Poly(propylene fumarate) reinforced dicalcium phosphate dihydrate cement composites for bone tissue engineering

Journal of Biomedical Materials Research - Part A

Volumn 100 A, Issue 7, 2012, Pages 1792-1802

  Alge, Daniel L ^a   Bennett, Jeffrey ^b   Treasure, Trevor ^b   Voytik Harbin, Sherry ^a   Goebel, W Scott ^c   Chu, Tien Min Gabriel ^b  

^a PURDUE UNIVERSITY   (United States)

^b INDIANA UNIVERSITY SCHOOL OF DENTISTRY   (United States)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

bone tissue engineering; calcium phosphate; composite; polymer; rapid prototyping

Indexed keywords

BONE NODULES; BONE TISSUE ENGINEERING; CALCIUM PHOSPHATE CEMENT; CALVARIAL DEFECTS; CEMENT COMPOSITE; COMPRESSIVE TESTING; DICALCIUM PHOSPHATE DIHYDRATE; FLEXURAL MODULUS; MACROPOROUS; MAXIMUM DISPLACEMENT; MESENCHYMAL STEM CELL; OSTEOCONDUCTIVITY; POLYPROPYLENE FUMARATE; POWDER TO LIQUID RATIO; RAPID PROTOTYPING TECHNOLOGY; RESORBABLE; SCAFFOLD FABRICATION; SCAFFOLD MATERIALS; WORK OF FRACTURE;

BONE; BONE CEMENT; CALCIUM PHOSPHATE; CELL CULTURE; CEMENTS; COMPOSITE MATERIALS; FRACTURE; MECHANICAL PROPERTIES; POLYMERS; PROPYLENE; RAPID PROTOTYPING; REINFORCEMENT; THREE DIMENSIONAL;

SCAFFOLDS (BIOLOGY);

BONE CEMENT; CALCIUM PHOSPHATE DIBASIC; NANOCOMPOSITE; POLY(PROPYLENE FUMARATE); TISSUE SCAFFOLD; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE REGENERATION; BONE TISSUE; BONE TISSUE ENGINEERING; COMPRESSIVE STRENGTH; CONTROLLED STUDY; EXPERIMENTAL RABBIT; FRACTURE; LIQUID; MALE; MESENCHYMAL STEM CELL; NANOFABRICATION; NONHUMAN; OSTEOBLAST; POWDER; SKULL DEFECT; TISSUE ENGINEERING; YOUNG MODULUS;

ANIMALS; BIOCOMPATIBLE MATERIALS; BONE AND BONES; BONE CEMENTS; CALCIUM PHOSPHATES; FUMARATES; MALE; POLYPROPYLENES; RABBITS; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84861574444     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.34130     Document Type: Article

References (50)

1. Chatterjea A, Meijer G, van Blitterswijk C, de Boer J,. Clinical application of human mesenchymal stromal cells for bone tissue engineering. Stem Cells Int 2010; 2010: 215625.
2. Mesimäki K, Lindroos B, Törnwall J, Mauno J, Lindqvist C, Kontio R, Miettinen S, Suuronen R,. Novel maxillary reconstruction with ectopic bone formation by GMP adipose stem cells. Int J Oral Maxillofac Surg 2009; 38: 201-209.
3. Quarto R, Mastrogiacomo M, Cancedda R, Kutepov SM, Mukhachev V, Lavroukov A, Kon E, Marcacci M,. Repair of large bone defects with the use of autologous bone marrow stromal cells. N Engl J Med 2001; 344: 385-386.
4. Marcacci M, Kon E, Moukhachev V, Lavroukov A, Kutepov S, Quarto R, Mastrogiacomo M, Cancedda R,. Stem cells associated with macroporous bioceramics for long bone repair: 6- to 7-year outcome of a pilot clinical study. Tissue Eng 2007; 13: 947-955.
5. Morishita T, Honoki K, Ohgushi H, Kotobuki N, Matsushima A, Takakura Y,. Tissue engineering approach to the treatment of bone tumors: Three cases of cultured bone grafts derived from patients' mesenchymal stem cells. Artif Organs 2006; 30: 115-118.
6. Arinzeh TL, Peter SJ, Archambault MP, van den Bos C, Gordon S, Kraus K, Smith A, Kadiyala S,. Allogeneic mesenchymal stem cells regenerate bone in a critical-sized canine segmental defect. J Bone Joint Surg Am 2003; 85-A: 1927-1935.
7. Arinzeh TL, Tran T, Mcalary J, Daculsi G,. A comparative study of biphasic calcium phosphate ceramics for human mesenchymal stem-cell-induced bone formation. Biomaterials 2005; 26: 3631-3638.
8. Wagoner Johnson AJ, Herschler BA,. A review of the mechanical behavior of CaP and CaP/polymer composites for applications in bone replacement and repair. Acta Biomater 2011; 7: 16-30.
9. Liu G, Zhao L, Zhang W, Cui L, Liu W, Cao Y,. Repair of goat tibial defects with bone marrow stromal cells and beta-tricalcium phosphate. J Mater Sci Mater Med 2008; 19: 2367-2376.
10. Barrère F, van Blitterswijk CA, de Groot K,. Bone regeneration: Molecular and cellular interactions with calcium phosphate ceramics. Int J Nanomedicine 2006; 1: 317-332.
11. LeGeros RZ,. Properties of osteoconductive biomaterials: Calcium phosphates. Clin Orthop Relat Res 2002; February: 81-98.
12. Ginebra MP, Espanol M, Montufar EB, Perez RA, Mestres G,. New processing approaches in calcium phosphate cements and their applications in regenerative medicine. Acta Biomater 2010; 6: 2863-2873.
13. Bohner M,. Calcium orthophosphates in medicine: From ceramics to calcium phosphate cements. Injury 2000; 31 Suppl 4: 37-47.
14. Theiss F, Apelt D, Brand B, Kutter A, Zlinszky K, Bohner M, Matter S, Frei C, Auer JA, von Rechenberg B,. Biocompatibility and resorption of a brushite calcium phosphate cement. Biomaterials 2005; 26: 4383-4394.
15. Apelt D, Theiss F, El-Warrak AO, Zlinszky K, Bettschart-Wolfisberger R, Bohner M, Matter S, Auer JA, von Rechenberg B,. In vivo behavior of three different injectable hydraulic calcium phosphate cements. Biomaterials 2004; 25: 1439-1451.
16. Khairoun I, Boltong MG, Driessens FC, Planell JA,. Some factors controlling the injectability of calcium phosphate bone cements. J Mater Sci Mater Med 1998; 9: 425-428.
17. Low KL, Tan SH, Zein SHS, Roether JA, Mouriño V, Boccaccini AR,. Calcium phosphate-based composites as injectable bone substitute materials. J Biomed Mater Res Part B Appl Biomater 2010; 94: 273-286.
18. Chu TM, Halloran JW, Hollister SJ, Feinberg SE,. Hydroxyapatite implants with designed internal architecture. J Mater Sci Mater Med 2001; 12: 471-478.
19. Hollister SJ, Lin CY, Saito E, Lin CY, Schek RD, Taboas JM, Williams JM, Partee B, Flanagan CL, Diggs A, Wilke EN, Van Lenthe GH, Müller R, Wirtz T, Das S, Feinberg SE, Krebsbach PH,. Engineering craniofacial scaffolds. Orthod Craniofac Res 2005; 8: 162-173.
20. Mitsak AG, Kemppainen JM, Harris MT, Hollister SJ,. Effect of Polycaprolactone Scaffold Permeability on Bone Regeneration In Vivo. Tissue Eng Part A 2011; 17: 1831-1839.
21. Ambard AJ, Mueninghoff L,. Calcium phosphate cement: Review of mechanical and biological properties. J Prosthodont 2006; 15: 321-328.
22. Gorst NJS, Perrie Y, Gbureck U, Hutton AL, Hofmann MP, Grover LM, Barralet JE,. Effects of fibre reinforcement on the mechanical properties of brushite cement. Acta Biomater 2006; 2: 95-102.
23. Zhang Y, Xu HHK,. Effects of synergistic reinforcement and absorbable fiber strength on hydroxyapatite bone cement. J Biomed Mater Res A 2005; 75: 832-840.
24. Xu HH, Eichmiller FC, Barndt PR,. Effects of fiber length and volume fraction on the reinforcement of calcium phosphate cement. J Mater Sci Mater Med 2001; 12: 57-65.
25. Alge DL, Chu T-MG,. Calcium phosphate cement reinforcement by polymer infiltration and in situ curing: A method for 3D scaffold reinforcement. J Biomed Mater Res A 2010; 94: 547-555.
26. Chang C-H, Liao T-C, Hsu Y-M, Fang H-W, Chen C-C, Lin F-H,. A poly(propylene fumarate)-calcium phosphate based angiogenic injectable bone cement for femoral head osteonecrosis. Biomaterials 2010; 31: 4048-4055.
27. Peter SJ, Miller ST, Zhu G, Yasko AW, Mikos AG,. In vivo degradation of a poly(propylene fumarate)/beta-tricalcium phosphate injectable composite scaffold. J Biomed Mater Res 1998; 41: 1-7.
28. Kim K, Dean D, Mikos AG, Fisher JP,. Effect of initial cell seeding density on early osteogenic signal expression of rat bone marrow stromal cells cultured on cross-linked poly(propylene fumarate) disks. Biomacromolecules 2009; 10: 1810-1817.
29. Lee K-W, Wang S, Yaszemski MJ, Lu L,. Physical properties and cellular responses to crosslinkable poly(propylene fumarate)/hydroxyapatite nanocomposites. Biomaterials 2008; 29: 2839-2848.
30. Alge DL, Goebel WS, Chu T-MG,. In vitro degradation and cytocompatibility of dicalcium phosphate dihydrate cements prepared using the monocalcium phosphate monohydrate/hydroxyapatite system reveals rapid conversion to HA as a key mechanism. J Biomed Mater Res Part B Appl Biomater. 2012; 100: 595-602.
31. Li Y, Chen S, Yuan J, Yang Y, Li J, Ma J, Wu X, Freund M, Pollok K, Hanenberg H, Goebel WS, Yang FC,. Mesenchymal stem/progenitor cells promote the reconstitution of exogenous hematopoietic stem cells in Fancg-/- mice in vivo. Blood 2009; 113: 2342-51.
32. Vermes I, Haanen C, Steffens-Nakken H, Reutelingsperger C,. A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V. J Immunol Methods 1995; 184: 39-51.
33. Kreger ST, Bell BJ, Bailey J, Stites E, Kuske J, Waisner B, Voytik-Harbin SL,. Polymerization and matrix physical properties as important design considerations for soluble collagen formulations. Biopolymers 2010; 93: 690-707.
34. Alge DL, Zhou D, Adams LL, Wyss BK, Shadday MD, Woods EJ, Chu T-MG, Goebel WS,. Donor-matched comparison of dental pulp stem cells and bone marrow-derived mesenchymal stem cells in a rat model. J Tissue Eng Regen Med 2010; 4: 73-81.
35. Chu TMG, Orton DG, Hollister SJ, Feinberg SE, Halloran JW,. Mechanical and in vivo performance of hydroxyapatite implants with controlled architectures. Biomaterials 2002; 23: 1283-1293.
36. Alge DL, Santa Cruz G, Goebel WS, Chu T-MG,. Characterization of dicalcium phosphate dihydrate cements prepared using a novel hydroxyapatite-based formulation. Biomed Mater 2009; 4: 025016.
37. Bohner M, Baroud G,. Injectability of calcium phosphate pastes. Biomaterials 2005; 26: 1553-1563.
38. Chen W-C, Ju C-P, Wang J-C, Hung C-C, Chern Lin J-H,. Brittle and ductile adjustable cement derived from calcium phosphate cement/polyacrylic acid composites. Dent Mater 2008; 24: 1616-1622.
39. Xu HHK, Quinn JB, Takagi S, Chow LC,. Processing and properties of strong and non-rigid calcium phosphate cement. J Dent Res 2002; 81: 219-224.
40. Fernández E, Gil FJ, Ginebra MP, Driessens FC, Planell JA, Best SM,. Calcium phosphate bone cements for clinical applications. Part I: Solution chemistry. J Mater Sci Mater Med 1999; 10: 169-176.
41. Charrière E, Terrazzoni S, Pittet C, Mordasini PH, Dutoit M, Lemaître J, Zysset PH,. Mechanical characterization of brushite and hydroxyapatite cements. Biomaterials 2001; 22: 2937-2945.
42. Timmer MD, Jo S, Wang C, Ambrose CG, Mikos AG,. Characterization of the cross-linked structure of fumarate-based degradable polymer networks. Macromolecules 2002; 35: 4373-4379.
43. Yaszemski MJ, Payne RG, Hayes WC, Langer R, Mikos AG,. In vitro degradation of a poly(propylene fumarate)-based composite material. Biomaterials 1996; 17: 2127-2130.
44. Wu C-C, Yang K-C, Yang S-H, Lin M-H, Kuo T-F, Lin F-H,. In vitro studies of composite bone filler based on poly(propylene fumarate) and biphasic α-tricalcium phosphate/hydroxyapatite ceramic powder. Artif Organs. DOI: 10.1111/j.1525-1594.2011.01372.x.
45. Chu T-MG, Warden SJ, Turner CH, Stewart RL,. Segmental bone regeneration using a load-bearing biodegradable carrier of bone morphogenetic protein-2. Biomaterials 2007; 28: 459-467.
46. Lewandrowski K-U, Bondre SP, Wise DL, Trantolo DJ,. Enhanced bioactivity of a poly(propylene fumarate) bone graft substitute by augmentation with nano-hydroxyapatite. Biomed Mater Eng 2003; 13: 115-124.
47. Cai Z, Zhang T, Di L, Xu D-M, Xu D-H, Yang D-A,. Morphological and histological analysis on the in vivo degradation of poly (propylene fumarate)/(calcium sulfate/β-tricalcium phosphate). Biomed Microdevices 2011; 13: 623-31.
48. Gbureck U, Hölzel T, Klammert U, Würzler K, Müller FA, Barralet JE,. Resorbable dicalcium phosphate bone substitutes prepared by 3D powder printing. Adv Funct Mater 2007; 17: 3940-3945.
49. Schantz J-T, Hutmacher DW, Lam CXF, Brinkmann M, Wong KM, Lim TC, Chou N, Guldberg RE, Teoh SH,. Repair of calvarial defects with customised tissue-engineered bone grafts II. Evaluation of cellular efficiency and efficacy in vivo. Tissue Eng 2003; 9 Suppl 1: S127-S139.
50. Dean D, Wolfe MS, Ahmad Y, Totonchi A, Chen JE-K, Fisher JP, Cooke MN, Rimnac CM, Lennon DP, Caplan AI, Topham NS, Mikos AG,. Effect of transforming growth factor beta 2 on marrow-infused foam poly(propylene fumarate) tissue-engineered constructs for the repair of critical-size cranial defects in rabbits. Tissue Eng 2005; 11: 923-939.