IL-7 drives Th1 and Th17 cytokine production in patients with primary SS despite an increase in cd4 t cells lacking the IL-7Rα

Rheumatology (United Kingdom)

Volumn 51, Issue 6, 2012, Pages 996-1005

  Bikker, Angela ^a   Moret, Fréderique M ^a   Kruize, Aike A ^a   Bijlsma, Johannes W J ^a   Lafeber, Floris P J G ^a   Van Roon, Joël A G ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Autoimmunity; CD25; CD4 T cells; FoxP3; IL 7; IL 7 receptor ; Primary Sj gren's syndrome; Regulatory T cells; Th1 cells (T helper 1); Th17 cells (T helper 17)

Indexed keywords

IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 7; INTERLEUKIN 7 RECEPTOR ALPHA; TRANSCRIPTION FACTOR FOXP3;

ADULT; ARTICLE; CD4+ T LYMPHOCYTE; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; PRIMARY SJOEGREN SYNDROME; PRIORITY JOURNAL; PROTEIN EXPRESSION; SJOEGREN SYNDROME; T LYMPHOCYTE ACTIVATION; TH1 CELL; TH17 CELL;

ANTIGENS, CD14; ANTIGENS, CD4; CELL PROLIFERATION; COCULTURE TECHNIQUES; EXOCRINE GLANDS; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; IMMUNE TOLERANCE; INTERLEUKIN-17; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; MALE; MIDDLE AGED; MONOCYTES; PRIMARY CELL CULTURE; RECEPTORS, INTERLEUKIN-7; SJOGREN'S SYNDROME; TH1 CELLS; TH17 CELLS;

EID: 84861465170     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/ker448     Document Type: Article

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