Polycomb repressive complex 2-dependent and -Independent functions of Jarid2 in transcriptional regulation in Drosophila

Molecular and Cellular Biology

Volumn 32, Issue 9, 2012, Pages 1683-1693

  Herz, Hans Martin ^a   Mohan, Man ^a   Garrett, Alexander S ^a   Miller, Caitlynn ^a   Casto, David ^a   Zhang, Ying ^a   Seidel, Christopher ^a   Haug, Jeffrey S ^a   Florens, Laurence ^a   Washburn, Michael P ^a,b   Yamaguchi, Masamitsu ^c   Shiekhattar, Ramin ^d   Shilatifard, Ali ^a  

^a STOWERS INSTITUTE FOR MEDICAL RESEARCH   (United States)

^b UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^c KYOTO INSTITUTE OF TECHNOLOGY   (Japan)

^d WISTAR INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DROSOPHILA PROTEIN; ENHANCER OF ZESTE; HISTONE H3; HOMEODOMAIN PROTEIN; JARID2 PROTEIN; POLYCOMB GROUP PROTEIN; POLYCOMB REPRESSIVE COMPLEX 2 PROTEIN; REGULATOR PROTEIN; SUPPRESSOR OF ZESTE 12; UNCLASSIFIED DRUG;

ARTICLE; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DROSOPHILA; EMBRYO; FLY; GENE EXPRESSION PROFILING; GENE SEQUENCE; HISTONE METHYLATION; HISTONE MODIFICATION; HOMEOBOX; IN VIVO STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TRANSCRIPTION TERMINATION;

ANIMALS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION; HISTONE-LYSINE N-METHYLTRANSFERASE; METHYLATION; PROTEIN BINDING; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

MAMMALIA;

EID: 84861365971     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.06503-11     Document Type: Article

References (53)

1. Beisel C, Paro R. 2011. Silencing chromatin: comparing modes and mechanisms. Nat. Rev. Genet. 12:123-135.
2. Boyer LA, et al. 2006. Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature 441:349-353.
3. Cao R, Zhang Y. 2004. SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex. Mol. Cell 15:57-67.
4. Carrington EA, Jones RS. 1996. The Drosophila Enhancer of zeste gene encodes a chromosomal protein: examination of wild-type and mutant protein distribution. Development 122:4073-4083.
5. Corona DF, et al. 2007. ISWI regulates higher-order chromatin structure and histone H1 assembly in vivo. PLoS Biol. 5:e232.
6. Culi J, Aroca P, Modolell J, Mann RS. 2006. jing is required for wing development and to establish the proximo-distal axis of the leg in Drosophila melanogaster. Genetics 173:255-266.
7. Curtis BJ, Zraly CB, Marenda DR, Dingwall AK. 2011. Histone lysine demethylases function as co-repressors of SWI/SNF remodeling activities during Drosophila wing development. Dev. Biol. 350:534-547.
8. Enderle D, et al. 2011. Polycomb preferentially targets stalled promoters of coding and noncoding transcripts. Genome Res. 21:216-226.
9. Fischle W, et al. 2003. Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains. Genes Dev. 17:1870-1881.
10. Gautier L, Cope L, Bolstad BM, Irizarry RA. 2004. affy-analysis of Affymetrix GeneChip data at the probe level. Bioinformatics 20:307-315.
11. Gaytan de Ayala Alonso A, et al. 2007. A genetic screen identifies novel polycomb group genes in Drosophila. Genetics 176:2099-2108.
12. Herz HM, Shilatifard A. 2010. The JARID2-PRC2 duality. Genes Dev. 24:857-861.
13. Jacob E, Hod-Dvorai R, Ben-Mordechai OL, Boyko Y, Avni O. 2011. Dual function of polycomb group proteins in differentiated murine T helper (CD4+) cells. J. Mol. Signal. 6:5.
14. Jung J, Mysliwiec MR, Lee Y. 2005. Roles of JUMONJI in mouse embryonic development. Dev. Dyn. 232:21-32.
15. Kent WJ, et al. 2002. The human genome browser at UCSC. Genome Res. 12:996-1006.
16. Klose RJ, Kallin EM, Zhang Y. 2006. JmjC-domain-containing proteins and histone demethylation. Nat. Rev. Genet. 7:715-727.
17. Klymenko T, Müller J. 2004. The histone methyltransferases Trithorax and Ash1 prevent transcriptional silencing by Polycomb group proteins. EMBO Rep. 5:373-377.
18. Landeira D, Fisher AG. 2011. Inactive yet indispensable: the tale of Jarid2. Trends Cell Biol. 21:74-80.
19. Landeira D, et al. 2010. Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators. Nat. Cell Biol. 12: 618-624.
20. Langmead B, Trapnell C, Pop M, Salzberg SL. 2009. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol. 10:R25. http://genomebiology.com/2009/10/3/R25.
21. Lee TI, et al. 2006. Control of developmental regulators by Polycomb in human embryonic stem cells. Cell 125:301-313.
22. Li G, et al. 2010. Jarid2 and PRC2, partners in regulating gene expression. Genes Dev. 24:368-380.
23. Liu Y, Montell DJ. 2001. Jing: a downstream target of slbo required for developmental control of border cell migration. Development 128:321-330.
24. Margueron R, et al. 2009. Role of the polycomb protein EED in the propagation of repressive histone marks. Nature 461:762-767.
25. Mills AA. 2010. Throwing the cancer switch: reciprocal roles of polycomb and trithorax proteins. Nat. Rev. Cancer 10:669-682.
26. Min J, Zhang Y, Xu RM. 2003. Structural basis for specific binding of Polycomb chromodomain to histone H3 methylated at Lys 27. Genes Dev. 17:1823-1828.
27. Mohan M, et al. 2007. The Drosophila insulator proteins CTCF and CP190 link enhancer blocking to body patterning. EMBO J. 26:4203-4214.
28. Mousavi K, Zare H, Wang AH, Sartorelli V. 2012. Polycomb protein Ezh1 promotes RNA polymerase II elongation. Mol. Cell 45:255-262.
29. Ohno K, McCabe D, Czermin B, Imhof A, Pirrotta V. 2008. ESC, ESCL and their roles in polycomb group mechanisms. Mech. Dev. 125:527-541.
30. Papp B, Müller J. 2006. Histone trimethylation and the maintenance of transcriptional ON and OFF states by trxG and PcG proteins. Genes Dev. 20:2041-2054.
31. Pasini D, Bracken AP, Hansen JB, Capillo M, Helin K. 2007. The polycomb group protein Suz12 is required for embryonic stem cell differentiation. Mol. Cell. Biol. 27:3769-3779.
32. Pasini D, et al. 2010. JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells. Nature 464:306-310.
33. Peng JC, et al. 2009. Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells. Cell 139: 1290-1302.
34. Poux S, Horard B, Sigrist CJ, Pirrotta V. 2002. The Drosophila trithorax protein is a coactivator required to prevent re-establishment of polycomb silencing. Development 129:2483-2493.
35. Richly H, et al. 2010. Transcriptional activation of polycomb-repressed genes by ZRF1. Nature 468:1124-1128.
36. Ringrose L, Rehmsmeier M, Dura JM, Paro R. 2003. Genome-wide prediction of Polycomb/Trithorax response elements in Drosophila melanogaster. Dev. Cell 5:759-771.
37. Sasai N, Kato Y, Kimura G, Takeuchi T, Yamaguchi M. 2007. The Drosophila jumonji gene encodes a JmjC-containing nuclear protein that is required for metamorphosis. FEBS J. 274:6139-6151.
38. Sawarkar R, Paro R. 2010. Interpretation of developmental signaling at chromatin: the Polycomb perspective. Dev. Cell 19:651-661.
39. Scheuermann JC, et al. 2010. Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB. Nature 465:243-247.
40. Schuettengruber B, Chourrout D, Vervoort M, Leblanc B, Cavalli G. 2007. Genome regulation by polycomb and trithorax proteins. Cell 128: 735-745.
41. Schwartz YB, Pirrotta V. 2007. Polycomb silencing mechanisms and the management of genomic programmes. Nat. Rev. Genet. 8:9-22.
42. Shen X, et al. 2009. Jumonji modulates polycomb activity and selfrenewal versus differentiation of stem cells. Cell 139:1303-1314.
43. Simon J, Chiang A, Bender W, Shimell MJ, O'Connor M. 1993. Elements of the Drosophila bithorax complex that mediate repression by Polycomb group products. Dev. Biol. 158:131-144.
44. Simon JA, Kingston RE. 2009. Mechanisms of polycomb gene silencing: knowns and unknowns. Nat. Rev. Mol. Cell. Biol. 10:697-708.
45. Sing A, et al. 2009. A vertebrate Polycomb response element governs segmentation of the posterior hindbrain. Cell 138:885-897.
46. Smyth GK, Michaud J, Scott HS. 2005. Use of within-array replicate spots for assessing differential expression in microarray experiments. Bioinformatics 21:2067-2075.
47. Srinivasan S, Dorighi KM, Tamkun JW. 2008. Drosophila Kismet regulates histone H3 lysine 27 methylation and early elongation by RNA polymerase II. PLoS Genet. 4:e1000217.
48. Warming S. 2005. BAC recombineering using the modified DH10B strain SW102 and a galK positive/counterselection cassette. NCI-Frederick, Frederick, MD. http://web.ncifcrf.gov/research/brb/protocol/Protocol3 _SW102_galK_v2.pdf.
49. Woo CJ, Kharchenko PV, Daheron L, Park PJ, Kingston RE. 2010. A region of the humanHOXDcluster that confers polycomb-group responsiveness. Cell 140:99-110.
50. Wu M, et al. 2008. Molecular regulation of H3K4 trimethylation by Wdr82, a component of human Set1/COMPASS. Mol. Cell. Biol. 28: 7337-7344.
51. Young MD, et al. 2011. ChIP-seq analysis reveals distinct H3K27me3 profiles that correlate with transcriptional activity. Nucleic Acids Res. 39: 7415-7427.
52. Zhang Y, et al. 2008. Model-based analysis of ChIP-Seq (MACS). Genome Biol. 9:R137. http://genomebiology.com/content/9/9/R137.
53. Zhang Z, et al. 2011. PRC2 complexes with JARID2, MTF2, and esPRC2p48 in ES cells to modulate ES cell pluripotency and somatic cell reprogramming. Stem Cells 29:229-240.