메뉴 건너뛰기




Volumn 2, Issue 5, 2000, Pages 1-11

Searching the unknown with gene trapping

Author keywords

development; developmental biology; embryonal stem cell; ES cell; expression marker; gene knockouts; genomics; lacZ; mutation

Indexed keywords


EID: 85012543064     PISSN: 14623994     EISSN: 14623994     Source Type: Journal    
DOI: 10.1017/S1462399400001824     Document Type: Article
Times cited : (6)

References (38)
  • 1
    • 10244230901 scopus 로고    scopus 로고
    • A gene map of the human genome
    • PubMed ID: 97002443
    • Schuler, G.D. et al. (1996) A gene map of the human genome. Science 274, 540–546, PubMed ID: 97002443
    • (1996) Science , vol.274 , pp. 540-546
    • Schuler, G.D.1
  • 2
    • 0019133661 scopus 로고
    • Mutations affecting segment number and polarity in Drosophila
    • PubMed ID: 81052383
    • Nusslein-Volhard, C. and Wieschaus, E. (1980) Mutations affecting segment number and polarity in Drosophila. Nature 287, 795–801, PubMed ID: 81052383
    • (1980) Nature , vol.287 , pp. 795-801
    • Nusslein-Volhard, C.1    Wieschaus, E.2
  • 3
    • 0016063911 scopus 로고
    • The genetics of Caenorhabditis elegans
    • PubMed ID: 74271161
    • Brenner, S. (1974) The genetics of Caenorhabditis elegans. Genetics 77, 71–94, PubMed ID: 74271161
    • (1974) Genetics , vol.77 , pp. 71-94
    • Brenner, S.1
  • 4
    • 0025837661 scopus 로고
    • Mutations affecting body organization in the Arabidopsis embryo
    • Mayer, U. et al. (1991) Mutations affecting body organization in the Arabidopsis embryo. Nature 353, 402–407
    • (1991) Nature , vol.353 , pp. 402-407
    • Mayer, U.1
  • 5
    • 0031871487 scopus 로고    scopus 로고
    • Mouse models of genetic disease: new approaches, new paradigms
    • PubMed ID: 98397579
    • Brown, S.D. (1998) Mouse models of genetic disease: new approaches, new paradigms. J Inherit Metab Dis 21, 532–539, PubMed ID: 98397579
    • (1998) J Inherit Metab Dis , vol.21 , pp. 532-539
    • Brown, S.D.1
  • 6
    • 0019826665 scopus 로고
    • Establishment in culture of pluripotential cells from mouse embryos
    • PubMed ID: 81220990
    • Evans, M.J. and Kaufman, M.H. (1981) Establishment in culture of pluripotential cells from mouse embryos. Nature 292, 154–156, PubMed ID: 81220990
    • (1981) Nature , vol.292 , pp. 154-156
    • Evans, M.J.1    Kaufman, M.H.2
  • 7
    • 0023646810 scopus 로고
    • Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells
    • PubMed ID: 88027032
    • Thomas, K.R. and Capecchi, M.R. (1987) Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell 51, 503–512, PubMed ID: 88027032
    • (1987) Cell , vol.51 , pp. 503-512
    • Thomas, K.R.1    Capecchi, M.R.2
  • 8
    • 0030964025 scopus 로고    scopus 로고
    • Gene trapping and functional genomics
    • PubMed ID: 97433599
    • Evans, M.J., Carlton, M.B. and Russ, A.P. (1997) Gene trapping and functional genomics. Trends Genet 13, 370–374, PubMed ID: 97433599
    • (1997) Trends Genet , vol.13 , pp. 370-374
    • Evans, M.J.1    Carlton, M.B.2    Russ, A.P.3
  • 9
    • 0024212067 scopus 로고
    • Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer
    • PubMed ID: 89057866
    • Frohman, M.A., Dush, M.K. and Martin, G.R. (1988) Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer. Proc Natl Acad Sci U S A 85, 8998–9002, PubMed ID: 89057866
    • (1988) Proc Natl Acad Sci U S A , vol.85 , pp. 8998-9002
    • Frohman, M.A.1    Dush, M.K.2    Martin, G.R.3
  • 10
    • 0026693090 scopus 로고
    • A gene trap approach in mouse embryonic stem cells: the lacZ reported is activated by splicing, reflects endogenous gene expression, and is mutagenic in mice
    • PubMed ID: 92275355
    • Skarnes, W.C., Auerbach, B.A. and Joyner, A.L. (1992) A gene trap approach in mouse embryonic stem cells: the lacZ reported is activated by splicing, reflects endogenous gene expression, and is mutagenic in mice. Genes Dev 6, 903–918, PubMed ID: 92275355
    • (1992) Genes Dev , vol.6 , pp. 903-918
    • Skarnes, W.C.1    Auerbach, B.A.2    Joyner, A.L.3
  • 11
    • 0032499252 scopus 로고    scopus 로고
    • Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells
    • PubMed ID: 98219085
    • Zambrowicz, B.P. et al. (1998) Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells. Nature 392, 608–611, PubMed ID: 98219085
    • (1998) Nature , vol.392 , pp. 608-611
    • Zambrowicz, B.P.1
  • 12
    • 0029023713 scopus 로고
    • Capturing genes encoding membrane and secreted proteins important for mouse development
    • PubMed ID: 95327693
    • Skarnes, W.C. et al. (1995) Capturing genes encoding membrane and secreted proteins important for mouse development. Proc Natl Acad Sci U S A 92, 6592–6596, PubMed ID: 95327693
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 6592-6596
    • Skarnes, W.C.1
  • 13
    • 0029926149 scopus 로고    scopus 로고
    • An induction gene trap screen in embryonic stem cells: Identification of genes that respond to retinoic acid in vitro
    • PubMed ID: 96202336
    • Forrester, L.M. et al. (1996) An induction gene trap screen in embryonic stem cells: Identification of genes that respond to retinoic acid in vitro. Proc Natl Acad Sci U S A 93, 1677–1682, PubMed ID: 96202336
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 1677-1682
    • Forrester, L.M.1
  • 14
    • 0031801688 scopus 로고    scopus 로고
    • Efficient poly A trap approach allows the capture of genes specifically active in differentiated embryonic stem cells and in mouse embryos
    • PubMed ID: 98289809
    • Salminen, M., Meyer, B.I. and Gruss, P. (1998) Efficient poly A trap approach allows the capture of genes specifically active in differentiated embryonic stem cells and in mouse embryos. Dev Dyn 212, 326–333, PubMed ID: 98289809
    • (1998) Dev Dyn , vol.212 , pp. 326-333
    • Salminen, M.1    Meyer, B.I.2    Gruss, P.3
  • 15
    • 0031781469 scopus 로고    scopus 로고
    • Gene trap expression and mutational analysis for genes involved in the development of the mammalian nervous system
    • PubMed ID: 98289797
    • Stoykova, A. et al. (1998) Gene trap expression and mutational analysis for genes involved in the development of the mammalian nervous system. Dev Dyn 212, 198–213, PubMed ID: 98289797
    • (1998) Dev Dyn , vol.212 , pp. 198-213
    • Stoykova, A.1
  • 16
    • 0024723364 scopus 로고
    • P-element-mediated enhancer detection: a versatile method to study development in Drosophila
    • PubMed ID: 90108679
    • Bellen, H.J. et al. (1989) P-element-mediated enhancer detection: a versatile method to study development in Drosophila. Genes Dev 3, 1288–1300, PubMed ID: 90108679
    • (1989) Genes Dev , vol.3 , pp. 1288-1300
    • Bellen, H.J.1
  • 17
    • 0007253213 scopus 로고
    • Analysis of mammalian cell genetic regulation in situ by using retrovirus-derived “portable exons” carrying the Escherichia coli lacZ gene
    • PubMed ID: 89315828
    • Brenner, D.G., Lin-Chao, S. and Cohen, S.N. (1989) Analysis of mammalian cell genetic regulation in situ by using retrovirus-derived “portable exons” carrying the Escherichia coli lacZ gene. Proc Natl Acad Sci U S A 86, 5517–5521, PubMed ID: 89315828
    • (1989) Proc Natl Acad Sci U S A , vol.86 , pp. 5517-5521
    • Brenner, D.G.1    Lin-Chao, S.2    Cohen, S.N.3
  • 18
    • 0026635754 scopus 로고
    • Selective disruption of genes expressed in totipotent embryonal stem cells
    • PubMed ID: 92275356
    • von Melchner, H. et al. (1992) Selective disruption of genes expressed in totipotent embryonal stem cells. Genes Dev 6, 919–927, PubMed ID: 92275356
    • (1992) Genes Dev , vol.6 , pp. 919-927
    • von Melchner, H.1
  • 19
    • 0028894298 scopus 로고
    • A large-scale gene-trap screen for insertional mutations in developmentally regulated genes in mice
    • PubMed ID: 95229068
    • Wurst, W. et al. (1995) A large-scale gene-trap screen for insertional mutations in developmentally regulated genes in mice. Genetics 139, 889–899, PubMed ID: 95229068
    • (1995) Genetics , vol.139 , pp. 889-899
    • Wurst, W.1
  • 20
    • 0031746343 scopus 로고    scopus 로고
    • Large-scale screening for developmental genes in embryonic stem cells and embryoid bodies using retroviral entrapment vectors
    • PubMed ID: 98289796
    • Xiong, J.W. et al. (1998) Large-scale screening for developmental genes in embryonic stem cells and embryoid bodies using retroviral entrapment vectors. Dev Dyn 212, 181–197, PubMed ID: 98289796
    • (1998) Dev Dyn , vol.212 , pp. 181-197
    • Xiong, J.W.1
  • 21
    • 0031779540 scopus 로고    scopus 로고
    • The mouse Gtl2 gene is differentially expressed during embryonic development, encodes multiple alternatively spliced transcripts, and may act as an RNA
    • PubMed ID: 98289798
    • Schuster-Gossler, K. et al. (1998) The mouse Gtl2 gene is differentially expressed during embryonic development, encodes multiple alternatively spliced transcripts, and may act as an RNA. Dev Dyn 212, 214–228, PubMed ID: 98289798
    • (1998) Dev Dyn , vol.212 , pp. 214-228
    • Schuster-Gossler, K.1
  • 22
    • 0025992469 scopus 로고
    • Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice
    • PubMed ID: 91357468
    • Friedrich, G. and Soriano, P. (1991) Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice. Genes Dev 5, 1513–1523, PubMed ID: 91357468
    • (1991) Genes Dev , vol.5 , pp. 1513-1523
    • Friedrich, G.1    Soriano, P.2
  • 23
    • 0030879143 scopus 로고    scopus 로고
    • Evidence for the stochastic integration of gene trap vectors into the mouse germline
    • PubMed ID: 97248607
    • Chowdhury, K. et al. (1997) Evidence for the stochastic integration of gene trap vectors into the mouse germline. Nucleic Acids Res 25, 1531–1536, PubMed ID: 97248607
    • (1997) Nucleic Acids Res , vol.25 , pp. 1531-1536
    • Chowdhury, K.1
  • 24
    • 0029328337 scopus 로고
    • A new strategy of gene trapping in ES cells using 3'RACE
    • PubMed ID: 95384208
    • Yoshida, M. et al. (1995) A new strategy of gene trapping in ES cells using 3'RACE. Transgenic Res 4, 277–287, PubMed ID: 95384208
    • (1995) Transgenic Res , vol.4 , pp. 277-287
    • Yoshida, M.1
  • 25
    • 0030879562 scopus 로고    scopus 로고
    • Functional genomics in mice by tagged sequence mutagenesis
    • PubMed ID: 97385236
    • Hicks, G.G. et al. (1997) Functional genomics in mice by tagged sequence mutagenesis. Nat Genet 16, 338–344, PubMed ID: 97385236
    • (1997) Nat Genet , vol.16 , pp. 338-344
    • Hicks, G.G.1
  • 26
    • 0031747715 scopus 로고    scopus 로고
    • Efficiency assessment of the gene trap approach
    • PubMed ID: 98289795
    • Voss, A.K., Thomas, T. and Gruss, P. (1998) Efficiency assessment of the gene trap approach. Dev Dyn 212, 171–180, PubMed ID: 98289795
    • (1998) Dev Dyn , vol.212 , pp. 171-180
    • Voss, A.K.1    Thomas, T.2    Gruss, P.3
  • 27
    • 0030947962 scopus 로고    scopus 로고
    • Rapid sequence analysis of gene trap integrations to generate a resource of insertional mutations in mice
    • PubMed ID: 97228906
    • Townley, D.J. et al. (1997) Rapid sequence analysis of gene trap integrations to generate a resource of insertional mutations in mice. Genome Res 7, 293–298, PubMed ID: 97228906
    • (1997) Genome Res , vol.7 , pp. 293-298
    • Townley, D.J.1
  • 28
    • 0031748836 scopus 로고    scopus 로고
    • Compensation for a gene trap mutation in the murine microtubule- associated protein 4 locus by alternative polyadenylation and alternative splicing
    • PubMed ID: 98289802
    • Voss, A.K., Thomas, T. and Gruss, P. (1998) Compensation for a gene trap mutation in the murine microtubule- associated protein 4 locus by alternative polyadenylation and alternative splicing. Dev Dyn 212, 258–266, PubMed ID: 98289802
    • (1998) Dev Dyn , vol.212 , pp. 258-266
    • Voss, A.K.1    Thomas, T.2    Gruss, P.3
  • 29
    • 0030980110 scopus 로고    scopus 로고
    • An evolutionarily conserved region in the second intron of the human nestin gene directs gene expression to CNS progenitor cells and to early neural crest cells
    • PubMed ID: 97258113
    • Lothian, C. and Lendahl, U. (1997) An evolutionarily conserved region in the second intron of the human nestin gene directs gene expression to CNS progenitor cells and to early neural crest cells. Eur J Neurosci 9, 452–462, PubMed ID: 97258113
    • (1997) Eur J Neurosci , vol.9 , pp. 452-462
    • Lothian, C.1    Lendahl, U.2
  • 30
    • 0031170789 scopus 로고    scopus 로고
    • A conserved cluster of homeodomain binding sites in the mouse Hoxa-4 intron functions in Drosophila embryos as an enhancer that is directly regulated by Ultrabithorax
    • PubMed ID: 97332514
    • Haerry, T.E. and Gehring, W.J. (1997) A conserved cluster of homeodomain binding sites in the mouse Hoxa-4 intron functions in Drosophila embryos as an enhancer that is directly regulated by Ultrabithorax. Dev Biol 186, 1–15, PubMed ID: 97332514
    • (1997) Dev Biol , vol.186 , pp. 1-15
    • Haerry, T.E.1    Gehring, W.J.2
  • 31
    • 0029798732 scopus 로고    scopus 로고
    • A limited temporal window for the derivation of multilineage repopulating hematopoietic progenitors during embryonal stem cell differentiation in vitro
    • PubMed ID: 96329559
    • Hole, N. et al. (1996) A limited temporal window for the derivation of multilineage repopulating hematopoietic progenitors during embryonal stem cell differentiation in vitro. Blood 88, 1266–1276, PubMed ID: 96329559
    • (1996) Blood , vol.88 , pp. 1266-1276
    • Hole, N.1
  • 32
    • 0030926713 scopus 로고    scopus 로고
    • In vitro preselection of gene-trapped embryonic stem cell clones for characterizing novel developmentally regulated genes in the mouse
    • PubMed ID: 97330624
    • Baker, R.K. et al. (1997) In vitro preselection of gene-trapped embryonic stem cell clones for characterizing novel developmentally regulated genes in the mouse. Dev Biol 185, 201–214, PubMed ID: 97330624
    • (1997) Dev Biol , vol.185 , pp. 201-214
    • Baker, R.K.1
  • 33
    • 0032535384 scopus 로고    scopus 로고
    • Expression trapping: identification of novel genes expressed in hematopoietic and endothelial lineages by gene trapping in ES cells
    • PubMed ID: 99061779
    • Stanford, W.L. et al. (1998) Expression trapping: identification of novel genes expressed in hematopoietic and endothelial lineages by gene trapping in ES cells. Blood 92, 4622–4631, PubMed ID: 99061779
    • (1998) Blood , vol.92 , pp. 4622-4631
    • Stanford, W.L.1
  • 34
    • 0033991659 scopus 로고    scopus 로고
    • Gene trapping of two novel genes, Hzf and Hhl, expressed in hematopoietic cells
    • PubMed ID: 20054088
    • Hidaka, M. et al. (2000) Gene trapping of two novel genes, Hzf and Hhl, expressed in hematopoietic cells. Mech Dev 90, 3–15, PubMed ID: 20054088
    • (2000) Mech Dev , vol.90 , pp. 3-15
    • Hidaka, M.1
  • 35
    • 0029004775 scopus 로고
    • Gene trap capture of a novel mouse gene, jumonji, required for neural tube formation
    • PubMed ID: 95278734
    • Takeuchi, T. et al. (1995) Gene trap capture of a novel mouse gene, jumonji, required for neural tube formation. Genes Dev 9, 1211–1222, PubMed ID: 95278734
    • (1995) Genes Dev , vol.9 , pp. 1211-1222
    • Takeuchi, T.1
  • 36
    • 0346980633 scopus 로고    scopus 로고
    • Exchangeable gene trap using the Cre/mutated lox system
    • PubMed ID: 99440754
    • Araki, K. et al. (1999) Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol 45, 737–750, PubMed ID: 99440754
    • (1999) Cell Mol Biol , vol.45 , pp. 737-750
    • Araki, K.1
  • 37
    • 0034598746 scopus 로고    scopus 로고
    • Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
    • PubMed ID: 20140121
    • Alizadeh, A.A. et al. (2000) Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 403, 503–511, PubMed ID: 20140121
    • (2000) Nature , vol.403 , pp. 503-511
    • Alizadeh, A.A.1
  • 38
    • 0033988749 scopus 로고    scopus 로고
    • Establishment of a gene-trap sequence tag library to generate mutant mice from embryonic stem cells
    • PubMed ID: 20082798
    • Wiles, M.V. et al. (2000) Establishment of a gene-trap sequence tag library to generate mutant mice from embryonic stem cells. Nat Genet 24, 13–14, PubMed ID: 20082798
    • (2000) Nat Genet , vol.24 , pp. 13-14
    • Wiles, M.V.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.