메뉴 건너뛰기




Volumn 35, Issue 5, 2012, Pages 739-749

Lycopene production from synthetic medium by Blakeslea trispora NRRL 2895 (+) and 2896 (-) in a stirred-tank fermenter

Author keywords

Blakeslea trispora; Lycopene; Scale up; Stirred tank fermenter; Synthetic medium

Indexed keywords

ABSCISIC ACID; AIR SATURATION; BLAKESLEA TRISPORA; DISSOLVED OXYGEN TENSION; FERMENTATION PROCESS; IMPELLER TIP SPEED; LYCOPENE PRODUCTION; LYCOPENES; PROCESS SCALE-UP; SCALE-UP; SCALING-UP; SHAKE FLASKS; SYNTHETIC MEDIUM;

EID: 84861472374     PISSN: 16157591     EISSN: 16157605     Source Type: Journal    
DOI: 10.1007/s00449-011-0654-4     Document Type: Article
Times cited : (28)

References (28)
  • 2
    • 40449110427 scopus 로고    scopus 로고
    • Lycopene inhibits experimental metastasis of human hepatoma SK-Hep-1 cells in athymic nude mice
    • Huang CS, Liao JW, Hu ML (2008) Lycopene inhibits experimental metastasis of human hepatoma SK-Hep-1 cells in athymic nude mice. J Nutr 138:538-543
    • (2008) J Nutr , vol.138 , pp. 538-543
    • Huang, C.S.1    Liao, J.W.2    Hu, M.L.3
  • 3
    • 49649112171 scopus 로고    scopus 로고
    • Lycopene inhibits growth of human colon cancer cells via suppression of the Akt signaling pathway
    • Tang FY, Shih CJ, Cheng LH, Ho HJ, Chen HJ (2008) Lycopene inhibits growth of human colon cancer cells via suppression of the Akt signaling pathway. Mol Nutr Food Res 52:646-654
    • (2008) Mol Nutr Food Res , vol.52 , pp. 646-654
    • Tang, F.Y.1    Shih, C.J.2    Cheng, L.H.3    Ho, H.J.4    Chen, H.J.5
  • 4
    • 0036845525 scopus 로고    scopus 로고
    • Lycopene, tomatoes, and the prevention of coronary heart disease
    • Rao AV (2002) Lycopene, tomatoes, and the prevention of coronary heart disease. Exp Biol Med 227:908-913
    • (2002) Exp Biol Med , vol.227 , pp. 908-913
    • Rao, A.V.1
  • 6
    • 33845352241 scopus 로고    scopus 로고
    • Lycopene consumption decreases oxidative stress and bone resorption markers in postmenopausal women
    • DOI 10.1007/s00198-006-0205-z
    • Rao LG, Mackinnon ES, Josse RG, Murray TM, Strauss A, Rao AV (2007) Lycopene consumption decreases oxidative stress and bone resorption markers in postmenopausal women. Osteoporosis Int 18:109-115 (Pubitemid 44885502)
    • (2007) Osteoporosis International , vol.18 , Issue.1 , pp. 109-115
    • Rao, L.G.1    Mackinnon, E.S.2    Josse, R.G.3    Murray, T.M.4    Strauss, A.5    Rao, A.V.6
  • 7
    • 0032710872 scopus 로고    scopus 로고
    • Modulation of human T-lymphocyte functions by the consumption of carotenoid-rich vegetables
    • Watzl B, Bub A, Brandstetter BR, Rechkemmer G (1999) Modulation of human T-lymphocyte functions by the consumption of carotenoid-rich vegetables. British J Nutr 82:383-389 (Pubitemid 29531268)
    • (1999) British Journal of Nutrition , vol.82 , Issue.5 , pp. 383-389
    • Watzl, B.1    Bub, A.2    Brandstetter, B.R.3    Rechkemmer, G.4
  • 8
    • 80052098436 scopus 로고    scopus 로고
    • Advance on the production of lycopene by microbial fermentation
    • In Chinese
    • Liu QN, Zhu LW, Wang YH, Li DS, Wan DJ, Tang YJ (2009) Advance on the production of lycopene by microbial fermentation. Food Ferment Ind 35(6):157-161 (In Chinese)
    • (2009) Food Ferment Ind , vol.35 , Issue.6 , pp. 157-161
    • Liu, Q.N.1    Zhu, L.W.2    Wang, Y.H.3    Li, D.S.4    Wan, D.J.5    Tang, Y.J.6
  • 9
    • 0037478973 scopus 로고    scopus 로고
    • Mutants and intersexual heterokaryons of Blakeslea trispora for production of β-carotene and lycopene
    • DOI 10.1128/AEM.69.7.4043-4048.2003
    • Mehta BJ, Obraztsova IN, Cerdá-Olmedo E (2003) Mutants and intersexual heterokaryons of Blakeslea trispora for production of β-carotene and lycopene. Appl Environ Microbiol 69:4043-4048 (Pubitemid 36870065)
    • (2003) Applied and Environmental Microbiology , vol.69 , Issue.7 , pp. 4043-4048
    • Mehta, B.J.1    Obraztsova, I.N.2    Cerda-Olmedo, E.3
  • 10
    • 84861473049 scopus 로고
    • Microbiological process for the production of lycopene
    • US patent 3,467,579
    • Bianchi ML, Francheschi G, Marnati MP, Spalla C (1969) Microbiological process for the production of lycopene. US patent 3,467,579
    • (1969)
    • Bianchi, M.L.1    Francheschi, G.2    Marnati, M.P.3    Spalla, C.4
  • 14
    • 22844452835 scopus 로고    scopus 로고
    • Construction of lycopene-overproducing E. coli strains by combining systematic and combinatorial gene knockout targets
    • DOI 10.1038/nbt1083
    • Alper H, Miyaoku K, Stephanopoulos G (2005) Construction of lycopene-overproducing E. coli strains by combining systematic and combinatorial gene knockout targets. Nat Biotechnol 23(5): 612-616 (Pubitemid 41724901)
    • (2005) Nature Biotechnology , vol.23 , Issue.5 , pp. 612-616
    • Alper, H.1    Miyaoku, K.2    Stephanopoulos, G.3
  • 15
    • 38849181168 scopus 로고    scopus 로고
    • Use of metabolic stimulators and inhibitors for enhanced production of β-carotene and lycopene by Blakeslea trispora NRRL 2895 and 2896
    • DOI 10.1016/j.biortech.2007.05.051, PII S0960852407004713
    • Choudhari SM, Ananthanarayan L, Singhal RS (2008) Use of metabolic stimulators and inhibitors for enhanced production of β-carotene and lycopene by Blakeslea trispora NRRL 2895 and 2896. Bioresour Technol 99:3166-3173 (Pubitemid 351208543)
    • (2008) Bioresource Technology , vol.99 , Issue.8 , pp. 3166-3173
    • Choudhari, S.M.1    Ananthanarayan, L.2    Singhal, R.S.3
  • 16
    • 45349102364 scopus 로고    scopus 로고
    • Lycopene formation in Blakeslea trispora. Chemical aspects of a bioprocess
    • DOI 10.1016/j.tifs.2008.01.003, PII S0924224408000095
    • Mantzouridou F, Tsimidou MZ (2008) Lycopene formation in Blakeslea trispora chemical aspects of a bioprocess. Trends Food Sci Technol 19:363-371 (Pubitemid 351847696)
    • (2008) Trends in Food Science and Technology , vol.19 , Issue.7 , pp. 363-371
    • Mantzouridou, F.1    Tsimidou, M.Z.2
  • 17
    • 36049003012 scopus 로고    scopus 로고
    • Media optimization for the production of β-carotene by Blakeslea trispora: A statistical approach
    • DOI 10.1016/j.biortech.2007.01.044, PII S0960852407001125
    • Choudhari S, Singhal R (2008) Media optimization for the production of β-carotene by Blakeslea trispora: a statistical approach. Bioresour Technol 99:722-730 (Pubitemid 350088462)
    • (2008) Bioresource Technology , vol.99 , Issue.4 , pp. 722-730
    • Choudhari, S.1    Singhal, R.2
  • 18
    • 0036207604 scopus 로고    scopus 로고
    • Effect of the aeration rate and agitation speed on β-carotene production and morphology of Blakeslea trispora in a stirred tank reactor: Mathematical modeling
    • DOI 10.1016/S1369-703X(01)00166-8, PII S1369703X01001668
    • Mantzouridou F, Roukas T, Kotzekidou P (2002) Effect of the aeration rate and agitation speed on β-carotene production and morphology of Blakeslea trispora in a stirred tank reactor: mathematical modeling. Biochem Eng J 10:123-135 (Pubitemid 34272912)
    • (2002) Biochemical Engineering Journal , vol.10 , Issue.2 , pp. 123-135
    • Mantzouridou, F.1    Roukas, T.2    Kotzekidou, P.3
  • 19
    • 33846785622 scopus 로고    scopus 로고
    • Role of hydrolytic enzymes and oxidative stress in autolysis and morphology of Blakeslea trispora during β-carotene production in submerged fermentation
    • DOI 10.1007/s00253-006-0666-1
    • Nanou K, Roukas T, Kotzekidou P (2007) Role of hydrolytic enzymes and oxidative stress in autolysis and morphology of Blakeslea trispora during β-carotene production in submerged fermentation. Appl Environ Microbiol 74:447-453 (Pubitemid 46204521)
    • (2007) Applied Microbiology and Biotechnology , vol.74 , Issue.2 , pp. 447-453
    • Nanou, K.1    Roukas, T.2    Kotzekidou, P.3
  • 20
    • 84861482448 scopus 로고    scopus 로고
    • Optimization of the mated fermentation process for the production of lycopene by Blakeslea trispora NRRL 2895 (+) and NRRL 2896 (-)
    • doi: 10.1007/s00449-011-0628-6
    • Wang JF, Liu XJ, Liu RS, Li HM, Tang YJ (2011) Optimization of the mated fermentation process for the production of lycopene by Blakeslea trispora NRRL 2895 (+) and NRRL 2896 (-). Biopro Biosys Eng. doi: 10.1007/s00449-011-0628-6
    • (2011) Biopro Biosys Eng
    • Wang, J.F.1    Liu, X.J.2    Liu, R.S.3    Li, H.M.4    Tang, Y.J.5
  • 22
    • 78650246137 scopus 로고    scopus 로고
    • Scale-up study on the fed-batch fermentation of Ganoderma lucidum for the hyperproduction of ganoderic acid and Ganoderma polysaccharides
    • Tang YJ, Zhang W, Liu RS, Zhu LW, Zhong JJ (2011) Scale-up study on the fed-batch fermentation of Ganoderma lucidum for the hyperproduction of ganoderic acid and Ganoderma polysaccharides. Process Biochem 46:404-408
    • (2011) Process Biochem , vol.46 , pp. 404-408
    • Tang, Y.J.1    Zhang, W.2    Liu, R.S.3    Zhu, L.W.4    Zhong, J.J.5
  • 23
    • 57049144759 scopus 로고    scopus 로고
    • Performance analyses of a pH-shift and DOT-shift integrated fed-batch fermentation process for the production of ganoderic acid and Ganoderma polysaccharides by medicinal mushroom Ganoderma lucidum
    • Tang YJ, Zhang W, Zhong JJ (2009) Performance analyses of a pH-shift and DOT-shift integrated fed-batch fermentation process for the production of ganoderic acid and Ganoderma polysaccharides by medicinal mushroom Ganoderma lucidum. Bioresour Technol 100:1852-1859
    • (2009) Bioresour Technol , vol.100 , pp. 1852-1859
    • Tang, Y.J.1    Zhang, W.2    Zhong, J.J.3
  • 25
    • 0342647596 scopus 로고    scopus 로고
    • Dependence of mycelial morphology on impeller type and agitation intensity
    • Jüsten P, Paul G, Nienow A, Thomas C (1996) Dependence of mycelial morphology on impeller type and agitation intensity. Biotechnol Bioeng 52:634-648
    • (1996) Biotechnol Bioeng , vol.52 , pp. 634-648
    • Jüsten, P.1    Paul, G.2    Nienow, A.3    Thomas, C.4
  • 26
    • 0031602223 scopus 로고    scopus 로고
    • Characterization of mycelial morphology using image analysis
    • Paul G, Thomas C (1998) Characterization of mycelial morphology using image analysis. Adv Biochem Eng Biotechnol 60:1-59
    • (1998) Adv Biochem Eng Biotechnol , vol.60 , pp. 1-59
    • Paul, G.1    Thomas, C.2
  • 27
    • 0026888839 scopus 로고
    • Fully-automatic measurement of mycelial morphology by image analysis
    • Tucker K, Kelly T, Delgrazia P, Thomas C (1992) Fully-automatic measurement of mycelial morphology by image analysis. Biotechnol Prog 8:353-359
    • (1992) Biotechnol Prog , vol.8 , pp. 353-359
    • Tucker, K.1    Kelly, T.2    Delgrazia, P.3    Thomas, C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.