Structure-based discovery of small molecule inhibitors targeted to protein tyrosine phosphatase 1B

Journal of Medicinal Chemistry

Volumn 43, Issue 2, 2000, Pages 146-155

  Sarmiento, Mauro ^a   Wu, Li ^a   Keng, Yen Fang ^a   Song, Li ^b   Luo, Zhaowen ^b   Huang, Ziwei ^b   Wu, Guo Zhang ^c   Yuan, Adam K ^c   Zhang, Zhong Yin ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c Tyger Scientific Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN TYROSINE PHOSPHATASE INHIBITOR;

ARTICLE; CELL FUNCTION; DRUG TARGETING; MOLECULAR INTERACTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION;

CATALYTIC DOMAIN; ENZYME INHIBITORS; KINETICS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROTEIN-TYROSINE-PHOSPHATASE; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY;

EID: 0034719423     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm990329z     Document Type: Article

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