Amygdala and hippocampal volume reductions as candidate endophenotypes for borderline personality disorder: A meta-analysis of magnetic resonance imaging studies

Psychiatry Research - Neuroimaging

Volumn 201, Issue 3, 2012, Pages 245-252

  Ruocco, Anthony C ^a,b   Amirthavasagam, Sathya ^a   Zakzanis, Konstantine K ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

Author keywords

Amygdala; Borderline personality disorder; Endophenotype; Hippocampus; Magnetic resonance imaging

Indexed keywords

PSYCHOTROPIC AGENT;

AMYGDALOID NUCLEUS; BORDERLINE STATE; BRAIN SIZE; DEPRESSION; DRUG DEPENDENCE; ENDOPHENOTYPE; HIPPOCAMPUS; HUMAN; LIMBIC CORTEX; MENTAL DISEASE; MENTAL HEALTH; META ANALYSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; OUTCOME ASSESSMENT; POSTTRAUMATIC STRESS DISORDER; PRIORITY JOURNAL; REVIEW;

ADULT; AMYGDALA; BORDERLINE PERSONALITY DISORDER; FEMALE; HIPPOCAMPUS; HUMANS; MAGNETIC RESONANCE IMAGING; MALE;

EID: 84861460314     PISSN: 09254927     EISSN: 18727506     Source Type: Journal    
DOI: 10.1016/j.pscychresns.2012.02.012     Document Type: Review

References (51)

1. Almasy L., Blangero J. Endophenotypes as quantitative risk factors for psychiatric disease: rationale and study design. American Journal of Medical Genetics 2001, 105:42-44.
2. Arnone D., McIntosh A.M., Ebmeier K.P., Munafo M.R., Anderson I.M. Magnetic resonance imaging studies in unipolar depression: systematic review and meta-regression analyses. European Neuropsychopharmacology 2012, 22(1):1-16.
3. Borenstein M., Hedges L., Higgins J., Rothstein H. Comprehensive Meta-Analysis 2010, Biostat, Englewood, NJ.
4. Brambilla P., Soloff P.H., Sala M., Nicoletti M.A., Keshavan M.S., Soares J.C. Anatomical MRI study of borderline personality disorder patients. Psychiatry Research: Neuroimaging 2004, 131:125-133.
5. Bremner J.D., Randall P., Scott T.M., Bronen R.A., Seibyl J.P., Southwick S.M., Delaney R.C., McCarthy G., Charney D.S., Innis R.B. MRI-based measurement of hippocampal volume in patients with combat-related posttraumatic stress disorder. The American Journal of Psychiatry 1995, 152:973-981.
6. Bremner J.D., Randall P., Vermetten E., Staib L., Bronen R.A., Mazure C., Capelli S., McCarthy G., Innis R.B., Charney D.S. Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse - a preliminary report. Biological Psychiatry 1997, 41:23-32.
7. Bush G., Luu P., Posner M.I. Cognitive and emotional influences in anterior cingulate cortex. Trends in Cognitive Sciences 2000, 4:215-222.
8. Campbell S., Marriott M., Nahmias C., MacQueen G.M. Lower hippocampal volume in patients suffering from depression: a meta-analysis. The American Journal of Psychiatry 2004, 161:598-607.
9. Cohen J. Statistical Power Analysis for the Behavioral Sciences 1988, Lawrence Erlbaum Associates, Hillsdale, NJ.
10. Cooper H., Hedges L.V. The Handbook of Research Synthesis 1994, Russell Sage Foundation, New York, NY.
11. Distel M.A., Trull T.J., Willemsen G., Vink J.M., Derom C.A., Lynskey M., Martin N.G., Boomsma D.I. The five-factor model of personality and borderline personality disorder: a genetic analysis of comorbidity. Biological Psychiatry 2009, 66:1131-1138.
12. Driessen M., Herrmann J., Stahl K., Zwaan M., Meier S., Hill A., Osterheider M., Petersen D. Magnetic resonance imaging volumes of the hippocampus and the amygdala in women with borderline personality disorder and early traumatization. Archives of General Psychiatry 2000, 57:1115-1122.
13. Gottesman I.I., Gould T.D. The endophenotype concept in psychiatry: etymology and strategic intentions. The American Journal of Psychiatry 2003, 160:636-645.
14. Gunderson J.G. Borderline personality disorder: ontogeny of a diagnosis. The American Journal of Psychiatry 2009, 166:530-539.
15. Hall J., Olabi B., Lawrie S.M., Mcintosh A.M. Hippocampal and amygdala volumes in borderline personality disorder: a meta-analysis of magnetic resonance imaging studies. Personality and Mental Health 2010, 4:172-179.
16. Hedges L.V., Olkin I. Statistical Methods for Meta-Analysis 1985, Academic Press, New York, NY.
17. Heinrichs R.W., Zakzanis K.K. Neurocognitive deficit in schizophrenia: a quantitative review of the evidence. Neuropsychology 1998, 12:426-445.
18. Herman J.L., Perry J.C., van der Kolk B.A. Childhood trauma in borderline personality disorder. The American Journal of Psychiatry 1989, 146:490-495.
19. Hunter J.E., Schmidt F.L. Methods of meta-analysis 1990, Sage Publications, Newbury Park, CA.
20. Irle E., Lange C., Sachsse U. Reduced size and abnormal asymmetry of parietal cortex in women with borderline personality disorder. Biological Psychiatry 2005, 57:173-182.
21. Leichsenring F., Leibing E., Kruse J., New A.S., Leweke F. Borderline personality disorder. Lancet 2011, 377:74-84.
22. Lenzenweger M.F., Lane M.C., Loranger A.W., Kessler R.C. DSM-IV personality disorders in the National Comorbidity Survey Replication. Biological Psychiatry 2007, 62:553-564.
23. Lipsey M.W., Wilson D.B. The efficacy of psychological, educational, and behavioral treatment. Confirmation from meta-analysis. American Psychologist 1993, 48:1181-1209.
24. McDonald C., Zanelli J., Rabe-Hesketh S., Ellison-Wright I., Sham P., Kalidindi S., Murray R.M., Kennedy N. Meta-analysis of magnetic resonance imaging brain morphometry studies in bipolar disorder. Biological Psychiatry 2004, 56:411-417.
25. Nelson M.D., Saykin A.J., Flashman L.A., Riordan H.J. Hippocampal volume reduction in schizophrenia as assessed by magnetic resonance imaging: a meta-analytic study. Archives of General Psychiatry 1998, 55:433-440.
26. Ni X., Bismil R., Chan K., Sicard T., Bulgin N., McMain S., Kennedy J.L. Serotonin 2A receptor gene is associated with personality traits, but not to disorder, in patients with borderline personality disorder. Neuroscience Letters 2006, 408:214-219.
27. Nunes P.M., Wenzel A., Borges K.T., Porto C.R., Caminha R.M., de Oliveira I.R. Volumes of the hippocampus and amygdala in patients with borderline personality disorder: a meta-analysis. Journal of Personality Disorders 2009, 23:333-345.
28. Orwin R.G. A fail-safe N for effect size in meta-analysis. Journal of Educational Statistics 1983, 8.
29. Rodrigues E., Wenzel A., Ribeiro M.P., Quarantini L.C., Miranda-Scippa A., de Sena E.P., de Oliveira I.R. Hippocampal volume in borderline personality disorder with and without comorbid posttraumatic stress disorder: a meta-analysis. European Psychiatry 2011, 26(7):452-456.
30. Rosenthal R. Meta-analytic Procedures for Social Research 1991, Sage, Beverly Hills, CA.
31. Rosenthal R. Writing meta-analytic reviews. Psychological Bulletin 1995, 118:183-192.
32. Ruocco A.C. The neuropsychology of borderline personality disorder: a meta-analysis and review. Psychiatry Research 2005, 137:191-202.
33. Ruocco, A.C., Laporte, L., Russell, J., Guttman, H., Paris, J., submitted for publication. Response inhibition deficits in unaffected first-degree relatives of patients with borderline personality disorder. Manuscript submitted for publication.
34. Sala M., Caverzasi E., Lazzaretti M., Morandotti N., De Vidovich G., Marraffini E., Gambini F., Isola M., De Bona M., Rambaldelli G., d'Allio G., Barale F., Zappoli F., Brambilla P. Dorsolateral prefrontal cortex and hippocampus sustain impulsivity and aggressiveness in borderline personality disorder. Journal of Affective Disorders 2011, 131:417-421.
35. Schmahl C.G., Vermetten E., Elzinga B.M., Douglas Bremner J. Magnetic resonance imaging of hippocampal and amygdala volume in women with childhood abuse and borderline personality disorder. Psychiatry Research 2003, 122:193-198.
36. Schmahl C., Berne K., Krause A., Kleindienst N., Valerius G., Vermetten E., Bohus M. Hippocampus and amygdala volumes in patients with borderline personality disorder with or without posttraumatic stress disorder. Journal of Psychiatry & Neuroscience 2009, 34:289-295.
37. Siever L.J., Davis K.L. A psychobiological perspective on the personality disorders. The American Journal of Psychiatry 1991, 148:1647-1658.
38. Siever L.J., Torgersen S., Gunderson J.G., Livesley W.J., Kendler K.S. The borderline diagnosis III: identifying endophenotypes for genetic studies. Biological Psychiatry 2002, 51:964-968.
39. Steen R.G., Mull C., McClure R., Hamer R.M., Lieberman J.A. Brain volume in first-episode schizophrenia: systematic review and meta-analysis of magnetic resonance imaging studies. The British Journal of Psychiatry 2006, 188:510-518.
40. Tebartz van Elst L., Hesslinger B., Thiel T., Geiger E., Haegele K., Lemieux L., Lieb K., Bohus M., Hennig J., Ebert D. Frontolimbic brain abnormalities in patients with borderline personality disorder: a volumetric magnetic resonance imaging study. Biological Psychiatry 2003, 54:163-171.
41. Tebartz van Elst L., Ludaescher P., Thiel T., Buchert M., Hesslinger B., Bohus M., Rusch N., Hennig J., Ebert D., Lieb K. Evidence of disturbed amygdalar energy metabolism in patients with borderline personality disorder. Neuroscience Letters 2007, 417:36-41.
42. Van Horn J.D., McManus I.C. Ventricular enlargement in schizophrenia - a metaanalysis of studies of the ventricle-brain ratio (VBR). The British Journal of Psychiatry 1992, 160:687-697.
43. Videbech P., Ravnkilde B. Hippocampal volume and depression: a meta-analysis of MRI studies. The American Journal of Psychiatry 2004, 161:1957-1966.
44. Weniger G., Lange C., Sachsse U., Irle E. Reduced amygdala and hippocampus size in trauma-exposed women with borderline personality disorder and without posttraumatic stress disorder. Journal of Psychiatry & Neuroscience 2009, 34:383-388.
45. Winstanley C.A., Theobald D.E., Cardinal R.N., Robbins T.W. Contrasting roles of basolateral amygdala and orbitofrontal cortex in impulsive choice. Journal of Neuroscience 2004, 24:4718-4722.
46. Wolf F.M. Meta-analysis: Quantitative Methods for Research Synthesis 1986, Sage, London, United Kingdom.
47. Zakzanis K.K. Brain is related to behavior (p<.05). Journal of Clinical and Experimental Neuropsychology 1998, 20:419-427.
48. Zakzanis K.K., Leach L., Kaplan E. Neuropsychological Differential Diagnosis 1999, Swets & Zeitlinger, Lisse, The Netherlands.
49. Zanarini M.C., Vujanovic A.A., Parachini E.A., Boulanger J.L., Frankenburg F.R., Hennen J. Zanarini Rating Scale for Borderline Personality Disorder (ZAN-BPD): a continuous measure of DSM-IV borderline psychopathology. Journal of Personality Disorders 2003, 17:233-242.
50. Zetzsche T., Frodl T., Preuss U.W., Schmitt G., Seifert D., Leinsinger G., Born C., Reiser M., Moller H.J., Meisenzahl E.M. Amygdala volume and depressive symptoms in patients with borderline personality disorder. Biological Psychiatry 2006, 60:302-310.
51. Zetzsche T., Preuss U.W., Frodl T., Schmitt G., Seifert D., Munchhausen E., Tabrizi S., Leinsinger G., Born C., Reiser M., Moller H.J., Meisenzahl E.M. Hippocampal volume reduction and history of aggressive behaviour in patients with borderline personality disorder. Psychiatry Research: Neuroimaging 2007, 154:157-170.