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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 12, 2012, Pages 4059-4063

7-Azabicyclo[2.2.1]heptane as a scaffold for the development of selective sigma-2 (σ2) receptor ligands

(3) Banister, Samuel D a,b Rendina, Louis M a Kassiou, Michael a,b

a UNIVERSITY OF SYDNEY (Australia)

b UNIVERSITY OF SYDNEY (Australia)

Author keywords

Azanorbornanes; CNS; Pyrrolidines; Sigma receptors; Structure activity relationships

Indexed keywords

7 AZABICYCLO [2 2 1] HEPTANE; AMANTADINE; AZANORBORNANE; BORNANE DERIVATIVE; PYRROLIDINE DERIVATIVE; SIGMA 2 OPIATE RECEPTOR; TRISHOMOCUBANE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING ASSAY; CONFORMATIONAL TRANSITION; DRUG SYNTHESIS; IN VITRO STUDY; STRUCTURE ACTIVITY RELATION;

ADAMANTANE; ANIMALS; ANTIPSYCHOTIC AGENTS; AZABICYCLO COMPOUNDS; BINDING, COMPETITIVE; BRAIN CHEMISTRY; HEPTANES; HUMANS; KINETICS; LIGANDS; MOLECULAR STRUCTURE; NITROGEN; PROTEIN BINDING; PYRROLIDINES; RADIOLIGAND ASSAY; RATS; RECEPTORS, SIGMA; STRUCTURE-ACTIVITY RELATIONSHIP; TISSUE EXTRACTS;

EID: 84861576092 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2012.04.077 Document Type: Article

Times cited : (13)

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