메뉴 건너뛰기




Volumn 7, Issue 4, 2004, Pages 364-372

The X-linked mental retardation protein oligophrenin-1 is required for dendritic spine morphogenesis

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; COMPLEMENTARY RNA; ENZYME ACTIVATOR; GENE PRODUCT; OLIGOPHRENIN 1; PROTEIN HOMER; RHO GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

EID: 1842455769     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/nn1210     Document Type: Article
Times cited : (250)

References (50)
  • 1
    • 0035464960 scopus 로고    scopus 로고
    • Monogenic causes of X-linked mental retardation
    • Chelly, J. & Mandel, J.L. Monogenic causes of X-linked mental retardation. Nat. Rev. Genet. 2, 669-680 (2001).
    • (2001) Nat. Rev. Genet. , vol.2 , pp. 669-680
    • Chelly, J.1    Mandel, J.L.2
  • 2
    • 0036948994 scopus 로고    scopus 로고
    • X-linked mental retardation: Vanishing boundaries between non-specific (MRX) and syndromic (MRXS) forms
    • Frints, S.G., Froyen, G., Marynen, P. & Fryns, J.P. X-linked mental retardation: vanishing boundaries between non-specific (MRX) and syndromic (MRXS) forms. Clin. Genet. 62, 423-432 (2002).
    • (2002) Clin. Genet. , vol.62 , pp. 423-432
    • Frints, S.G.1    Froyen, G.2    Marynen, P.3    Fryns, J.P.4
  • 3
    • 0036543312 scopus 로고    scopus 로고
    • Rho proteins, mental retardation and the cellular basis of cognition
    • Ramakers, G.J. Rho proteins, mental retardation and the cellular basis of cognition. Trends Neurosci. 25, 191-199 (2002).
    • (2002) Trends Neurosci. , vol.25 , pp. 191-199
    • Ramakers, G.J.1
  • 4
    • 0030968580 scopus 로고    scopus 로고
    • Rho GTPases and network signaling
    • Van Aelst, L. & D'Souza-Schorey, C. Rho GTPases and network signaling. Genes Dev. 11, 2295-2322 (1997).
    • (1997) Genes Dev. , vol.11 , pp. 2295-2322
    • Van Aelst, L.1    D'Souza-Schorey, C.2
  • 5
    • 0034574572 scopus 로고    scopus 로고
    • Rho GTPases in neuronal morphogenesis
    • Luo, L. Rho GTPases in neuronal morphogenesis. Nat. Rev. Neurosci. 1, 173-180 (2000).
    • (2000) Nat. Rev. Neurosci. , vol.1 , pp. 173-180
    • Luo, L.1
  • 6
    • 0034661746 scopus 로고    scopus 로고
    • Small GTPases Rac and Rho in the maintenance of dendritic spines and branches in hippocampal pyramidal neurons
    • Nakayama, A.Y., Harms, M.B. & Luo, L. Small GTPases Rac and Rho in the maintenance of dendritic spines and branches in hippocampal pyramidal neurons. J. Neurosci. 20, 5329-5338 (2000).
    • (2000) J. Neurosci. , vol.20 , pp. 5329-5338
    • Nakayama, A.Y.1    Harms, M.B.2    Luo, L.3
  • 7
    • 0033807686 scopus 로고    scopus 로고
    • Regulation of dendritic spine morphology by the rho family of small GTPases: Antagonistic roles of Rac and Rho
    • Tashiro, A., Minden, A. & Yuste, R. Regulation of dendritic spine morphology by the rho family of small GTPases: antagonistic roles of Rac and Rho. Cereb. Cortex 10, 927-938 (2000).
    • (2000) Cereb. Cortex , vol.10 , pp. 927-938
    • Tashiro, A.1    Minden, A.2    Yuste, R.3
  • 8
    • 0032580161 scopus 로고    scopus 로고
    • Oligophrenin-1 encodes a rhoGAP protein involved in X-linked mental retardation
    • Billuart, P. et al. Oligophrenin-1 encodes a rhoGAP protein involved in X-linked mental retardation. Nature 392, 923-926 (1998).
    • (1998) Nature , vol.392 , pp. 923-926
    • Billuart, P.1
  • 9
    • 0031710557 scopus 로고    scopus 로고
    • PAK3 mutation in nonsyndromic X-linked mental retardation
    • Allen, K.M. et al. PAK3 mutation in nonsyndromic X-linked mental retardation. Nat. Genet. 20, 25-30 (1998).
    • (1998) Nat. Genet. , vol.20 , pp. 25-30
    • Allen, K.M.1
  • 10
    • 0033775672 scopus 로고    scopus 로고
    • Mutations in ARHGEF6, encoding a guanine nucleotide exchange factor for Rho GTPases, in patients with X-linked mental retardation
    • Kutsche, K. et al. Mutations in ARHGEF6, encoding a guanine nucleotide exchange factor for Rho GTPases, in patients with X-linked mental retardation. Nat. Genet. 26, 247-250 (2000).
    • (2000) Nat. Genet. , vol.26 , pp. 247-250
    • Kutsche, K.1
  • 11
    • 0043162110 scopus 로고    scopus 로고
    • The RhoGAP activity of OPHN1, a new F-actin-binding protein is negatively controlled by its amino-terminal domain
    • Fauchereau, F. et al. The RhoGAP activity of OPHN1, a new F-actin-binding protein is negatively controlled by its amino-terminal domain. Mol. Cell. Neurosci. 23, 574-586 (2003).
    • (2003) Mol. Cell. Neurosci. , vol.23 , pp. 574-586
    • Fauchereau, F.1
  • 12
    • 0035654078 scopus 로고    scopus 로고
    • Dendritic spines: Structure, dynamics and regulation
    • Hering, H. & Sheng, M. Dendritic spines: structure, dynamics and regulation. Nat. Rev. Neurosci. 2, 880-888 (2001).
    • (2001) Nat. Rev. Neurosci. , vol.2 , pp. 880-888
    • Hering, H.1    Sheng, M.2
  • 13
    • 0033529082 scopus 로고    scopus 로고
    • Dendritic spine changes associated with hippocampal long-term synaptic plasticity
    • Engert, F. & Bonhoeffer, T. Dendritic spine changes associated with hippocampal long-term synaptic plasticity. Nature 399, 66-70 (1999).
    • (1999) Nature , vol.399 , pp. 66-70
    • Engert, F.1    Bonhoeffer, T.2
  • 14
    • 0033583022 scopus 로고    scopus 로고
    • Rapid dendritic morphogenesis in CA1 hippocampal dendrites induced by synaptic activity
    • Maletic-Savatic, M., Malinow, R. & Svoboda, K. Rapid dendritic morphogenesis in CA1 hippocampal dendrites induced by synaptic activity. Science 283, 1923-1927 (1999).
    • (1999) Science , vol.283 , pp. 1923-1927
    • Maletic-Savatic, M.1    Malinow, R.2    Svoboda, K.3
  • 15
    • 0033604506 scopus 로고    scopus 로고
    • LTP promotes formation of multiple spine synapses between a single axon terminal and a dendrite
    • Toni, N., Buchs, P.A., Nikonenko, I., Bron, C.R. & Muller, D. LTP promotes formation of multiple spine synapses between a single axon terminal and a dendrite. Nature 402, 421-425 (1999).
    • (1999) Nature , vol.402 , pp. 421-425
    • Toni, N.1    Buchs, P.A.2    Nikonenko, I.3    Bron, C.R.4    Muller, D.5
  • 16
    • 0035708355 scopus 로고    scopus 로고
    • Dendritic spine geometry is critical for AMPA receptor expression in hippocampal CA1 pyramidal neurons
    • Matsuzaki, M. et al. Dendritic spine geometry is critical for AMPA receptor expression in hippocampal CA1 pyramidal neurons. Nat. Neurosci. 4, 1086-1092 (2001).
    • (2001) Nat. Neurosci. , vol.4 , pp. 1086-1092
    • Matsuzaki, M.1
  • 17
    • 0030239159 scopus 로고    scopus 로고
    • Increased density of multiple-head dendritic spines on medium-sized spiny neurons of the striatum in rats reared in a complex environment
    • Comery, T.A., Stamoudis, C.X., Irwin, S.A. & Greenough, W.T. Increased density of multiple-head dendritic spines on medium-sized spiny neurons of the striatum in rats reared in a complex environment. Neurobiol. Learn. Mem. 66, 93-96 (1996).
    • (1996) Neurobiol. Learn. Mem. , vol.66 , pp. 93-96
    • Comery, T.A.1    Stamoudis, C.X.2    Irwin, S.A.3    Greenough, W.T.4
  • 18
    • 0016251748 scopus 로고
    • Dendritic spine "dysgenesis" and mental retardation
    • Purpura, D.P. Dendritic spine "dysgenesis" and mental retardation. Science 186, 1126-1128 (1974).
    • (1974) Science , vol.186 , pp. 1126-1128
    • Purpura, D.P.1
  • 19
    • 0033797735 scopus 로고    scopus 로고
    • Dendritic anomalies in disorders associated with mental retardation
    • Kaufmann, W.E. & Moser, H.W. Dendritic anomalies in disorders associated with mental retardation. Cereb. Cortex 10, 981-991 (2000).
    • (2000) Cereb. Cortex , vol.10 , pp. 981-991
    • Kaufmann, W.E.1    Moser, H.W.2
  • 20
    • 0036082812 scopus 로고    scopus 로고
    • Dendritic spine pathology: Cause or consequence of neurological disorders?
    • Fiala, J.C., Spacek, J. & Harris, K.M. Dendritic spine pathology: cause or consequence of neurological disorders? Brain Res. Rev. 39, 29-54 (2002).
    • (2002) Brain Res. Rev. , vol.39 , pp. 29-54
    • Fiala, J.C.1    Spacek, J.2    Harris, K.M.3
  • 21
    • 0033152923 scopus 로고    scopus 로고
    • Structure, development, and plasticity of dendritic spines
    • Harris, K.M. Structure, development, and plasticity of dendritic spines. Curr. Opin. Neurobiol. 9, 343-348 (1999).
    • (1999) Curr. Opin. Neurobiol. , vol.9 , pp. 343-348
    • Harris, K.M.1
  • 22
    • 0030986183 scopus 로고    scopus 로고
    • Abnormal dendritic spines in fragile X knockout mice: Maturation and pruning deficits
    • Comery, T.A. et al. Abnormal dendritic spines in fragile X knockout mice: Maturation and pruning deficits. Proc. Natl. Acad. Sci. USA 94, 5401-5404 (1997).
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 5401-5404
    • Comery, T.A.1
  • 23
    • 0035879180 scopus 로고    scopus 로고
    • Abnormal development of dendritic spines in FMR1 knock-out mice
    • Nimchinsky, E.A., Oberlander, A.M. & Svoboda, K. Abnormal development of dendritic spines in FMR1 knock-out mice. J. Neurosci. 21, 5139-5146 (2001).
    • (2001) J. Neurosci. , vol.21 , pp. 5139-5146
    • Nimchinsky, E.A.1    Oberlander, A.M.2    Svoboda, K.3
  • 24
    • 0030656619 scopus 로고    scopus 로고
    • Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension
    • Uehata, M. et al. Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. Nature 389, 990-994 (1997).
    • (1997) Nature , vol.389 , pp. 990-994
    • Uehata, M.1
  • 25
    • 0034715885 scopus 로고    scopus 로고
    • Regulation and functions of Rho-associated kinase
    • Amano, M., Fukata, Y. & Kaibuchi, K. Regulation and functions of Rho-associated kinase. Exp. Cell Res. 261, 44-51 (2000).
    • (2000) Exp. Cell Res. , vol.261 , pp. 44-51
    • Amano, M.1    Fukata, Y.2    Kaibuchi, K.3
  • 26
    • 0033679292 scopus 로고    scopus 로고
    • Structure of the Homer EVH1 domain-peptide complex reveals a new twist in polyproline recognition
    • Beneken, J. et al. Structure of the Homer EVH1 domain-peptide complex reveals a new twist in polyproline recognition. Neuron 26, 143-154 (2000).
    • (2000) Neuron , vol.26 , pp. 143-154
    • Beneken, J.1
  • 27
    • 0038699101 scopus 로고    scopus 로고
    • Homer as both a scaffold and transduction molecule
    • Fagni, L., Worley, P.F. & Ango, F. Homer as both a scaffold and transduction molecule. Sci. STKE 137, 1-7 (2002).
    • (2002) Sci. STKE , vol.137 , pp. 1-7
    • Fagni, L.1    Worley, P.F.2    Ango, F.3
  • 28
    • 0342313718 scopus 로고    scopus 로고
    • Homer: A link between neural activity and glutamate receptor function
    • Xiao, B., Cheng, J. & Worley, P.F. Homer: a link between neural activity and glutamate receptor function. Curr. Opin. Neurobiol. 10, 370-374 (2000).
    • (2000) Curr. Opin. Neurobiol. , vol.10 , pp. 370-374
    • Xiao, B.1    Cheng, J.2    Worley, P.F.3
  • 29
    • 0037188502 scopus 로고    scopus 로고
    • Altered synaptic plasticity in a mouse model of fragile X mental retardation
    • Huber, K.M., Gallagher, S.M., Warren, S.T. & Bear, M.F. Altered synaptic plasticity in a mouse model of fragile X mental retardation. Proc. Natl. Acad. Sci. USA 99, 7746-7750 (2003).
    • (2003) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 7746-7750
    • Huber, K.M.1    Gallagher, S.M.2    Warren, S.T.3    Bear, M.F.4
  • 30
    • 0035913909 scopus 로고    scopus 로고
    • Regulating axon branch stability: The role of p190 RhoGAP in repressing a retraction signaling pathway
    • Billuart, P., Winter, C.G., Maresh, A., Zhao, X. & Luo L. Regulating axon branch stability: the role of p190 RhoGAP in repressing a retraction signaling pathway. Cell 107, 195-207 (2001).
    • (2001) Cell , vol.107 , pp. 195-207
    • Billuart, P.1    Winter, C.G.2    Maresh, A.3    Zhao, X.4    Luo, L.5
  • 31
    • 0034879863 scopus 로고    scopus 로고
    • Regulation of dendritic spine morphology and synaptic function by Shank and Homer
    • Sala, C. et al. Regulation of dendritic spine morphology and synaptic function by Shank and Homer. Neuron 31, 115-130 (2001).
    • (2001) Neuron , vol.31 , pp. 115-130
    • Sala, C.1
  • 32
    • 0038382054 scopus 로고    scopus 로고
    • Inhibition of dendritic spine morphogenesis and synaptic transmission by activity-inducible protein Homerla
    • Sala, C. et al. Inhibition of dendritic spine morphogenesis and synaptic transmission by activity-inducible protein Homerla. J. Neurosci. 23, 6327-6337 (2003).
    • (2003) J. Neurosci. , vol.23 , pp. 6327-6337
    • Sala, C.1
  • 33
    • 0033855708 scopus 로고    scopus 로고
    • Glutamate receptors regulate actin-based plasticity in dendritic spines
    • Fischer, M., Kaech, S., Wagner, U., Brinkhaus, H. & Matus, A. Glutamate receptors regulate actin-based plasticity in dendritic spines. Nat. Neurosci. 3, 887-894 (2000).
    • (2000) Nat. Neurosci. , vol.3 , pp. 887-894
    • Fischer, M.1    Kaech, S.2    Wagner, U.3    Brinkhaus, H.4    Matus, A.5
  • 34
    • 0036176244 scopus 로고    scopus 로고
    • Rapid turnover of actin in dendritic spines and its regulation by activity
    • Star, E.N., Kwiatkowski, D.J. & Murthy, V.N. Rapid turnover of actin in dendritic spines and its regulation by activity. Nat. Neurosci. 5, 239-246 (2002).
    • (2002) Nat. Neurosci. , vol.5 , pp. 239-246
    • Star, E.N.1    Kwiatkowski, D.J.2    Murthy, V.N.3
  • 35
    • 0242384720 scopus 로고    scopus 로고
    • Activity-induced targeting of profilin and stabilization of dendritic spine morphology
    • Ackermann, M. & Matus, A. Activity-induced targeting of profilin and stabilization of dendritic spine morphology. Nat. Neurosci. 6, 1194-1200 (2003).
    • (2003) Nat. Neurosci. , vol.6 , pp. 1194-1200
    • Ackermann, M.1    Matus, A.2
  • 36
    • 0033366383 scopus 로고    scopus 로고
    • Miniature synaptic events maintain dendritic spines via AMPA receptor activation
    • McKinney, R.A., Capogna, M., Dürr, R., Gähwiler, B.H. & Thompson, S.M. Miniature synaptic events maintain dendritic spines via AMPA receptor activation. Nat. Neurosci. 2, 44-49 (1999).
    • (1999) Nat. Neurosci. , vol.2 , pp. 44-49
    • McKinney, R.A.1    Capogna, M.2    Dürr, R.3    Gähwiler, B.H.4    Thompson, S.M.5
  • 37
    • 0037015579 scopus 로고    scopus 로고
    • Dendrite growth increased by visual activity requires NMDA receptor and Rho GTPases
    • Sin, W.C., Haas, K., Ruthazer, E.S. & Cline, H.T. Dendrite growth increased by visual activity requires NMDA receptor and Rho GTPases. Nature 419, 475-480 (2002).
    • (2002) Nature , vol.419 , pp. 475-480
    • Sin, W.C.1    Haas, K.2    Ruthazer, E.S.3    Cline, H.T.4
  • 38
    • 10744221298 scopus 로고    scopus 로고
    • Homer binds TRPC family channels and is required for gating of TRPC1 by IP3 receptors
    • Yuan, J.P. et al. Homer binds TRPC family channels and is required for gating of TRPC1 by IP3 receptors. Cell 114, 777-789 (2003).
    • (2003) Cell , vol.114 , pp. 777-789
    • Yuan, J.P.1
  • 39
    • 0032742098 scopus 로고    scopus 로고
    • Release of calcium from stores alters the morphology of dendritic spines in cultured hippocampal neurons
    • Korkotian E. & Segal, M. Release of calcium from stores alters the morphology of dendritic spines in cultured hippocampal neurons. Proc. Natl. Acad. Sci. USA 96, 12068-12072 (1999).
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 12068-12072
    • Korkotian, E.1    Segal, M.2
  • 40
    • 0029825623 scopus 로고    scopus 로고
    • Modulatory role of Drebrin on the cytoskeleton within dendritic spines in the rat cerebral cortex
    • Hayashi, K. et al. Modulatory role of Drebrin on the cytoskeleton within dendritic spines in the rat cerebral cortex. J. Neurosci. 16, 7161-7170 (1996).
    • (1996) J. Neurosci. , vol.16 , pp. 7161-7170
    • Hayashi, K.1
  • 41
    • 0034668918 scopus 로고    scopus 로고
    • Regulation of spine calcium dynamics by rapid spine motility
    • Majewska, A., Tashiro, A. & Yuste, R. Regulation of spine calcium dynamics by rapid spine motility. J. Neurosci. 20, 8262-8268 (2000).
    • (2000) J. Neurosci. , vol.20 , pp. 8262-8268
    • Majewska, A.1    Tashiro, A.2    Yuste, R.3
  • 42
    • 0033947688 scopus 로고    scopus 로고
    • From form to function: Calcium compartmentalization in dendritic spines
    • Yuste, R., Majewska, A. & Holthoff, K. From form to function: calcium compartmentalization in dendritic spines. Nat. Neurosci. 3, 653-659 (2000).
    • (2000) Nat. Neurosci. , vol.3 , pp. 653-659
    • Yuste, R.1    Majewska, A.2    Holthoff, K.3
  • 43
    • 0038495879 scopus 로고    scopus 로고
    • Oligophrenin-1 (OPHN1) gene mutation causes X-linked mental retardation with epilepsy, rostral ventricular enlargement and cerebellar hypoplasia
    • Bergmann, C. et al. Oligophrenin-1 (OPHN1) gene mutation causes X-linked mental retardation with epilepsy, rostral ventricular enlargement and cerebellar hypoplasia. Brain 126, 1537-1544 (2003).
    • (2003) Brain , vol.126 , pp. 1537-1544
    • Bergmann, C.1
  • 44
    • 0037531657 scopus 로고    scopus 로고
    • Mutations in the oligophrenin-1 gene (OPHN1) cause X linked congenital cerebellar hypoplasia
    • Philip, N. et al. Mutations in the oligophrenin-1 gene (OPHN1) cause X linked congenital cerebellar hypoplasia. J. Med. Genet. 40, 441-446 (2003).
    • (2003) J. Med. Genet. , vol.40 , pp. 441-446
    • Philip, N.1
  • 45
    • 0029802561 scopus 로고    scopus 로고
    • RAC regulation of actin polymerization and proliferation by a pathway distinct from Jun kinase
    • Joneson, T., McDonough, M., Bar-Sagi, D. & Van Aelst, L. RAC regulation of actin polymerization and proliferation by a pathway distinct from Jun kinase. Science 274, 1374-1376 (1996).
    • (1996) Science , vol.274 , pp. 1374-1376
    • Joneson, T.1    McDonough, M.2    Bar-Sagi, D.3    Van Aelst, L.4
  • 46
    • 0035797521 scopus 로고    scopus 로고
    • Regulation of dendritic spine morphology by SPAR, a PSD-95-associated RapGAP
    • Pak, D.T., Yang, S., Rudolph-Correia, S., Kim, E. & Sheng, M. Regulation of dendritic spine morphology by SPAR, a PSD-95-associated RapGAP. Neuron 31, 289-303 (2001).
    • (2001) Neuron , vol.31 , pp. 289-303
    • Pak, D.T.1    Yang, S.2    Rudolph-Correia, S.3    Kim, E.4    Sheng, M.5
  • 47
    • 0025805120 scopus 로고
    • A simple method for organotypic cultures of nervous tissue
    • Stoppini, L., Buchs, P.A. & Muller, D. A simple method for organotypic cultures of nervous tissue. J. Neurosci. Methods 37, 173-182 (1991).
    • (1991) J. Neurosci. Methods , vol.37 , pp. 173-182
    • Stoppini, L.1    Buchs, P.A.2    Muller, D.3
  • 48
    • 0035374569 scopus 로고    scopus 로고
    • RhoA inhibits the nerve growth factor-induced Rac1 activation through Rho-associated kinase-dependent pathway
    • Yamaguchi, Y., Katoh, H., Yasui, H., Mori, K. & Negishi, M. RhoA inhibits the nerve growth factor-induced Rac1 activation through Rho-associated kinase-dependent pathway. J. Biol. Chem. 276, 18977-18983 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 18977-18983
    • Yamaguchi, Y.1    Katoh, H.2    Yasui, H.3    Mori, K.4    Negishi, M.5
  • 49
    • 0029788216 scopus 로고    scopus 로고
    • Interaction of the N-methyl-D-aspartate receptor complex with a novel synapse-associated protein, SAP102
    • Lau, L.F. et al. Interaction of the N-methyl-D-aspartate receptor complex with a novel synapse-associated protein, SAP102. J. Biol. Chem. 271, 21622-21628 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 21622-21628
    • Lau, L.F.1
  • 50
    • 0026492629 scopus 로고
    • The rat brain postsynaptic density fraction contains a homolog of the Drosophila discs-large tumor suppressor protein
    • Cho, K.O., Hunt, C.A. & Kennedy, M.B. The rat brain postsynaptic density fraction contains a homolog of the Drosophila discs-large tumor suppressor protein. Neuron 9, 929-942 (1992).
    • (1992) Neuron , vol.9 , pp. 929-942
    • Cho, K.O.1    Hunt, C.A.2    Kennedy, M.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.