Methylenetetrahydrofolate reductase C677T gene polymorphism and coronary artery disease in a Chinese Han population: A meta-analysis

Metabolism: Clinical and Experimental

Volumn 61, Issue 6, 2012, Pages 846-852

  Li, Yan Yan ^a  

^a THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2);

ARTICLE; CARDIOVASCULAR RISK; CHINESE; CORONARY ARTERY DISEASE; DNA POLYMORPHISM; GENETIC ASSOCIATION; GENOTYPE; HUMAN; PRIORITY JOURNAL;

ASIAN CONTINENTAL ANCESTRY GROUP; CORONARY ARTERY DISEASE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84861573241     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2011.10.013     Document Type: Article

References (38)

1. M.J. Stampfer, M.R. Malinow, and W.C. Willett A prospective study of plasma homocyst(e)ine and risk of myocardial infarction in US physicians JAMA 268 1992 877 881
2. P. Goyette, A. Pai, and R. Milos Gene structure of human and mouse methylenetetrahydrofolate reductase (MTHFR) Mamm Genome 9 1998 652 656
3. P. Frosst, H.J. Blom, and R. Milos A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase Nat Genet 10 1995 111 113
4. A. Imamura, R. Murakami, and R. Takahashi Low folate levels may be an atherogenic factor regardless of homocysteine levels in young healthy nonsmokers Metabolism 59 2010 728 733
5. R. Dankner, A. Chetrit, and H. Murad Serum adiponectin is associated with homocysteine in elderly men and women, and with 5,10-methylenetetrahydrofolate reductase (MTHFR) in a sex-dependent manner Metabolism 59 2010 1767 1774
6. C.H. Ho Prevalence of prothrombin 20210A allele and methylenetetrahydrofolate reductase C677T genetic mutations in the Chinese population Ann Hematol 79 2000 239 242
7. I.J. Kullo, and C.M. Ballantyne Conditional risk factors for atherosclerosis Mayo Clin Proc 80 2005 219 230
8. T.F. Ashavaid, K.K. Shalia, A.A. Kondkar, S.P. Todur, K.G. Nair, and S.R. Nair Gene polymorphism and coronary risk factors in Indian population Clin Chem Lab Med 40 2002 975 985
9. C.W. Dai, and G.S. Zhang Study on homocysteine metabolism related enzymes gene mutation in Chinese patients with ischemic cardiovascular and cerebrovascular disease Chin J Hematol 22 2001 484 487
10. Y.M. Mao, F.M. Zhao, and Q. Qin Association of methylenetetrahydrofolate reductase gene polymorphism, level of homocysteine and coronary heart disease Tianjin Med J 30 2002 451 453
11. X. Xu, S.Q. Chen, and F.Y. Xie The study of the relationship between polymorphisms of methylenetetrahydrofolate gene and coronary heart disease Chin J Prim Med and Pharm 12 2005 661 662
12. X.B. Li, Y. Li, and Y.P. Li The relationship between coronary heart disease and methylenetetrahydrofolate reductase in elderly China Pract Med 5 2010 24 25
13. Y.N. Gu, and S.B. Jia Study on the polymorphism of MTHFR gene in Hui patient with coronary heart disease in Ningxia J Clin Cardiol 25 2009 439 441
14. H.Y. Xu, Z.J. Chen, and J. Tang C677T genetic polymorphism of methylenetetrahydrofolate reductase in premature coronary heart disease Acta Academiae Medicinae Sinicae 21 1999 118 121
15. L.G. Fang, W.L. Zhu, and G.J. Zhu Methylenetetrahydrofolate reductase gene polymorphism, homocysteine, folate and coronary artery disease Chin J Cardiol 30 2002 515 519
16. W.G. Cochran The effectiveness of adjustment by subclassification in removing bias in observational studies Biometrics 24 1968 295 313
17. R. DerSimonian, and N. Laird Meta-analysis in clinical trials Control Clin Trials 7 1986 177 188
18. N. Mantel, and W. Haenszel Statistical aspects of the analysis of data from retrospective studies of disease J Natl Cancer Inst 22 1959 719 748
19. M. Egger, and G. Davey Smith Bias in meta-analysis detected by a simple, graphical test BMJ 315 1997 629 634
20. Q.Q. Gao, L.X. Xu, and H.Q. Zhang Relationship between folate and methylenetetrahydrofolate reductase gene C677T polymorphisms and acute myocardial infarction Journal of Wenzhou Medical College 34 2004 423 425
21. B.Q. Jiang, G.M. Zhu, and Q.Q. Bao Study on the relationship between polymorphisms of methylenetetrahydrofolate reductase gene and coronary heart disease Journal of Wenzhou Medical College (Health Sciences) 42 2004 619 620
22. L.Y. Li, D.Q. Jiang, and Z.Y. Liu Concentration of plasma homocysteine and the gene types of methylenetetrahydrofolate reductase C677T in patients with coronary heart disease and their clinical significance Chin J Arterioscler 13 2005 210 214
23. H. Mu, and X. Chen Methylenetetrahydrofolate reductase gene mutation with AMI and stroke Sect Clin Biochem Lab Med Foreign Med Sci 26 2005 145 147
24. J. Niu, Z. Zhang, and M.Z. Chen Clinical study on effect of common methylenetetrahydrofolate reductase gene mutation on coronary artery disease in hypertension Chin J Interv Cardiol 13 2005 25 27
25. Y.L. Chen, X.Y. Zhang, and X.J. Xu Correlation of the polymorphism of methylenetetrahydrofolate reductase gene and plasma homocysteine with coronary heart disease in Uygur and Han ethnic groups in Xinjiang J Clin Rehabilitative Tissue Eng Res 11 2007 3206 3209
26. D. Luo, S.K. Yan, and L.Z. Wei The relationship between homocysteine metabolism related enzymes gene polymorphism and type 2 diabetes mellitus with coronary heart disease Chin J Gerontol 2007 541 543
27. L.Y. Yang, Y. He, and D.Z. Yang Detection of homocysteine metabolism related enzymes polymorphisms in Han population with coronary heart disease in Henan province Journal of Zhengzhou University (Medical Sciences) 46 2011 67 70
28. N.Q. Hanson, O. Aras, and F. Yang C677T and A1298C polymorphisms of the methylenetetrahydrofolate reductase gene: incidence and effect of combined genotypes on plasma fasting and post-methionine load homocysteine in vascular disease Clin Chem 47 2001 661 666
29. M.G. Andreassi, N. Botto, and F. Cocci Methylenetetrahydrofolate reductase gene C677T polymorphism, homocysteine, vitamin B12, and DNA damage in coronary artery disease Hum Genet 112 2003 171 177
30. R.P. Kloppenborg, P.J. Nederkoorn, and Y. van der Graaf Homocysteine and cerebral small vessel disease in patients with symptomatic atherosclerotic disease. The SMART-MR study Atherosclerosis 216 2011 461 466
31. P. Codoñer-Franch, S. Tavárez-Alonso, and R. Murria-Estal Nitric oxide production is increased in severely obese children and related to markers of oxidative stress and inflammation Atherosclerosis 215 2011 475 480
32. L. Yan-Yan Relationship of serum homocysteine and high sensitivity C-reactive protein in elderly people with essential hypertension Int J Clin Pract 64 2010 1318 1319
33. P.M. Biselli, A.R. Guerzoni, and E.M. Goloni-Bertollo MTHFR genetic variability on coronary artery disease development Rev Assoc Med Bras 55 2009 274 278
34. A.R. Guerzoni, P.M. Biselli, and M.F. Godoy Homocysteine and MTHFR and VEGF gene polymorphisms: impact on coronary artery disease Arq Bras Cardiol 92 2009 263 268
35. Z. Rahimi, H. Nomani, and H. Mozafari Factor V G1691A, prothrombin G20210A and methylenetetrahydrofolate reductase polymorphism C677T are not associated with coronary artery disease and type 2 diabetes mellitus in western Iran Blood Coagul Fibrinolysis 20 2009 252 256
36. A. Mager, N. Koren-Morag, and M. Shohat Impact of ethnicity and MTHFR genotype on age at onset of coronary artery disease in women in Israel Isr Med Assoc J 10 2008 516 519
37. S.V. Vijaya Lakshmi, and S.M. Naushad Interactions of 5'-UTR thymidylate synthase polymorphism with 677C→T methylene tetrahydrofolate reductase and 66A→G methyltetrahydrofolate homocysteine methyl-transferase reductase polymorphisms determine susceptibility to coronary artery disease J Atheroscler Thromb 18 2011 56 64
38. R. Belkahla, A. Omezzine, and K. Kchok Effect of polymorphisms on key enzymes in homocysteine metabolism, on plasma homocysteine level and on coronary artery-disease risk in a Tunisian population Ann Cardiol Angeiol (Paris) 57 2008 219 224