Low levels of human HIP14 are sufficient to rescue neuropathological, behavioural, and enzymatic defects due to loss of murine HIP14 in Hip14-/- mice

PLoS ONE

Volumn 7, Issue 5, 2012, Pages

  Young, Fiona B ^a   Franciosi, Sonia ^a   Spreeuw, Amanda ^a   Deng, Yu ^a   Sanders, Shaun ^a   Tam, Natalie C M ^a   Huang, Kun ^a   Singaraja, Roshni R ^a   Zhang, Weining ^a   Bissada, Nagat ^a   Kay, Chris ^a   Hayden, Michael R ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; ENKEPHALIN; HUNTINGTIN INTERACTING PROTEIN 14; MESSENGER RNA; PHOSPHOPROTEIN DARPP 32; UNCLASSIFIED DRUG; HIP14 PROTEIN, MOUSE; NERVE PROTEIN; PRIMER DNA; SIGNAL TRANSDUCING ADAPTOR PROTEIN; ZDHHC17 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; BEHAVIOR DISORDER; CONTROLLED STUDY; COORDINATION DISORDER; EMBRYO; FEMALE; GENE; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE LOSS; HIP14 GENE; HUMAN; HUNTINGTON CHOREA; IN VIVO STUDY; MALE; MOUSE; NEUROLOGIC DISEASE; NEUROPATHOLOGY; NONHUMAN; PALMITOYLATION; PROTEIN DEFECT; PROTEIN EXPRESSION; PROTEIN FUNCTION; WEIGHT REDUCTION; WESTERN BLOTTING; ANALYSIS OF VARIANCE; ANIMAL; BODY WEIGHT; CROSS BREEDING; DRUG EFFECT; GENETICS; IMMUNOHISTOCHEMISTRY; LIPOYLATION; LOCOMOTION; METABOLISM; MOUSE MUTANT; POLYMERASE CHAIN REACTION; REAL TIME POLYMERASE CHAIN REACTION; ROTAROD TEST; TRANSGENIC MOUSE;

MURINAE; MUS; MUS MUSCULUS;

ACYLTRANSFERASES; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANALYSIS OF VARIANCE; ANIMALS; BLOTTING, WESTERN; BODY WEIGHT; CHROMOSOMES, ARTIFICIAL, BACTERIAL; CROSSES, GENETIC; DNA PRIMERS; HUMANS; IMMUNOHISTOCHEMISTRY; LIPOYLATION; LOCOMOTION; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; NERVE TISSUE PROTEINS; POLYMERASE CHAIN REACTION; REAL-TIME POLYMERASE CHAIN REACTION; ROTAROD PERFORMANCE TEST;

EID: 84861358216     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0036315     Document Type: Article

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