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Volumn 7, Issue 5, 2012, Pages

Localization of the drosophila rad9 protein to the nuclear membrane is regulated by the C-terminal region and is affected in the meiotic checkpoint

Author keywords

[No Author keywords available]

Indexed keywords

BARRIER TO AUTOINTEGRATION FACTOR; PROTEIN RAD9; BAF PROTEIN, DROSOPHILA; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; DROSOPHILA PROTEIN; MESSENGER RNA; NUCLEAR PROTEIN;

EID: 84861553103     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0038010     Document Type: Article
Times cited : (8)

References (36)
  • 1
  • 2
    • 34250379523 scopus 로고    scopus 로고
    • The checkpoint clamp, Rad9-Rad1-Hus1 complex, preferentially stimulates the activity of apurinic/apyrimidinic endonuclease 1 and DNA polymerase β in long patch base excision repair
    • Gembka A, Toueille M, Smirnova E, Poltz R, Ferrari E, et al. (2007) The checkpoint clamp, Rad9-Rad1-Hus1 complex, preferentially stimulates the activity of apurinic/apyrimidinic endonuclease 1 and DNA polymerase β in long patch base excision repair. Nucleic Acids Res 35: 2596-2608.
    • (2007) Nucleic Acids Res , vol.35 , pp. 2596-2608
    • Gembka, A.1    Toueille, M.2    Smirnova, E.3    Poltz, R.4    Ferrari, E.5
  • 3
    • 35549003626 scopus 로고    scopus 로고
    • The human checkpoint sensor Rad9-Rad1-Hus1 interacts with and stimulates DNA repair enzyme TDG glycosylase
    • Guan X, Madabushi A, Chang DY, Fitzgerald ME, Shi G, et al. (2007) The human checkpoint sensor Rad9-Rad1-Hus1 interacts with and stimulates DNA repair enzyme TDG glycosylase. Nucleic Acids Res 35 (18): 6207-18.
    • (2007) Nucleic Acids Res , vol.35 , Issue.18 , pp. 6207-6218
    • Guan, X.1    Madabushi, A.2    Chang, D.Y.3    Fitzgerald, M.E.4    Shi, G.5
  • 5
    • 33845735505 scopus 로고    scopus 로고
    • DNA Damage Checkpoints Are Involved in Postreplication Repair
    • Barbour L, Ball LG, Zhang K, Xiao W, (2006) DNA Damage Checkpoints Are Involved in Postreplication Repair. Genetics 174: 1789-1800.
    • (2006) Genetics , vol.174 , pp. 1789-1800
    • Barbour, L.1    Ball, L.G.2    Zhang, K.3    Xiao, W.4
  • 6
    • 0042691728 scopus 로고    scopus 로고
    • The checkpoint protein Rad24 of Saccharomyces cerevisiae is involved in processing double-strand break ends and in recombination partner choice
    • Aylon Y, Kupiec M, (2003) The checkpoint protein Rad24 of Saccharomyces cerevisiae is involved in processing double-strand break ends and in recombination partner choice. Mol Cell Biol 23: 6585-6596.
    • (2003) Mol Cell Biol , vol.23 , pp. 6585-6596
    • Aylon, Y.1    Kupiec, M.2
  • 7
    • 0032822543 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae checkpoint genes MEC1, RAD17 and RAD24 are required for normal meiotic recombination partner choice
    • Grushcow JM, Holzen TM, Park KJ, Weinert T, Lichten M, et al. (1999) Saccharomyces cerevisiae checkpoint genes MEC1, RAD17 and RAD24 are required for normal meiotic recombination partner choice. Genetics 153: 607-620.
    • (1999) Genetics , vol.153 , pp. 607-620
    • Grushcow, J.M.1    Holzen, T.M.2    Park, K.J.3    Weinert, T.4    Lichten, M.5
  • 8
    • 33644555829 scopus 로고    scopus 로고
    • Mammalian rad9 plays a role in telomere stability, S- and G2-Phase-specific cell survival, and homologous recombinational repair
    • Pandita, RK, Sharma GG, Laszlo A, Hopkins KM, Davey S, et al. (2006) Mammalian rad9 plays a role in telomere stability, S- and G2-Phase-specific cell survival, and homologous recombinational repair. Mol Cell Biol 26: 1850-1864.
    • (2006) Mol Cell Biol , vol.26 , pp. 1850-1864
    • Pandita, R.K.1    Sharma, G.G.2    Laszlo, A.3    Hopkins, K.M.4    Davey, S.5
  • 9
    • 0033794570 scopus 로고    scopus 로고
    • Human homologue of S. pombe Rad9 interacts with BCL-2/BCL-xL and promotes apoptosis
    • Komatsu K, Miyashita T, Hang H, (2000) Human homologue of S. pombe Rad9 interacts with BCL-2/BCL-xL and promotes apoptosis. Nat Cell Biol 2: 1-6.
    • (2000) Nat Cell Biol , vol.2 , pp. 1-6
    • Komatsu, K.1    Miyashita, T.2    Hang, H.3
  • 10
    • 0142103820 scopus 로고    scopus 로고
    • Caspase-3-mediated cleavage of Rad9 during apoptosis
    • Lee MW, Hirai I, Wang HG, (2003) Caspase-3-mediated cleavage of Rad9 during apoptosis. Oncogene 22: 6340-6.
    • (2003) Oncogene , vol.22 , pp. 6340-6346
    • Lee, M.W.1    Hirai, I.2    Wang, H.G.3
  • 11
    • 0036241988 scopus 로고    scopus 로고
    • c-Abl Tyrosine Kinase Regulates the Human Rad9 Checkpoint Protein in Response to DNA Damage
    • Yoshida K, Komatsu K, Wang HG, Kufe D, (2002) c-Abl Tyrosine Kinase Regulates the Human Rad9 Checkpoint Protein in Response to DNA Damage. Mol Cell Biol 22: 3292-3300.
    • (2002) Mol Cell Biol , vol.22 , pp. 3292-3300
    • Yoshida, K.1    Komatsu, K.2    Wang, H.G.3    Kufe, D.4
  • 12
    • 2942691396 scopus 로고    scopus 로고
    • Human RAD9 checkpoint control/proapoptotic protein can activate transcription of p21
    • Yin Y, Zhu A, Jin YJ, Liu YX, Zhang X, et al. (2004) Human RAD9 checkpoint control/proapoptotic protein can activate transcription of p21. PNAS 101: 8864-9.
    • (2004) PNAS , vol.101 , pp. 8864-8869
    • Yin, Y.1    Zhu, A.2    Jin, Y.J.3    Liu, Y.X.4    Zhang, X.5
  • 13
    • 33644999937 scopus 로고    scopus 로고
    • Rad9, an Evolutionarily Conserved Gene With Multiple Functions for Preserving Genomic Integrity
    • Lieberman HB, (2006) Rad9, an Evolutionarily Conserved Gene With Multiple Functions for Preserving Genomic Integrity. J Cell Biochem 97: 690-697.
    • (2006) J Cell Biochem , vol.97 , pp. 690-697
    • Lieberman, H.B.1
  • 14
    • 0034235463 scopus 로고    scopus 로고
    • Structure-based predictions of Rad1, Rad9, Hus1 and Rad17 participation in sliding clamp and clamp-loading complexes
    • Venclovas C, Thelen MP, (2000) Structure-based predictions of Rad1, Rad9, Hus1 and Rad17 participation in sliding clamp and clamp-loading complexes. Nucleic Acids Res 28: 2481-2493.
    • (2000) Nucleic Acids Res , vol.28 , pp. 2481-2493
    • Venclovas, C.1    Thelen, M.P.2
  • 15
    • 67649111979 scopus 로고    scopus 로고
    • Crystal structure of the rad9-rad1-hus1 DNA damage checkpoint complex - implications for clamp loading and regulation
    • Doré AS, Kilkenny ML, Rzechorzek NJ, Pearl LH, (2009) Crystal structure of the rad9-rad1-hus1 DNA damage checkpoint complex - implications for clamp loading and regulation. Mol Cell 34 (6): 735-45.
    • (2009) Mol Cell , vol.34 , Issue.6 , pp. 735-745
    • Doré, A.S.1    Kilkenny, M.L.2    Rzechorzek, N.J.3    Pearl, L.H.4
  • 16
    • 67449103064 scopus 로고    scopus 로고
    • Crystal structure of the human rad9-hus1-rad1 clamp
    • Sohn SY, Cho Y, (2009) Crystal structure of the human rad9-hus1-rad1 clamp. J. Mol Biol 390: 490-502.
    • (2009) J. Mol Biol , vol.390 , pp. 490-502
    • Sohn, S.Y.1    Cho, Y.2
  • 17
    • 68949137117 scopus 로고    scopus 로고
    • Structure and functional implications of the human Rad9-Hus1-Rad1 cell cycle checkpoint complex
    • Xu M, Bai L, Gong Y, Xie W, Hang H, et al. (2009) Structure and functional implications of the human Rad9-Hus1-Rad1 cell cycle checkpoint complex. J Biol Chem 284: 20457-20461.
    • (2009) J Biol Chem , vol.284 , pp. 20457-20461
    • Xu, M.1    Bai, L.2    Gong, Y.3    Xie, W.4    Hang, H.5
  • 18
    • 0037067776 scopus 로고    scopus 로고
    • A Role of the C-terminal Region of Human Rad9 (hRad9) in Nuclear Transport of the hRad9 Checkpoint Complex
    • Hirai I, Wang HG, (2002) A Role of the C-terminal Region of Human Rad9 (hRad9) in Nuclear Transport of the hRad9 Checkpoint Complex. J. Biol Chem 277: 25722-25727.
    • (2002) J. Biol Chem , vol.277 , pp. 25722-25727
    • Hirai, I.1    Wang, H.G.2
  • 19
    • 3142772206 scopus 로고    scopus 로고
    • Human hRad1 but not hRad9 protects hHus1 from ubiquitin-proteasomal degradation
    • Hirai I, Sasak, T, Wang HG, (2004) Human hRad1 but not hRad9 protects hHus1 from ubiquitin-proteasomal degradation. Oncogene 23 (30): 5124-30.
    • (2004) Oncogene , vol.23 , Issue.30 , pp. 5124-5130
    • Hirai, I.1    Sasak, T.2    Wang, H.G.3
  • 20
    • 34247334687 scopus 로고    scopus 로고
    • An essential role for Drosophila hus1 in somatic and meiotic DNA damage responses
    • Abdu U, Klovstad M, Butin-Israeli V, Bakhrat A, Schüpbach T, (2007) An essential role for Drosophila hus1 in somatic and meiotic DNA damage responses. J. Cell Science 120: 1042-1049.
    • (2007) J. Cell Science , vol.120 , pp. 1042-1049
    • Abdu, U.1    Klovstad, M.2    Butin-Israeli, V.3    Bakhrat, A.4    Schüpbach, T.5
  • 21
    • 68349100144 scopus 로고    scopus 로고
    • The Drosophila hus1 gene is required for homologous recombination repair during meiosis
    • Peretz G, Gur-Arie L, Bakhrat A, Abdu U, (2009) The Drosophila hus1 gene is required for homologous recombination repair during meiosis. Mech Dev 126 (8-9): 677-86.
    • (2009) Mech Dev , vol.126 , Issue.8-9 , pp. 677-686
    • Peretz, G.1    Gur-Arie, L.2    Bakhrat, A.3    Abdu, U.4
  • 22
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real- time quantitative PCR and the 2-ΔΔCT method
    • Livak KJ, Schmittgen TD, (2001) Analysis of relative gene expression data using real- time quantitative PCR and the 2-ΔΔCT method. Methods 25: 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 23
    • 0027105007 scopus 로고
    • A knowledge base for predicting protein localization sites in eukaryotic cells
    • Nakai K, Kanehisa M, (1992) A knowledge base for predicting protein localization sites in eukaryotic cells. Genomics 14 (4): 897-911.
    • (1992) Genomics , vol.14 , Issue.4 , pp. 897-911
    • Nakai, K.1    Kanehisa, M.2
  • 24
    • 36849090938 scopus 로고    scopus 로고
    • NHK-1 phosphorylates BAF to allow karyosome formation in the Drosophila oocyte nucleus
    • Lancaster OM, Cullen CF, Ohkura H, (2007) NHK-1 phosphorylates BAF to allow karyosome formation in the Drosophila oocyte nucleus. J Cell Biol 179: 817-824.
    • (2007) J Cell Biol , vol.179 , pp. 817-824
    • Lancaster, O.M.1    Cullen, C.F.2    Ohkura, H.3
  • 25
    • 78449243967 scopus 로고    scopus 로고
    • The meiotic recombination checkpoint suppresses NHK-1 kinase to prevent reorganisation of the oocyte nucleus in Drosophila
    • Lancaster OM, Breuer M, Cullen CF, Ito T, Ohkura H, (2010) The meiotic recombination checkpoint suppresses NHK-1 kinase to prevent reorganisation of the oocyte nucleus in Drosophila. PLoS Genet 6 (10): e1001179.
    • (2010) PLoS Genet , vol.6 , Issue.10
    • Lancaster, O.M.1    Breuer, M.2    Cullen, C.F.3    Ito, T.4    Ohkura, H.5
  • 26
    • 0032168889 scopus 로고    scopus 로고
    • okra and spindle-B encode components of the RAD52 DNA repair pathway and affect meiosis and patterning in Drosophila oogenesis
    • Ghabrial A, Ray RP, Schüpbach T, (1998) okra and spindle-B encode components of the RAD52 DNA repair pathway and affect meiosis and patterning in Drosophila oogenesis. Genes Dev 12: 2711-2723.
    • (1998) Genes Dev , vol.12 , pp. 2711-2723
    • Ghabrial, A.1    Ray, R.P.2    Schüpbach, T.3
  • 27
    • 0141566666 scopus 로고    scopus 로고
    • The Drosophila spn-D gene encodes a RAD51C-like protein that is required exclusively during meiosis
    • Abdu U, Gonzalez-Reyes A, Ghabrial A, Schüpbach T, (2003) The Drosophila spn-D gene encodes a RAD51C-like protein that is required exclusively during meiosis. Genetics 165: 197-204.
    • (2003) Genetics , vol.165 , pp. 197-204
    • Abdu, U.1    Gonzalez-Reyes, A.2    Ghabrial, A.3    Schüpbach, T.4
  • 28
    • 0242556794 scopus 로고    scopus 로고
    • An essential role of DmRad51/SpnA in DNA repair and meiotic checkpoint control
    • Staeva-Vieira E, Yoo S, Lehmann R, (2003) An essential role of DmRad51/SpnA in DNA repair and meiotic checkpoint control. EMBO 22 (21): 5863-5874.
    • (2003) EMBO , vol.22 , Issue.21 , pp. 5863-5874
    • Staeva-Vieira, E.1    Yoo, S.2    Lehmann, R.3
  • 29
    • 33751318468 scopus 로고    scopus 로고
    • Drosophila mus301/spindle-C encodes a helicase with an essential role in double-strand DNA break repair and meiotic progression, Genetics
    • McCaffrey R, St Johnston D, González-Reyes A, (2006) Drosophila mus301/spindle-C encodes a helicase with an essential role in double-strand DNA break repair and meiotic progression, Genetics 174: 1273-85.
    • (2006) , vol.174 , pp. 1273-1285
    • McCaffrey, R.1    St Johnston, D.2    González-Reyes, A.3
  • 30
    • 40149090856 scopus 로고    scopus 로고
    • Drosophila brca2 Is Required for Mitotic and Meiotic DNA Repair and Efficient Activation of the Meiotic Recombination Checkpoint
    • Klovstad M, Abdu U, Schüpbach T, (2008) Drosophila brca2 Is Required for Mitotic and Meiotic DNA Repair and Efficient Activation of the Meiotic Recombination Checkpoint. PLoS Genet 4 (2): e31.
    • (2008) PLoS Genet , vol.4 , Issue.2
    • Klovstad, M.1    Abdu, U.2    Schüpbach, T.3
  • 31
    • 0033202890 scopus 로고    scopus 로고
    • Activation of a meiotic checkpoint regulates translation of Gurken during Drosophila oogenesis
    • Ghabrial A, Schüpbach T, (1999) Activation of a meiotic checkpoint regulates translation of Gurken during Drosophila oogenesis. Nat Cell Biol 1: 354-357.
    • (1999) Nat Cell Biol , vol.1 , pp. 354-357
    • Ghabrial, A.1    Schüpbach, T.2
  • 32
    • 0036795301 scopus 로고    scopus 로고
    • Activation of a meiotic checkpoint during Drosophila oogenesis regulates the translation of Gurken through Chk2/Mnk
    • Abdu U, Brodsky M, Schüpbach T, (2002) Activation of a meiotic checkpoint during Drosophila oogenesis regulates the translation of Gurken through Chk2/Mnk. Curr Biol 12 (19): 1645-1651.
    • (2002) Curr Biol , vol.12 , Issue.19 , pp. 1645-1651
    • Abdu, U.1    Brodsky, M.2    Schüpbach, T.3
  • 33
    • 27644588839 scopus 로고    scopus 로고
    • A histone code in meiosis: the histone kinase, NHK-1, is required for proper chromosomal architecture in Drosophila oocytes
    • Ivanovska I, Khandan T, Ito T, Orr-Weaver, TL, (2005) A histone code in meiosis: the histone kinase, NHK-1, is required for proper chromosomal architecture in Drosophila oocytes. Genes Dev 19: 2571-2582.
    • (2005) Genes Dev , vol.19 , pp. 2571-2582
    • Ivanovska, I.1    Khandan, T.2    Ito, T.3    Orr-Weaver, T.L.4
  • 34
    • 0032510041 scopus 로고    scopus 로고
    • Regulation of zygotic gene expression in Drosophila primordial germ cells
    • Van Doren M, Williamson AL, Lehmann R, (1998) Regulation of zygotic gene expression in Drosophila primordial germ cells. Curr Biol 8: 243-246.
    • (1998) Curr Biol , vol.8 , pp. 243-246
    • Van Doren, M.1    Williamson, A.L.2    Lehmann, R.3
  • 35
    • 0032701860 scopus 로고    scopus 로고
    • The transmembrane region of Gurken is not required for biological activity, but is necessary for transport to the oocyte membrane in Drosophila
    • Queenan AM, Barcelo G, Van Buskirk C, Schüpbach T, (1999) The transmembrane region of Gurken is not required for biological activity, but is necessary for transport to the oocyte membrane in Drosophila. Mech Dev 89: 35-42.
    • (1999) Mech Dev , vol.89 , pp. 35-42
    • Queenan, A.M.1    Barcelo, G.2    Van Buskirk, C.3    Schüpbach, T.4
  • 36
    • 0019967916 scopus 로고
    • Transposition of cloned P elements into Drosophila germ line chromosomes
    • Spradling AC, Rubin GM, (1982) Transposition of cloned P elements into Drosophila germ line chromosomes. Science 218 (4570): 341-7.
    • (1982) Science , vol.218 , Issue.4570 , pp. 341-347
    • Spradling, A.C.1    Rubin, G.M.2


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