메뉴 건너뛰기




Volumn 55, Issue 3, 2009, Pages 274-278

MTHFR genetic variability on coronary artery disease development;Variabilidade genética MTHFR no desenvolvimento da doença arterial Coronária

Author keywords

Coronary artery disease; Genetic polymorphisms; MTHFR enzyme

Indexed keywords


EID: 69249137531     PISSN: 01044230     EISSN: None     Source Type: Journal    
DOI: 10.1590/s0104-42302009000300018     Document Type: Article
Times cited : (11)

References (28)
  • 2
    • 0031748093 scopus 로고    scopus 로고
    • The metabolism of homocysteine: Pathways and regulation
    • Finkelstein JD. The metabolism of homocysteine: pathways and regulation. Eur J Pediatr. 1998;157(Suppl 2):40-4.
    • (1998) Eur J Pediatr , vol.157 , Issue.SUPPL. 2 , pp. 40-44
    • Finkelstein, J.D.1
  • 3
    • 0036377016 scopus 로고    scopus 로고
    • The common mutations C677T and A1298C in the human methylenetetrahydrofolate reductase gene are associated with hyperhomocysteinemia and cardiovascular disease in hemodialysis patients
    • Haviv YS, Shpichinetsky V, Goldschmidt N, Atta IA, Ben-Yehuda A, Friedman G. The common mutations C677T and A1298C in the human methylenetetrahydrofolate reductase gene are associated with hyperhomocysteinemia and cardiovascular disease in hemodialysis patients. Nephron. 2002;92:120-6.
    • (2002) Nephron , vol.92 , pp. 120-126
    • Haviv, Y.S.1    Shpichinetsky, V.2    Goldschmidt, N.3    Atta, I.A.4    Ben-Yehuda, A.5    Friedman, G.6
  • 4
    • 0034743914 scopus 로고    scopus 로고
    • The 1298A3C polymorphism in methylenetetrahydrofolate reductase (MTHFR): In vitro expression and association with homocysteine
    • Weisberg IS, Jacques PF, Selhub J, Bostom AG, Chen Z, Ellison RC, et al. The 1298A3C polymorphism in methylenetetrahydrofolate reductase (MTHFR): in vitro expression and association with homocysteine. Atherosclerosis. 2001;156:409-15.
    • (2001) Atherosclerosis , vol.156 , pp. 409-415
    • Weisberg, I.S.1    Jacques, P.F.2    Selhub, J.3    Bostom, A.G.4    Chen, Z.5    Ellison, R.C.6
  • 5
    • 0031687887 scopus 로고    scopus 로고
    • A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity
    • Weisberg I, Tran P, Christensen B, Sibani S, Rozen R. A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity. Mol Genet Metab. 1998;64:169-72.
    • (1998) Mol Genet Metab , vol.64 , pp. 169-172
    • Weisberg, I.1    Tran, P.2    Christensen, B.3    Sibani, S.4    Rozen, R.5
  • 6
    • 0035909980 scopus 로고    scopus 로고
    • Effects of common polymorphisms on the properties of recombinant human methylenetetrahydrofolate reductase
    • Yamada K, Chen Z, Rozen R, Matthews RG. Effects of common polymorphisms on the properties of recombinant human methylenetetrahydrofolate reductase. Proc Natl Acad Sci USA. 2001;98:14853-8.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 14853-14858
    • Yamada, K.1    Chen, Z.2    Rozen, R.3    Matthews, R.G.4
  • 7
    • 0032763113 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase genotypes and early-onset coronary artery disease
    • Mager A, Lalezari S, Shohat T, Birnbaum Y, Adler Y, Magal N, et al. Methylenetetrahydrofolate reductase genotypes and early-onset coronary artery disease. Circulation. 1999;100:2406-10.
    • (1999) Circulation , vol.100 , pp. 2406-2410
    • Mager, A.1    Lalezari, S.2    Shohat, T.3    Birnbaum, Y.4    Adler, Y.5    Magal, N.6
  • 8
    • 0035880967 scopus 로고    scopus 로고
    • MTHFR677C T mutation: A predictor of early-onset coronary artery disease
    • Payne DA, Chamoun AJ, Seifert SI, Stouffer GA. MTHFR677C T mutation: a predictor of early-onset coronary artery disease. Thromb Res. 2001;103:275-9.
    • (2001) Thromb Res , vol.103 , pp. 275-279
    • Payne, D.A.1    Chamoun, A.J.2    Seifert, S.I.3    Stouffer, G.A.4
  • 9
    • 0035370968 scopus 로고    scopus 로고
    • Mutation A1298C of methylenetetrahydrofolate reductase: Risk for early coronary disease not associated with hyperhomocysteinemia
    • Szczeklik A, Sanak M, Jankowski M, Dropinski J, Czachor R, Musial J, et al. Mutation A1298C of methylenetetrahydrofolate reductase: risk for early coronary disease not associated with hyperhomocysteinemia. Am J Med Genet. 2001;101:36-9.
    • (2001) Am J Med Genet , vol.101 , pp. 36-39
    • Szczeklik, A.1    Sanak, M.2    Jankowski, M.3    Dropinski, J.4    Czachor, R.5    Musial, J.6
  • 10
    • 17044387295 scopus 로고    scopus 로고
    • An association between the methylenetetrahydrofolate reductase (MTHFR) C677T mutation and inflammation markers related to cardiovascular disease
    • Dedoussis GVZ, Panagiotakos DB, Pitsavos C, Chrysohoou C, Skoumas J, Choumerianou D, et al. An association between the methylenetetrahydrofolate reductase (MTHFR) C677T mutation and inflammation markers related to cardiovascular disease. Int J Cardiol. 2005;100:409-14.
    • (2005) Int J Cardiol , vol.100 , pp. 409-414
    • Dedoussis, G.V.Z.1    Panagiotakos, D.B.2    Pitsavos, C.3    Chrysohoou, C.4    Skoumas, J.5    Choumerianou, D.6
  • 11
    • 0030825259 scopus 로고    scopus 로고
    • Gene Polymorphism of 5, 10-methylenetetrahydrofolate reductase as a coronary risk factor
    • Morita H, Taguchi J, Kurihara H, Kitaoka M, Kaneda H, Kurihara Y, et al. Gene Polymorphism of 5, 10-methylenetetrahydrofolate reductase as a coronary risk factor. J Cardiol. 1997;29:309-15.
    • (1997) J Cardiol , vol.29 , pp. 309-315
    • Morita, H.1    Taguchi, J.2    Kurihara, H.3    Kitaoka, M.4    Kaneda, H.5    Kurihara, Y.6
  • 12
    • 20244366362 scopus 로고    scopus 로고
    • Genetic causes of mild hyperhomocysteinemia in patients with premature occlusive coronary artery diseases
    • Tsai MY, Welge BG, Hanson NQ, Bignell MK, Vessey J, Schwichtenberg K, et al. Genetic causes of mild hyperhomocysteinemia in patients with premature occlusive coronary artery diseases. Atherosclerosis. 1999;143:163-70.
    • (1999) Atherosclerosis , vol.143 , pp. 163-170
    • Tsai, M.Y.1    Welge, B.G.2    Hanson, N.Q.3    Bignell, M.K.4    Vessey, J.5    Schwichtenberg, K.6
  • 13
    • 0032866058 scopus 로고    scopus 로고
    • The A677V methylenetetrahydrofolate reductase gene polymorphism and carotid atherosclerosis
    • Bova I, Chapman J, Sylantiev C, Korczyn AD, Bornstein NM. The A677V methylenetetrahydrofolate reductase gene polymorphism and carotid atherosclerosis. Stroke. 1999;30:2180-2.
    • (1999) Stroke , vol.30 , pp. 2180-2182
    • Bova, I.1    Chapman, J.2    Sylantiev, C.3    Korczyn, A.D.4    Bornstein, N.M.5
  • 14
    • 0036705558 scopus 로고    scopus 로고
    • Major gene evidence after MTHFR-segregation analysis of serum homocysteine in families of patients undergoing coronary arteriography
    • Jee SH, Song KS, Shim WH, Kim HK, Suh I, Park JY, et al. Major gene evidence after MTHFR-segregation analysis of serum homocysteine in families of patients undergoing coronary arteriography. Hum Genet. 2002;111:128-35.
    • (2002) Hum Genet , vol.111 , pp. 128-135
    • Jee, S.H.1    Song, K.S.2    Shim, W.H.3    Kim, H.K.4    Suh, I.5    Ark, J.Y.6
  • 15
    • 2342485635 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase gene C677T and A1298C polymorphisms, plasma homocysteine, folate, and vitamin B12 levels and the extent of coronary artery disease
    • Kolling K, Ndrepepa G, Koch W, Braun S, Mehilli J, Schomig A, et al. Methylenetetrahydrofolate reductase gene C677T and A1298C polymorphisms, plasma homocysteine, folate, and vitamin B12 levels and the extent of coronary artery disease. Am J Cardiol. 2004;93:1201-6.
    • (2004) Am J Cardiol , vol.93 , pp. 1201-1206
    • Kolling, K.1    Ndrepepa, G.2    Koch, W.3    Braun, S.4    Mehilli, J.5    Schomig, A.6
  • 16
    • 24944545722 scopus 로고    scopus 로고
    • Association of MTRRA66G polymorphism (but not of MTHFR C677T and A1298C, MTRA2756G, TCN C776G) with homocysteine and coronary disease in the French population
    • Gueant-Rodriguez RM, Juilliere Y, Candito M, Adjalla CE, Gibelin P, Herbeth B, et al. Association of MTRRA66G polymorphism (but not of MTHFR C677T and A1298C, MTRA2756G, TCN C776G) with homocysteine and coronary disease in the French population. Thromb Haemost. 2005;94:510-5.
    • (2005) Thromb Haemost , vol.94 , pp. 510-515
    • Gueant-Rodriguez, R.M.1    Juilliere, Y.2    Candito, M.3    Adjalla, C.E.4    Gibelin, P.5    Herbeth, B.6
  • 17
    • 33846378138 scopus 로고    scopus 로고
    • Avaliação da relação entre o polimorfismo C677T no gene para MTHFR e a concentração plamática de homocisteína na doença arterial coronariana
    • Muniz MTC, Siqueira ERF, Fonseca RA, D'Almeida V, Hotta JK, Santos JE, et al. Avaliação da relação entre o polimorfismo C677T no gene para MTHFR e a concentração plamática de homocisteína na doença arterial coronariana. Arq Bras Endocrinol Metab. 2006;50:1059-65.
    • (2006) Arq Bras Endocrinol Metab , vol.50 , pp. 1059-1065
    • Muniz, M.T.C.1    Siqueira, E.R.F.2    Fonseca, R.A.3    D'Almeida, V.4    Hotta, J.K.5    Santos, J.E.6
  • 18
    • 0031902128 scopus 로고    scopus 로고
    • Prevalence of the mutation C677-->T in the methylenetetrahydrofolate reductase gene among distinct ethnic groups in Brazil
    • Arruda VR, Siqueira LH, Goncalves MS, Von Zuben PM, Soares MC, Menezes R, et al. Prevalence of the mutation C677-->T in the methylenetetrahydrofolate reductase gene among distinct ethnic groups in Brazil. Am J Med. 1998;78:332-5.
    • (1998) Am J Med , vol.78 , pp. 332-335
    • Arruda, V.R.1    Siqueira, L.H.2    Goncalves, M.S.3    von Zuben, P.M.4    Soares, M.C.5    Menezes, R.6
  • 19
    • 0028492502 scopus 로고
    • Molecular interaction of 2,3-[14C]-acrylonitrile with DNA in gastric tissues of rat
    • Abdel-Rahman SZ, Nouraldeen AM, Ahmed AE. Molecular interaction of 2,3-[14C]-acrylonitrile with DNA in gastric tissues of rat. J Biochem Toxicol. 1994;9:12128.
    • (1994) J Biochem Toxicol , vol.9 , pp. 12128
    • Abdel-Rahman, S.Z.1    Nouraldeen, A.M.2    Ahmed, A.E.3
  • 20
    • 0042974212 scopus 로고    scopus 로고
    • Risk factors and methylenetetrahydrofolate reductase gene polymorphisms in a young South African Indian-based population with acute myocardial infarction
    • Ranjith N, Pegoraro RJ, Rom L. Risk factors and methylenetetrahydrofolate reductase gene polymorphisms in a young South African Indian-based population with acute myocardial infarction. Cardiovasc J South Afr. 2003;14:127-32.
    • (2003) Cardiovasc J South Afr , vol.14 , pp. 127-132
    • Ranjith, N.1    Pegoraro, R.J.2    Rom, L.3
  • 21
    • 0032499024 scopus 로고    scopus 로고
    • Homocysteine and atherothrombosis
    • Welch GN, Loscalzo J. Homocysteine and atherothrombosis. N Engl J Med. 1998;338:1042-50.
    • (1998) N Engl J Med , vol.338 , pp. 1042-1050
    • Welch, G.N.1    Loscalzo, J.2
  • 22
    • 0036847780 scopus 로고    scopus 로고
    • Increased monocyte adhesion to aortic endothelium in rats with hyperhomocysteinemia: Role of chemokine and adhesion molecules
    • O K
    • Wang G, Woo CW, Sung FL, Siow YL, O K. Increased monocyte adhesion to aortic endothelium in rats with hyperhomocysteinemia: role of chemokine and adhesion molecules. Arterioscler Thromb Vasc Biol. 2002;22:1777-83.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 1777-1783
    • Wang, G.1    Woo, C.W.2    Sung, F.L.3    Siow, Y.L.4
  • 23
    • 0036120318 scopus 로고    scopus 로고
    • Homocysteine upregulates vascular cell adhesion molecule-1 expression in cultured human aortic endothelial cells and enhances monocyte adhesion
    • Silverman MD, Tumuluri RJ, Davis M, Lopez G, Rosenbaum JT, Lelkes PI. Homocysteine upregulates vascular cell adhesion molecule-1 expression in cultured human aortic endothelial cells and enhances monocyte adhesion. Arterioscler Thromb Vasc Biol. 2002;22:587-92.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 587-592
    • Silverman, M.D.1    Tumuluri, R.J.2    Davis, M.3    Lopez, G.4    Rosenbaum, J.T.5    Lelkes, P.I.6
  • 24
    • 33847346938 scopus 로고    scopus 로고
    • Relationship of the 1793G-A and 677C-T polymorphisms of the 5,10-methyle-netetrahydrofolate reductase gene to coronary artery disease
    • Kebert CB, Eichner JE, Moore WE, Schechter E, Yaoi T, Vogel S, et al. Relationship of the 1793G-A and 677C-T polymorphisms of the 5,10-methyle-netetrahydrofolate reductase gene to coronary artery disease. Dis Markers. 2006;22:293-301.
    • (2006) Dis Markers , vol.22 , pp. 293-301
    • Kebert, C.B.1    Eichner, J.E.2    Moore, W.E.3    Schechter, E.4    Yaoi, T.5    Vogel, S.6
  • 25
    • 33947170999 scopus 로고    scopus 로고
    • Thermolabile methylenetetrahydrofolate reductase C677T polymorphism and homocysteine are risk factors for coronary artery disease in moroccan population
    • Bennouar N, Allami A, Azeddoug H, Bendris A, Laraqui A, El Jaffali A, et al. Thermolabile methylenetetrahydrofolate reductase C677T polymorphism and homocysteine are risk factors for coronary artery disease in moroccan population. J Biomed Biotechnol. 2007;2007:806-87.
    • (2007) J Biomed Biotechnol , pp. 806-887
    • Bennouar, N.1    Allami, A.2    Azeddoug, H.3    Bendris, A.4    Laraqui, A.5    El Jaffali, A.6
  • 28
    • 0035864638 scopus 로고    scopus 로고
    • Identification of six methylenetetrahydrofolate reductase (MTHFR) genotypes resulting from common polymorphisms: Impact on plasma homocysteine levels and development of coronary artery disease
    • Meisel C, Cascorbi I, Gerloff T, Stangl V, Laule M, Müller JM. Identification of six methylenetetrahydrofolate reductase (MTHFR) genotypes resulting from common polymorphisms: impact on plasma homocysteine levels and development of coronary artery disease. Atherosclerosis. 2001;15.
    • (2001) Atherosclerosis , vol.15
    • Meisel, C.1    Cascorbi, I.2    Gerloff, T.3    Stangl, V.4    Laule, M.5    Müller, J.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.