Moraxella catarrhalis activates murine macrophages through multiple toll like receptors and has reduced clearance in lungs from TLR4 mutant mice

PLoS ONE

Volumn 7, Issue 5, 2012, Pages

  Hassan, Ferdaus ^a,c   Ren, Dabin ^a,d   Zhang, Wenhong ^a,e   Merkel, Tod J ^b   Gu, Xin Xing ^a,f  

^a NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS   (United States)

^b CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^c UNIVERSITY OF MISSOURI KANSAS CITY SCHOOL OF MEDICINE   (United States)

^d MERCER UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES   (China)

^f NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CD14 ANTIGEN; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL CLEARANCE; BACTERIAL LOAD; C3H MOUSE; CONTROLLED STUDY; CYTOKINE RELEASE; FEMALE; IN VIVO STUDY; INNATE IMMUNITY; KNOCKOUT MOUSE; MACROPHAGE ACTIVATION; MORAXELLA CATARRHALIS; MORAXELLACEAE INFECTION; MOUSE; NONHUMAN; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; ANTIGENS, CD14; CYTOKINES; FEMALE; LIPOPOLYSACCHARIDES; LUNG; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MICE, INBRED C3H; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASES; MORAXELLA (BRANHAMELLA) CATARRHALIS; MUTATION; MYELOID DIFFERENTIATION FACTOR 88; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTOR 9; TOLL-LIKE RECEPTORS;

BACTERIA (MICROORGANISMS); HAEMOPHILUS INFLUENZAE; MORAXELLA CATARRHALIS; MURINAE; MUS; NEGIBACTERIA; STREPTOCOCCUS PNEUMONIAE;

EID: 84861469609     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0037610     Document Type: Article

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