Effects of a dietary supplement on chronic pelvic pain syndrome (Category IIIA), leucocytospermia and semen parameters

Andrologia

Volumn 44, Issue SUPPL.1, 2012, Pages 672-678

  Lombardo, F ^a   Fiducia, M ^a   Lunghi, R ^a   Marchetti, L ^a   Palumbo, A ^a   Rizzo, F ^a   Koverech, A ^b   Lenzi, A ^a   Gandini, L ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b Sigma Tau SpA   (Italy)

Author keywords

Chronic pelvic pain syndrome; Leucocytospermia; Nutraceutical; Semen analysis

Indexed keywords

ELLAGIC ACID; EPIGALLOCATECHIN GALLATE; LYCOPENE; NATURAL PRODUCT; PROXANA; SELENIUM; UNCLASSIFIED DRUG; ZINC;

ADULT; ARTICLE; CELL STRUCTURE; CONTROLLED STUDY; DIET SUPPLEMENTATION; HUMAN; LEUKOCYTE; LEUKOCYTOSPERMIA; MAJOR CLINICAL STUDY; MALE; PELVIS PAIN SYNDROME; PROSTATE SECRETION; SEMINAL PLASMA; SPERM; SPERMATOZOON ABNORMALITY; SPERMATOZOON MOTILITY;

ADULT; CHRONIC DISEASE; DIETARY SUPPLEMENTS; FEMALE; HUMANS; MALE; PELVIC PAIN; SEMEN;

EID: 84861514267     PISSN: 03034569     EISSN: 14390272     Source Type: Journal    
DOI: 10.1111/j.1439-0272.2011.01248.x     Document Type: Article

References (31)

1. Bell C, Hawthorne SJ (2008) Ellagic acid, pomegranate and prostate cancer - a mini review. Pharm Pharmacol60:139-144.
2. Calhoun EA, McNaughton Collins M, Pontari MA, O'Leary M, Leiby BE, Landis RJ, Kusek JW, Litwin MS (2004) The economic impact of chronic prostatitis. Chronic Prostatitis Collaborative Research Network. Arch Intern Med164:1231-1236.
3. Gómez Y, Arocha F, Espinoza F, Fernández D, Vásquez A, Granadillo V (2007) [Zinc levels in prostatic fluid of patients with prostate pathologies]. Invest Clin48:287-294.
4. Herzog A, Siler U, Spitzer V, Seifert N, Denelavas A, Hunziker PB, Hunziker W, Goralczyk R, Wertz K (2005) Lycopene reduced gene expression of steroid targets and inflammatory markers in normal rat prostate. FASEB J19:272-274.
5. Hong MY, Seeram NP, Heber D (2008) Pomegranate polyphenols down-regulate expression of androgen-synthesizing genes in human prostate cancer cells overexpressing the androgen receptor. J Nutr Biochem19:848-855.
6. Jang TL, Schaeffer AJ (2003) The role of cytokines in prostatitis. World J Urol21:95-99.
7. Johnson JJ, Bailey HH, Mukhtar H (2010) Green tea polyphenols for prostate cancer chemoprevention: a translational perspective. Phytomedicine17:3-13.
8. Krieger JN, Nyberg L Jr, Nickel JC (1999) NIH consensus definition and classification of prostatitis. JAMA282:236-237.
9. Krieger JN, Riley DE, Cheah PY, Liong ML, Yuen KH (2003) Epidemiology of prostatitis: new evidence for a world-wide problem. World J Urol21:70-74.
10. Kullisaar T, Türk S, Punab M, Korrovits P, Kisand K, Rehema A, Zilmer K, Zilmer M, Mändar R (2008) Oxidative stress in leucocytospermic prostatitis patients. Andrologia40:161-172.
11. Lino T, Nakahara K, Miki W, Kiso Y, Ogawa Y, Kato S, Takeuchi K (2001) Less damaging effect of whisky in rat stomachs in comparison with pure ethanol. Role of ellagic acid, the nonalcoholic component. Digestion64:214-221.
12. Liu X, Allen JD, Arnold JT, Blackman MR (2008) Lycopene inhibits IGF-I signal transduction and growth in normal prostate epithelial cells by decreasing DHT-modulated IGF-I production in cocultured reactive stromal cells. Carcinogenesis29:816-823.
13. Magri V, Perletti G, Montanari E, Marras E, Chiaffarino F, Parazzini F (2008) Chronic prostatitis and erectile dysfunction: results from a cross-sectional study. Arch Ital Urol Androl80:172-175.
14. Malik A, Mukhtar H (2006) Prostate cancer prevention through pomegranate fruit. Cell Cycle; 5:371-373.
15. McNaughton Collins M, Pontari MA, O'Leary MP, Calhoun EA, Santanna J, Landis JR, Kusek JW, Litwin MS (2001) Quality of life is impaired in men with chronic prostatitis: the Chronic Prostatitis Collaborative Research Network. J Gen Intern Med16:656-666.
16. Morgia G. (2009) Antioxidant protection and prostatic disease. Trends Med9:179-186.
17. Morgia G, Mucciardi G, Galì A, Madonia M, Marchese F, Di Benedetto A, Romano G, Bonvissuto G, Castelli T, Macchione L, Magno C (2010) Treatment of chronic prostatitis/chronic pelvic pain syndrome category IIIA with Serenoa repens plus selenium and lycopene (Profluss) versus S. repens alone: an Italian randomized multicenter-controlled study. Urol Int84:400-406.
18. Nahum A, Zeller L, Danilenko M, Prall OW, Watts CK, Sutherland RL, Levy J, Sharoni Y (2006) Lycopene inhibition of IGF-induced cancer cell growth depends on the level of cyclin D1. Eur J Nutr45:275-282.
19. Nickel JC, Alexander RB, Schaeffer AJ, Landis JR, Knauss JS, Propert KJ, Chronic Prostatitis Collaborative Research Network Study Group (2003) Leukocytes and bacteria in men with chronic prostatitis/chronic pelvic pain syndrome compared to asymptomatic controls. J Urol170:818-822.
20. Schwarz S, Obermüller-Jevic UC, Hellmis E, Koch W, Jacobi G, Biesalski HK (2008) Lycopene inhibits disease progression in patients with benign prostate hyperplasia. J Nutr138:49-53.
21. Smith KB, Pukall CF, Tripp DA, Nickel JC (2007) Sexual and relationship functioning in men with chronic prostatitis/chronic pelvic pain syndrome and their partners. Arch Sex Behav36:301-311.
22. Sohn HY, Son KH, Kwon CS, Kang SS (2004) Antimicrobial and cytotoxic activity of 18 prenylated flavonoids isolated from medicinal plants: Morualba L., Morumongolica Schneider, Broussentia papyrifera (L.) Vent Sophora flavescens Ait and Echinosophora koreensis, Nakai. Phytomedicine11:666-672.
23. Stuart EC, Scandlyn MJ, Rosengren RJ (2006) Role of epigallocatechin gallate (EGCG) in the treatment of breast and prostate cancer. Life Sci79:2329-2333.
24. Wagenlehner FM, Naber KG, Bschleipfer T, Brähler E, Weidner W (2009a) Prostatitis and male pelvic pain syndrome: diagnosis and treatment. Dtsch Arztebl Int106:175-183.
25. Wagenlehner FM, Schneider H, Ludwig M, Schnitker J, Brähler E, Weidner W. (2009b) A pollen extract (Cernilton) in patients with inflammatory chronic prostatitis-chronic pelvic pain syndrome: a multicentre, randomised, prospective, double-blind, placebo-controlled phase 3 study. Eur Urol56:544-551.
26. Wang W, Bergh A, Damber JE (2004) Chronic inflammation in benign prostate hyperplasia is associated with focal upregulation of cyclooxygenase-2, Bcl-2, and cell proliferation in the glandular epithelium. Prostate61:60-72.
27. Willis MS, Wians FH (2003) The role of nutrition in preventing prostate cancer: a review of the proposed mechanism of action of various dietary substances. Clin Chim Acta330:57-83.
28. World Health Organization (1999) WHO Manual for the Examination of Human Semen and Sperm-Cervical Mucus Interaction. Cambridge University Press, Cambridge, UK.
29. Wu D, Guo Z, Ren Z, Guo W, Meydani SN (2009) Green tea EGCG suppresses T cell proliferation through impairment of IL-2/IL-2 receptor signalling. Free Radic Biol Med47:636-643.
30. Yamamoto T, Lewis J, Wataha J, Dickinson D, Singh B, Bollag WB, Ueta E, Osaki T, Athar M, Schuster G, Hsu S (2004) Roles of catalase and hydrogen peroxide in green tea polyphenol-induced chemopreventive effects. J Pharmacol Exp Ther308:317-323.
31. Yang CS, Maliakal P, Meng X (2002) Inhibition of carcinogenesis by tea. Annu Rev Pharmacol Toxicol42:25-54.