Toll-like receptor gene polymorphisms and preeclampsia risk: A case-control study and data synthesis

Hypertension in Pregnancy

Volumn 29, Issue 4, 2010, Pages 390-398

  Xie, Fang ^a,b   Hu, Yuxiang ^a,b   Speert, David P ^a,b   Turvey, Stuart E ^a,b   Peng, Gang ^a,b   Money, Deborah M ^a   Magee, Laura A ^a,b   Von Dadelszen, Peter ^a,b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Innate immunity; Polymorphism; Preeclampsia; TLR2; TLR4

Indexed keywords

TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4;

ADULT; ARTICLE; CASE CONTROL STUDY; CONTROLLED STUDY; DATA SYNTHESIS; FEMALE; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; HUMAN; MAJOR CLINICAL STUDY; PREECLAMPSIA; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; ALLELES; CASE-CONTROL STUDIES; FEMALE; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; IMMUNITY, INNATE; POLYMORPHISM, SINGLE NUCLEOTIDE; PRE-ECLAMPSIA; PREGNANCY; RISK; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4;

EID: 72149113780     PISSN: 10641955     EISSN: 15256065     Source Type: Journal    
DOI: 10.3109/10641950903242659     Document Type: Article

References (26)

1. Magee LA, Helewa M, Moutquin JM, von Dadelszen P, Cardew S, Côté AM, et al. Diagnosis, evaluation and management of the hypertensive disorders of pregnancy. J Obstet Gynaecol Can 2008;30(Suppl 1): S1-S48.
2. Lachmeijer AM, Dekker GA, Pals G, Aarnoudse JG, ten Kate LP, Arngrimsson R. Searching for preeclampsia genes: the current position. Eur J Obstet Gynecol Reprod Biol 2002;105(2):94-113.
3. Hallman M, Ramet M, Ezekowitz RA. Toll-like receptors as sensors of pathogens. Pediatr Res 2001;50(3):315-321.
4. Koga K, Mor G. Expression and function of toll-like receptors at the maternal-fetal interface. Reprod Sci 2008;15(3):231-242.
5. Xie F, Hu Y, Turvey SE, Magee LA, Brunham RC, Choi KC, et al. Toll-like receptors 2 and 4 and the cryopyrin inflammasome in normal pregnancy and pre-eclampsia. BJOG 2010;117:99-108 (PMID: 20002372).
6. von Dadelszen P, Magee LA, Krajden M, Alasaly K, Popovska V, Devarakonda RM, et al. Levels of antibodies against cytomegalovirus and Chlamydophila pneumoniae are increased in early onset pre-eclampsia. BJOG 2003;110(8):725-730.
7. Xie F, Hu Y, Krajden M, Magee LA, Money DM, Thomas E, et al. An association between cytomegalovirus infection and preeclampsia: case-control study and data synthesis. Acta Obstet Gynecol Scand (in press).
8. Xie F, Hu Y, Magee LA, Money DM, Patrick DM, Brunham RC, et al. Chlamydia pneumoniae infection in preeclampsia. Hypertens Pregnancy (in press).
9. Fraser R, Walker JJ, Ekbote UV, Martin KL, McShane P, Orsi NM. Interleukin-4-590 (C>T), toll-like receptor-2 +2258 (G>A) and matrix metalloproteinase-9-1562 (C>T) polymorphisms in pre-eclampsia. BJOG 2008;115(8):1052-1056.
10. Molvarec A, Jermendy A, Kovacs M, Prohaszka Z, Rigo J, Jr. Toll-like receptor 4 gene polymorphisms and preeclampsia: lack of association in a Caucasian population. Hypertens Res 2008;31(5):859-864.
11. van Rijn BB, Franx A, Steegers EA, de Groot CJ, Bertina RM, Pasterkamp G, et al. Maternal TLR4 and NOD2 gene variants, pro-inflammatory p pELLP syndrome. PLoS ONE 2008;3(4): e1865.
12. Fuchisawa A, van Eeden S, Magee LA, Whalen B, Leung PC, Russell JA, et al. Neutrophil apoptosis in preeclampsia, do steroids confound the relationship? J Obstet Gynaecol Res 2004;30(5):342-348.
13. Goswami D, Tannetta DS, Magee LA, Fuchisawa A, Redman CW, Sargent IL, et al. Excess syncytiotrophoblast microparticle shedding is a feature of early-onset pre-eclampsia, but not normotensive intrauterine growth restriction. Placenta 2006;27(1):56-61.
14. von Dadelszen P, Watson RW, Noorwali F, Marshall JC, Parodo J, Farine D, et al. Maternal neutrophil apoptosis in normal pregnancy, preeclampsia, and normotensive intrauterine growth restriction. Am J Obstet Gynecol 1999;181(2):408-414.
15. von Dadelszen P, Magee LA, Roberts JM. Subclassification of preeclampsia. Hypertens Pregnancy 2003;22(2):143-148.
16. van Rijn BB, Roest M, Franx A, Bruinse HW, Voorbij HA. Single step high-throughput determination of Toll-like receptor 4 polymorphisms. J Immunol Meth 2004;289(1-2): 81-87.
17. Kramer MS, Platt RW, Wen SW, Joseph KS, Allen A, Abrahamowicz M, et al. A new and improved population-based Canadian reference for birth weight for gestational age. Pediatrics 2001;108(2):E35.
18. Akira S, Hemmi H. Recognition of pathogen-associated molecular patterns by TLR family. Immunol Lett 2003;85(2):85-95.
19. Faas MM, Schuiling GA, Baller JF, Visscher CA, Bakker WW. A new animal model for human preeclampsia: ultra-low-dose endotoxin infusion in pregnant rats. Am J Obstet Gynecol 1994;171(1):158-164.
20. Roberts JM, Bodnar LM, Lain KY, Hubel CA, Markovic N, Ness RB, et al. Uric acid is as important as proteinuria in identifying fetal risk in women with gestational hypertension. Hypertension 2005;46(6):1263-1269.
21. Gasse P, Riteau N, Charron S, Girre S, Fick L, Petrilli V, et al. Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis. Am J Respir Crit Care Med 2009.
22. Conde-Agudelo A, Villar J, Lindheimer M. Maternal infection and risk of preeclampsia: systematic review and metaanalysis. Am J Obstet Gynecol 2008;198(1):7-22.
23. von Dadelszen P, Magee LA. Could an infectious trigger explain the differential maternal response to the shared placental pathology of preeclampsia and normotensive intrauterine growth restriction? Acta Obstet Gynecol Scand 2002;81(7):642-648.
24. von Dadelszen P, Wilkins T, Redman CW. Maternal peripheral blood leukocytes in normal and pre-eclamptic pregnancies. Br J Obstet Gynaecol 1999;106(6):576-581.
25. Beutler B. Microbe sensing, positive feedback loops, and the pathogenesis of inflammatory diseases. Immunol Rev 2009;227(1):248-263.
26. Schroder NW, Schumann RR. Single nucleotide polymorphisms of Toll-like receptors and susceptibility to infectious disease. Lancet Infect Dis 2005;5(3):156-164.