Taraxerone enhances alcohol oxidation via increases of alcohol dehyderogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities and gene expressions

Food and Chemical Toxicology

Volumn 50, Issue 7, 2012, Pages 2508-2514

  Sung, Chang Keun ^a   Kim, Seung Mi ^b   Oh, Chang Jin ^a   Yang, Sun A ^b   Han, Byung Hee ^b   Mo, Eun Kyoung ^b  

^a Chungnam National University   (South Korea)

^b DBIO Incorporation   (South Korea)

Author keywords

Acetaldehyde dehydrogenase (ALDH); Alcohol dehydrogenase (ADH); Catalase; Sedum sarmentosum; Taraxerone

Indexed keywords

ALCOHOL; ALCOHOL DEHYDROGENASE; ALDEHYDE DEHYDROGENASE; CATALASE; GLUTATHIONE; SUPEROXIDE DISMUTASE; TARAXERONE;

ALCOHOL BLOOD LEVEL; ALCOHOL OXIDATION; ALCOHOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CRASSULACEAE; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; GENE EXPRESSION; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SEDUM SARMENTOSUM;

ALCOHOL DEHYDROGENASE; ALCOHOLS; ALDEHYDE OXIDOREDUCTASES; ANIMALS; BASE SEQUENCE; DNA PRIMERS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; MICE; OLEANOLIC ACID; OXIDATION-REDUCTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

MUS; SEDUM SARMENTOSUM;

EID: 84861441570     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.04.031     Document Type: Article

References (27)

1. Ahmed Y., Sohrab M.H., Al-Reza S.M., Tareq F.S., Hasan C.M., Sattar M.A. Antimicrobial and cytotoxic constituents from leaves of Sapium baccatum. Food Chem. Toxicol. 2010, 48:549-552.
2. Arteel G.E. Oxidants and antioxidants in alcohol-induced liver disease. Gastroenterol 2003, 124:778-790.
3. Cederbaum A.I., Dicker E., Rubin E., Cohen G. The effect of dimethylsulfoxide and other hydroxyl radical scavengers on the oxidation of ethanol by rat liver microsomes. Biochem. Biophys. Res. Commun. 1977, 78:1254-1262.
4. Corlett J.L., Clegg M.S., Keen C.L., Grivetti L.E. Mineral content of culinary and medicinal plants by Hmong refugees living in Sacramento, California. Int. J. Food Sci. Nutr. 2002, 53:117-128.
5. Gachet M.S., Kunert O., Kaiser M., Brun R., Zehl M., Keller W., Munoz R.A., Bauer R., Schuehly W. Antiparasitic compounds from Cupania cinerea with activities against Plasmodium falciparum and Trypanosoma brucei rhodesiense. J. Nat. Prod. 2011, 74:559-566.
6. Institute of Laboratory Animal Research, Commission of Life Sciences, & National Research Council Guide for the Care and Use of Laboratory Animals 2010, The National Academy Press, Washington, DC. 8th ed.
7. Khanal T., Choi J.H., Hwang Y.P., Chung Y.C., Jeong H.G. Saponins isolated from the root of Platycodon grandiflorum protect against acute ethanol-induced hepatotoxicity in mice. Food Chem. Toxicol. 2009, 47:530-535.
8. Kim K.H., Chung Y.T., Lee J.H., Park Y.S., Shin M.K., Kim H.S., Kim D.H., Lee H.Y. Hepatic detoxification activity and reduction of serum alcohol concentration of Hovenia dulcis Thunb from Korea and China. Korean J. Med. Crop Sci. 2000, 8:225-233.
9. Kuljanabhagavad T., Suttisri R., Pengsuparp T., Ruangrungsi N. Chemical structure and antiviral activity of aerial part from Laggera pterodonta. J. Health Res. 2009, 23:175-177.
10. Lee H., Senevirathne M., Kim J., Kim Y., Lee M., Jeong M., Kang Y.M., Kim J.I., Nam B., Ahn C., Je J. Protective effect of fermented sea tangle against ethanol and carbon tetrachloride-induced hepatic damage in Sprague-Dawley rats. Food Chem. Toxicol. 2010, 48:1123-1128.
11. Li G., Ye Y., Kang J., Yao X., Zhang Y., Jiang W., Gao M., Dai Y., Xin Y., Wang Q., Yin Z., Luo L. l-Theanine prevents alcoholic liver injury through enhancing the antioxidant capability of hepatocytes. Food Chem. Toxicol. 2012, 50:363-372.
12. Lieberman H.R., Bathalon G.P., Falco C.M., Kramer F.M., Morgan C.A., Niro P. Severe decrements in cognition function and mood induced by sleeploss, heat, dehydration, and undernutrition during simulated combat. Biol. Psychiatry 2005, 57:422-429.
13. Liu B., Du J., Zeng J., Chen C., Niu S. Characterization and antioxidant activity of dihydromyricetin-lecithin complex. Eur. Food Res. Technol. 2009, 230:325-331.
14. Manríquez-Torres J.J., Zúñiga-Estrada A., González-Ledesma M., Torres-Valencia1 J.M. The antibacterial metabolites and proacacipetalin from Acacia cochliacantha. J. Mex. Chem. Soc. 2007, 51:228-231.
15. Mo E.K., Han B.H., Kim S.M., Yang S.A., Kang S.K., Oh C.J., Kim R., Kim C.G., Kang H.J., Sung C.K. Identification of d-friedoolean-13-en-3-one (taraxerone) as an antioxidant compound from Sedum sarmentosum. Food Sci. Biotechnol. 2012, 21:485-490.
16. Mo E.K., Kim H.H., Kim S.M., Cho H.H., Sung C.K. Production of sedum extract adding jelly and assessment of its physicochemical properties. Korean J. Food Sci. Technol. 2007, 39:619-624.
17. Moulisha B., Bikash M.N., Partha P., Kumar G.A., Sukdeb B., Kanti H.P. In vitro anti-leishmanial and anti-tumour activities of a pentacyclic triterpenoid compound isolated from the fruits of Dregea volubilis Benth Asclepiadaceae. Trop. J. Pharm. Res. 2009, 8:127-131.
18. Pittler M.H., Verster J.C., Ernst E. Interventions for preventing or treating alcohol hangover: systematic review of randomised controlled trials. Br. Med. J. 2005, 331:1515-1518.
19. Setzer W.N., Shen X., Bates R.B., Burns J.R., McClure K.J., Zhang P., Moriarity D.M., Lawton R.O. A phytochemical investigation of Alchornea latifolia. Fitoterapia 2000, 71:195-198.
20. Shen Y., Lindemeyer K., Gonzalez C., Shao X.M., Spingelman I., Olsen R.W., Liang J. Dihydromyricetin as a novel anti-alcohol intoxication medication. J. Neurosci. 2012, 32:390-401.
21. Spanova M., Daum G. Squalene-biochemistry, molecular biology, process biotechnology, and applications. Eur. J. Lipid Sci. Technol. 2011, 113:1299-1320.
22. Szuster-Ciesielska A., Kandefer-Szerszen M. Protective effects of betulin and betulinic acid against ethanol-induced cytotoxicity in HepG2 cells. Pharmacol. Report 2005, 57:588-595.
23. Varughes T., Manir M.M., Rahaman M., Kim J.K., Lee B.G., Moo S.S. Tea triterpenoidal saponins from the roots of Camellia sinensis have inhibitory effects against alcohol dehydrogenase. Planta Med. 2011, 77:2029-2036.
24. Wang X.G. Isolation, structure identification and insecticidal activity of compounds from Ficus tsiangii Merr. ex Corner. Acta Entomol. Sinica 2010, 53:525-530.
25. Yan Y., Yang J., Mou Y., Wang L., Zhou Y., Wu C. Differences in the activities of resveratrol and ascorbic acid in protection of ethanol-induced oxidative DNA damage in human peripheral lymphocytes. Food Chem. Toxicol. 2012, 50:168-174.
26. Yin H., Choi Y., Kim Y., Sohn D., Ryu S., Lee B. Salvia miltiorrhiza Bunge and its active component cryptotanshinone protects primary cultured rat hepatocytes from acute ethanol-induced cytotoxicity and fatty infiltration. Food Chem. Toxicol. 2009, 47:98-103.
27. Yoo S.M., Mun S., Kim J.H. Recovery and pre-purification of (+)-dihydromyricetin from Hovenia dulcis. Process Biochem. 2006, 41:567-570.