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Volumn 14, Issue 3, 2012, Pages 497-510
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Methylene diphosphonate-conjugated adriamycin liposomes: Preparation, characteristics, and targeted therapy for osteosarcomas in vitro and in vivo
a
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Author keywords
Adriamycin liposomes; Methylenediphosphonate; Osteosarcomas; Targeted therapy
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Indexed keywords
ADRIAMYCIN;
AVERAGE DIAMETER;
CASPASE-3;
DEUTERATED WATER;
DRUG LOADING;
ENCAPSULATION EFFICIENCY;
EQUILIBRIUM METHODS;
IN-VITRO;
IN-VIVO;
INFRARED SPECTRUM;
LETHAL DOSE;
LOADING EFFICIENCY;
LUNG NODULE;
METHYLENEDIPHOSPHONATE;
NUDE MICE;
OSTEOSARCOMA;
OSTEOSARCOMA CELLS;
OSTEOSARCOMAS;
PARTICLE SIZE ANALYZERS;
SPRAGUE-DAWLEY RATS;
STANDALONE SYSTEMS;
SURVIVAL RATE;
TARGETED THERAPY;
THERAPEUTIC EFFECTS;
THERAPEUTIC EFFICACY;
TOXICITY ASSAYS;
TUMOR GROWTH;
ANIMALS;
BROMINE COMPOUNDS;
CELL DEATH;
DEUTERIUM;
DIALYSIS;
ENCAPSULATION;
ENZYME INHIBITION;
FLOW CYTOMETRY;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
HYDROGEN BONDS;
LOADING;
PARTICLE SIZE ANALYSIS;
RATING;
TECHNETIUM;
TOXICITY;
TRANSMISSION ELECTRON MICROSCOPY;
TUMORS;
LIPOSOMES;
3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE;
ADRIAMYCIN LIPOSOME;
ANTINEOPLASTIC AGENT;
CASPASE 3;
CYTOTOXIC AGENT;
DEUTERIUM OXIDE;
DOXORUBICIN;
MEDRONATE TECHNETIUM TC 99M;
MEDRONIC ACID;
METHYLENEDIPHOSPHONATE ADRIAMYCIN LIPOSOME CONJUGATE;
UNCLASSIFIED DRUG;
ANALYZER;
ANIMAL CELL;
ANIMAL EXPERIMENT;
ANIMAL MODEL;
ANIMAL TISSUE;
ANTINEOPLASTIC ACTIVITY;
APOPTOSIS;
ARTICLE;
CANCER COMBINATION CHEMOTHERAPY;
CANCER INHIBITION;
CANCER SURVIVAL;
CONTROLLED STUDY;
DRUG CONJUGATION;
DRUG CYTOTOXICITY;
DRUG DETERMINATION;
DRUG EFFECT;
DRUG EFFICACY;
DRUG MECHANISM;
DRUG SCREENING;
DRUG STABILITY;
DRUG STRUCTURE;
DRUG SYNTHESIS;
DRUG TISSUE LEVEL;
ENCAPSULATION;
ENZYME ACTIVITY;
EQUILIBRIUM DIALYSIS;
FEMALE;
FLOW CYTOMETRY;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
HUMAN;
HUMAN CELL;
HYDROGEN BOND;
IN VITRO STUDY;
IN VIVO STUDY;
INFRARED RADIATION;
LD 50;
LIPOSOMAL DELIVERY;
LUNG METASTASIS;
LUNG NODULE;
MALE;
MOLECULARLY TARGETED THERAPY;
MONOTHERAPY;
MOUSE;
NONHUMAN;
OSTEOSARCOMA;
OSTEOSARCOMA CELL;
PARTICLE SIZE;
PRIORITY JOURNAL;
RAT;
SURVIVAL RATE;
SUSTAINED DRUG RELEASE;
TARGET CELL DESTRUCTION;
TRANSMISSION ELECTRON MICROSCOPY;
TUMOR GROWTH;
ANIMALS;
ANTIBIOTICS, ANTINEOPLASTIC;
APOPTOSIS;
CASPASE 3;
CELL LINE, TUMOR;
DIPHOSPHONATES;
DISEASE MODELS, ANIMAL;
DOXORUBICIN;
DRUG DELIVERY SYSTEMS;
FLOW CYTOMETRY;
HUMANS;
MALE;
MICE;
MICE, INBRED BALB C;
MICE, NUDE;
MICROSCOPY, ELECTRON, TRANSMISSION;
NEOPLASM METASTASIS;
OSTEOSARCOMA;
POLYETHYLENE GLYCOLS;
RATS;
RATS, SPRAGUE-DAWLEY;
ANIMALIA;
MUS MUSCULUS;
RATTUS;
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EID: 84861456394
PISSN: 13872176
EISSN: 15728781
Source Type: Journal
DOI: 10.1007/s10544-011-9626-3 Document Type: Article |
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Times cited : (23)
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References (44)
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