c CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^d INSTITUTO DE CIENCIA DE MATERIALES DE MADRID   (Spain)

^e Departamento de Química Inorgánica y Bioinorgánica   (Spain)

^f BIOMATERIALES Y NANOMEDICINA CIBER BBN   (Spain)

Author keywords

Fibroblast growth factor 2; Osteoblastic function; Osteostatin; Parathyroid hormone related protein; Si based hydroxyapatite

Indexed keywords

BIOMATERIALS; BONE; CELL CULTURE; CELL ENGINEERING; ENDOTHELIAL CELLS; ENZYME ACTIVITY; ENZYME INHIBITION; FIBROBLASTS; GENE EXPRESSION; PHOSPHATASES; TISSUE ENGINEERING;

DOPED HYDROXYAPATITES; FIBROBLAST GROWTH FACTOR-2; IN-VITRO; MC3T3-E1 CELL; OSTEOBLASTIC FUNCTIONS; OSTEOSTATIN; PARATHYROID HORMONE-RELATED PROTEIN; PARATHYROID HORMONES; SI-BASED; SI-BASED HYDROXYAPATITE;

HYDROXYAPATITE;

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; ALKALINE PHOSPHATASE; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR; HYDROXYAPATITE; IMMOBILIZED PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; OSTEOCALCIN; OSTEOSTATIN; PARATHYROID HORMONE RELATED PROTEIN; SILICON; SILICON BASED HYDROXYAPATITE FIBROBLAST GROWTH FACTOR 2 CONJUGATE; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR; VERAPAMIL;

ANGIOGENESIS; ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; BONE MINERALIZATION; CALCIUM CELL LEVEL; CELL GROWTH; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; DRUG POTENTIATION; ENDOTHELIUM CELL; ENZYME ACTIVITY; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IN VITRO STUDY; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN FUNCTION; SWINE; TISSUE ENGINEERING;

SUIDAE;

EID: 84861594444     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2012.04.002     Document Type: Article

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