State-of-the-art automated patch clamp devices: Heat activation, action potentials, and high throughput in ion channel screening

Frontiers in Pharmacology

Volumn 2 NOV, Issue , 2011, Pages

  Stoelzle, Sonja ^a   Obergrussberger, Alison ^a   Brüggemann, Andrea ^a   Haarmann, Claudia ^a   George, Michael ^a   Kettenhofen, Ralf ^b   Fertig, Niels ^a  

^a NANION TECHNOLOGIES GMBH   (Germany)

^b Pluriomics BV   (Germany)

Author keywords

Automated patch clamp; Current clamp; Electrophysiology; Herg; Ion channels; Nachr; Temperature control,trpv3

Indexed keywords

CALCIUM CHANNEL; ERYTHROMYCIN; ION CHANNEL; POTASSIUM CHANNEL; POTASSIUM CHANNEL HERG; SODIUM CHANNEL; VANILLOID RECEPTOR 3;

ACCURACY; ACTION POTENTIAL; ANIMAL CELL; ARTICLE; AUTOMATED PATCH CLAMP SYSTEM; AUTOMATION; CARDIOMYOCYTE DERIVED STEM CELL; CELL CULTURE; CELL DIFFERENTIATION; CELL SUSPENSION; CONTROLLED STUDY; DATA ANALYSIS SOFTWARE; DRUG ACTIVITY; DRUG POTENCY; HEAT; HEAT ACTIVATION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IC 50; MEDICAL DEVICE; MOUSE; NONHUMAN; ONLINE SYSTEM; PATCH CLAMP; RECEPTOR POTENTIAL; SAFETY; STEM CELL; THERMOREGULATION;

EID: 84861502604     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2011.00076     Document Type: Article

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