186Re-liposome labeling using 186Re-SNS/S complexes: In vitro stability, imaging, and biodistribution in rats

Journal of Nuclear Medicine

Volumn 44, Issue 12, 2003, Pages 1992-1999

  Bao, Ande ^a   Goins, Beth ^a   Klipper, Robert ^a   Negrete, George ^b   Phillips, William T ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b UNIVERSITY OF TEXAS AT SAN ANTONIO   (United States)

Author keywords

186Re; Biodistribution; Liposomes; Radiolabeling; Radionuclide therapy; SNS S complexes

Indexed keywords

AMMONIUM SULFATE; BENZENE; CYSTEINE; LIGAND; LIPOSOME; N,N BIS(2 MERCAPTOETHYL) N',N' DIETHYLENEDIAMINE; RADIOISOTOPE; RHENIUM 186; SODIUM CHLORIDE; THIOL; UNCLASSIFIED DRUG; RADIOPHARMACEUTICAL AGENT; RHENIUM;

ARTICLE; BIOACCUMULATION; BLOOD SAMPLING; CONTROLLED STUDY; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG SPECIFICITY; DRUG STABILITY; IMAGING SYSTEM; IN VITRO STUDY; IN VIVO STUDY; INCUBATION TIME; ISOMER; ISOTOPE LABELING; MICROENCAPSULATION; NONHUMAN; NUCLEAR MEDICINE; PH MEASUREMENT; PRIORITY JOURNAL; RADIOACTIVITY; RAT; SPLEEN; ANIMAL; ANTIBODY SPECIFICITY; BLOOD; CHEMISTRY; MALE; METABOLIC CLEARANCE RATE; METHODOLOGY; SPRAGUE DAWLEY RAT; SYNTHESIS; TISSUE DISTRIBUTION;

AMMONIUM SULFATE; ANIMALS; CYSTEINE; DRUG STABILITY; ISOTOPE LABELING; LIPOSOMES; MALE; METABOLIC CLEARANCE RATE; ORGAN SPECIFICITY; RADIOISOTOPES; RADIOPHARMACEUTICALS; RATS; RATS, SPRAGUE-DAWLEY; RHENIUM; TISSUE DISTRIBUTION;

EID: 1542681644     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Lasic DD, Papahadjopoulos D, eds. Medical Applications of Liposomes. Amsterdam, The Netherlands Elsevier; 1998 15-449
2. Drummond DC, Meyer O, Hong K, Kirpotin DB, Papahadjoupolos D Optimizing liposomes for delivery of chemotherapeutic agents to solid tumors. Pharmacol Rev. 1999;51:691-743.
3. Pietrobon PJ. Liposome design and vaccine development. Pharm Biotechnol. 1995;6.347-361.
4. Lasic DD. Liposomes in Gene Therapy. Boca Raton, FL: CRC Press. 1997;67-197.
5. Hope MJ, Bally MB, Webb G, Cullis PR Production of large unilamellar vesicles by a rapid extrusion procedure, characterization of size distribution, trapped volume and ability to maintain a membrane potential. Biochim Biophys Acta 1985,812 55-65.
6. Oku N Anticancer therapy using glucuronate modified long-circulating liposomes. Adv Drug Deliv Rev. 1999;40:63-73.
7. Wang S, Low PS. Folate-mediated targeting of antineoplastic drugs, imaging agents, and nucleic acids to cancer cells. J Control Release 1998,53 39-48.
8. Willis MC, Collins B, Zhang T, et al. Liposome-anchored vascular endothelial growth factor aptamers. Bioconjug Chem 1998.9 573-582.
9. Phillips WT, Klipper R, Goins B. Novel method of greatly enhanced delivery of liposomes to lymph nodes. J Pharmacol Exp Ther 2000,295:309-313.
10. Thierens HM, Monsieurs MA. Brans B, et al. Dosimetry from organ to cellular dimensions. Comput Med Imaging Graph. 2001;25:187-193.
11. Matteucci ML, Anyaramdhatla G, Rosner G. et al Hyperthermia increases accumulation of technetium-99m-labeled liposomes in feline sarcomas. Clin Cancer Res. 2000,6:3748-3755
12. Koukourakis MI, Koukouraki S, Giatromanolaki A, et al. High intratumoral accumulation of stealth liposomal doxorubicin in sarcomas: rationale for combination with radiotherapy Acta Oncol. 2000;39:207-211.
13. Phillips WT. Rudolph AS. Goins B. Timmons JH, Klipper R, Blumhardt R. A simple method for producing a technetium-99m-labeled liposome, which is stable in vivo. Nucl Med Biol 1992;19:539-547.
14. 67Gallium-labeled liposomes with prolonged circulation: preparation and potential as nuclear imaging agents. Nucl Med Biol 1993;20:149-155.
15. 34-bound inulin. Biochim Biophys Acta. 1988;944:329-336.
16. Oku N Delivery of contrast agents for positron emission tomography imaging by liposomes. Adv Drug Deliv Rev 1999;37:53-61.
17. Goins B, Klipper R, Rudolph AS, Cliff RO, Blumhardt R, Phillips WT Biodistribution and imaging studies of technetium-99m-labeled liposomes in rats with focal infection J Nucl Med 1993;34:2160-2168.
18. Goins B, Klipper R, Rudolph AS, Phillips WT. Use of technetium-99m- liposomes in tumor imaging. J Nucl Med. 1994;35:1491-1498.
19. Semple SC, Chonn A, Cullis PR. Influence of cholesterol on the association of plasma proteins with liposomes. Biochemistry, 1986;35:2521-2525.
20. Emfietzoglou D, Kostarelos K, Sgouros G. An analytic dosimetry study for the use of radionuclide-liposome conjugates in internal radiotherapy. J Nucl Med 2001;42:499-504.
21. Goins B, Phillips WT, Klipper R. Blood-pool imaging using technetium-99m-labeled liposomes. J Nucl Med. 1996,37,1374-1379.
22. Boerman OC, Oyen WJ, van Bloois L, et al. Optimization of technetium-99m-labeled PEG liposomes to image focal infection: effects of particle size and circulation time. J Nucl Med 1997,38:489-493.
23. Harrington KJ, Rowlinson-Busza G, Syrigos N, Uster PS, Vile RG, Stewart JSW. Pegylated liposomes have potential as vehicles for intratumoral and subcutaneous drug delivery. Clin Cancer Res. 2000;6:2528-2537
24. 188Re-Liposome radiolabeling for nuclear imaging and targeted radionuclide therapy. In: Nicolini M, Mazzi IJ, eds Technetium, Rhenium and Other Metals in Chemistry and Nuclear Medicine, 6 Padova, Italy SGE; 2002:381-386.
25. Mastrostamatis SG, Papadopoulos MS. Pirmettis IC, et al. Tridentate ligands containing the SNS donor atom set as a novel backbone or the development of technetium brain-imaging agents. J Med Chem. 1994;37:3212-3218.
26. Pirmettis IC, Papadopoulos MS, Mastrostamatis CP, Raptopoulou CP, Terzis A, Chiotellis E. Synthesis and characterization of oxotechnetium(V) mixed-ligand complexes containing a tridentate N-substituted bis(2-mercaptoethyl) amine and a monodentate thiol Inorg Chem 1996;35:1685-1691.
27. Pelecanou M, Pirmettis IC, Papadopoulos MS, Terzis A, Chiotellis E, Stassinopoulou CI. Structural studies of ReO(V) mixed ligand [SNS][CI] and [SNS][S] complexes Inorg Chim Acta. 1999;287:142-151.
28. Maurer-Spurej E, Wong KF, Maurer N, Fenske DB, Cullis PR. Factors influencing uptake and retention of amino-containing drugs in large unilamellar vesicles exhibiting transmembrane pH gradients. Biochim Biophys Acta. 1999,1416:1-10.
29. Stewart JCM. Colorimetric determination of phospholipids with ammonium ferrothiocyanate. Anal Biochem. 1980;104:10-14.
30. 2- core. Inorg Chim Acta. 1984;90:41-51.
31. Petty C Research Techniques in the Rat. Springfield, IL Charles C. Thomas, 1982 66-70.
32. Frank DW. Physiological data of laboratory animals. In Mclby EC Jr, Altman NH, eds. Handbook of Laboratory Animal Science. Vol. III. Boca Raton, FL: CRC Press; 1976 23-64.
33. 188Re incorporated in liposomes suitable for radiotherapy. Nucl Med Biol 1991;18:449-454
34. Tilcock C Delivery of contrast agents for magnetic resonance imaging, computed tomography, nuclear medicine and ultrasound. Adv Drug Deliv Rev. 1999;37 33-51
35. Hung JC, Corlija M, Volkerr WA, Holmes RA. Kinetic analysis of technetium-99m d,l-HMPAO decomposition in aqueous media. J Nucl Med. 1988;29 1568-1576
36. Utkhede D. Yeh V, Szucs M. Tilcock C Uptake of yttrium-90 into lipid vesicles J Liposome Res. 1994;4:1049-1061
37. Kutzner J, Becker M, Grimm W. Bone-seeking behavior of rhenium and yttrium complexes [in German]. Nuklearmedizin. 1983,22.162-165.
38. Weber DA. Eckerman KF, Dillman LT, Ryman JC. MIRD: Radionuclide Data and Decay Schemes. Reston. VA: Society of Nuclear Medicine: 1989.159
39. Nock BA, Mama T, Yannoukakos D, Pirmettis IC, Papadopoulos MS, Chiotellis E Glutathione-mediated metabolism of technetium-99m SNS/S mixed ligand complexes: a proposed mechanism of brain retention. J Med Chem 1999;42:1066-1075
40. Nomura T, Korceda N, Yamashita F, Takakura Y, Hashida M Effect of particle size and charge on the disposition of lipid carriers after intratumoral injection into tissue-isolated tumors. Pharm Res 1998;151:128-132.