Further studies on the hypothesis of PARP-1 inhibition as a strategy for lessening the long-term effects produced by perinatal asphyxia: Effects of nicotinamide and theophylline on PARP-1 activity in brain and peripheral tissue

Neurotoxicity Research

Volumn 22, Issue 1, 2012, Pages 79-90

  Allende Castro, C ^a   Espina Marchant, P ^a   Bustamante, D ^a   Rojas Mancilla, E ^a   Neira, T ^a   Gutierrez Hernandez, M A ^a   Esmar, D ^a   Valdes, J L ^a   Morales, P ^a   Gebicke Haerter, P J ^b   Herrera Marschitz, M ^a  

^a UNIVERSITY OF CHILE   (Chile)

^b CENTRAL INSTITUTE OF MENTAL HEALTH   (Germany)

Author keywords

Developmental deficits; Hypoxia; Microdialysis; Neonatal; Poly(ADP ribose) polymerase; Rats; Thigmotactics

Indexed keywords

MONOAMINE; NICOTINAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; THEOPHYLLINE;

ANIMAL BEHAVIOR; ANIMAL EUTHANASIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR CHANGE; BRAIN TISSUE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BRAIN LEVEL; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG TISSUE LEVEL; FEMALE; FETUS; HEART; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; MALE; MICRODIALYSIS; NEUROTRANSMISSION; NEWBORN; NONHUMAN; PERINATAL ASPHYXIA; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; PUP (RODENT); RAT; RESUSCITATION; SINGLE DRUG DOSE; ULTRAVIOLET SPECTROSCOPY; WATER IMMERSION;

ANIMALS; ANIMALS, NEWBORN; ASPHYXIA; ASPHYXIA NEONATORUM; BEHAVIOR, ANIMAL; BRAIN; HEART; HUMANS; INFANT, NEWBORN; MICRODIALYSIS; MODELS, ANIMAL; MYOCARDIUM; NIACINAMIDE; PHOSPHODIESTERASE INHIBITORS; POLY(ADP-RIBOSE) POLYMERASES; RATS; RATS, WISTAR; THEOPHYLLINE; VITAMIN B COMPLEX;

ANIMALIA; RATTUS;

EID: 84861458087     PISSN: 10298428     EISSN: 14763524     Source Type: Journal    
DOI: 10.1007/s12640-012-9310-2     Document Type: Article

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