Ircinialactams: Subunit-selective glycine receptor modulators from Australian sponges of the family Irciniidae

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 8, 2010, Pages 2912-2919

  Balansa, Walter ^a   Islam, Robiul ^a   Fontaine, Frank ^a   Piggott, Andrew M ^a   Zhang, Hua ^a   Webb, Timothy I ^a   Gilbert, Daniel F ^a   Lynch, Joseph W ^a   Capon, Robert J ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Glycine receptor (GlyR) chloride channels; Glycinyl lactam sesterterpenes; Irciniidae; Marine natural products

Indexed keywords

8 HYDROXYIRCINIALACTAM A; 8 HYDROXYIRCINIALACTAM B; GLYCINE RECEPTOR; IRCINIALACTAM A; IRCINIALACTAM C; IRCINIALACTAM D; IRCINIALACTAM DERIVATIVE; LACTAM DERIVATIVE; SESTERTERPENE; UNCLASSIFIED DRUG;

ARTICLE; AUSTRALIA; CHRONIC INFLAMMATION; CHRONIC PAIN; DRUG ACTIVITY; DRUG STRUCTURE; EPILEPSY; HYPEREKPLEXIA; IRCINIIDAE; NONHUMAN; SPASTICITY; SPONGE (PORIFERA); STRUCTURE ACTIVITY RELATION;

ANIMALS; AUSTRALIA; CELL LINE; HUMANS; INDOLE ALKALOIDS; LACTAMS; PORIFERA; PROTEIN ISOFORMS; RECEPTORS, GLYCINE; STRUCTURE-ACTIVITY RELATIONSHIP;

ALGAE; INVERTEBRATA; IRCINIDAE;

EID: 77950519951     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.03.002     Document Type: Article

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