메뉴 건너뛰기




Volumn 61, Issue 4, 2012, Pages 884-888

Obesity is associated with high serotonin 4 receptor availability in the brain reward circuitry

Author keywords

Neuroimaging; Obesity; PET; Reward; Serotonin 4 receptor

Indexed keywords

CARBON 11; RADIOISOTOPE; SB 207145; SB 207145 C 11; SEROTONIN 4 RECEPTOR; UNCLASSIFIED DRUG;

EID: 84861338601     PISSN: 10538119     EISSN: 10959572     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2012.03.050     Document Type: Article
Times cited : (58)

References (48)
  • 2
    • 44649093192 scopus 로고    scopus 로고
    • Locomotor stimulation produced by 3,4-methylenedioxymethamphetamine (MDMA) is correlated with dialysate levels of serotonin and dopamine in rat brain
    • Baumann M.H., Clark R.D., Rothman R.B. Locomotor stimulation produced by 3,4-methylenedioxymethamphetamine (MDMA) is correlated with dialysate levels of serotonin and dopamine in rat brain. Pharmacol. Biochem. Behav. 2008, 90:208-217.
    • (2008) Pharmacol. Biochem. Behav. , vol.90 , pp. 208-217
    • Baumann, M.H.1    Clark, R.D.2    Rothman, R.B.3
  • 3
    • 46649106288 scopus 로고    scopus 로고
    • Affective neuroscience of pleasure: Reward in humans and animals
    • Berridge K.C., Kringelbach M.L. Affective neuroscience of pleasure: Reward in humans and animals. Psychopharmacology (Berl) 2008, 199:457-480.
    • (2008) Psychopharmacology (Berl) , vol.199 , pp. 457-480
    • Berridge, K.C.1    Kringelbach, M.L.2
  • 4
    • 77956180425 scopus 로고    scopus 로고
    • The tempted brain eats: Pleasure and desire circuits in obesity and eating disorders
    • Berridge K.C., Ho C.Y., Richard J.M., DiFeliceantonio A.G. The tempted brain eats: Pleasure and desire circuits in obesity and eating disorders. Brain Res. 2010, 1350:43-64.
    • (2010) Brain Res. , vol.1350 , pp. 43-64
    • Berridge, K.C.1    Ho, C.Y.2    Richard, J.M.3    DiFeliceantonio, A.G.4
  • 5
    • 0036627597 scopus 로고    scopus 로고
    • Multiple neural systems controlling food intake and body weight
    • Berthoud H.R. Multiple neural systems controlling food intake and body weight. Neurosci. Biobehav. Rev. 2002, 26:393-428.
    • (2002) Neurosci. Biobehav. Rev. , vol.26 , pp. 393-428
    • Berthoud, H.R.1
  • 6
    • 0028889089 scopus 로고
    • Neuroendocrine abnormalities in human obesity
    • Bjorntorp P. Neuroendocrine abnormalities in human obesity. Metabolism 1995, 44:38-41.
    • (1995) Metabolism , vol.44 , pp. 38-41
    • Bjorntorp, P.1
  • 7
    • 0026604767 scopus 로고
    • Serotonin and the biology of feeding
    • Blundell J.E. Serotonin and the biology of feeding. Am. J. Clin. Nutr. 1992, 55:155S-159S.
    • (1992) Am. J. Clin. Nutr. , vol.55
    • Blundell, J.E.1
  • 11
    • 0032817813 scopus 로고    scopus 로고
    • Role of serotonin(2A) and serotonin(2B/2C) receptor subtypes in the control of accumbal and striatal dopamine release elicited in vivo by dorsal raphe nucleus electrical stimulation
    • De Deurwaerdere P., Spampinato U. Role of serotonin(2A) and serotonin(2B/2C) receptor subtypes in the control of accumbal and striatal dopamine release elicited in vivo by dorsal raphe nucleus electrical stimulation. J. Neurochem. 1999, 73:1033-1042.
    • (1999) J. Neurochem. , vol.73 , pp. 1033-1042
    • De Deurwaerdere, P.1    Spampinato, U.2
  • 15
    • 78650031732 scopus 로고    scopus 로고
    • An approach for serotonin depletion in pigs: Effects on serotonin receptor binding
    • Ettrup A., Kornum B.R., Weikop P., Knudsen G.M. An approach for serotonin depletion in pigs: Effects on serotonin receptor binding. Synapse 2011, 65:136-145.
    • (2011) Synapse , vol.65 , pp. 136-145
    • Ettrup, A.1    Kornum, B.R.2    Weikop, P.3    Knudsen, G.M.4
  • 16
    • 14944374451 scopus 로고    scopus 로고
    • The Major Depression Inventory versus Schedules for Clinical Assessment in Neuropsychiatry in a population sample
    • Forsell Y. The Major Depression Inventory versus Schedules for Clinical Assessment in Neuropsychiatry in a population sample. Soc. Psychiatry Psychiatr. Epidemiol. 2005, 40:209-213.
    • (2005) Soc. Psychiatry Psychiatr. Epidemiol. , vol.40 , pp. 209-213
    • Forsell, Y.1
  • 17
    • 79952485836 scopus 로고    scopus 로고
    • Serotonin 5-HT4 receptors in the nucleus accumbens are specifically involved in the appetite suppressant and not locomotor stimulant effects of MDMA ('ecstasy')
    • Francis H.M., Kraushaar N.J., Hunt L.R., Cornish J.L. Serotonin 5-HT4 receptors in the nucleus accumbens are specifically involved in the appetite suppressant and not locomotor stimulant effects of MDMA ('ecstasy'). Psychopharmacology (Berl) 2010, 213:355-363.
    • (2010) Psychopharmacology (Berl) , vol.213 , pp. 355-363
    • Francis, H.M.1    Kraushaar, N.J.2    Hunt, L.R.3    Cornish, J.L.4
  • 18
    • 58149301316 scopus 로고    scopus 로고
    • Pharmacological targeting of the serotonergic system for the treatment of obesity
    • Garfield A.S., Heisler L.K. Pharmacological targeting of the serotonergic system for the treatment of obesity. J. Physiol. 2009, 587:49-60.
    • (2009) J. Physiol. , vol.587 , pp. 49-60
    • Garfield, A.S.1    Heisler, L.K.2
  • 19
    • 0029670162 scopus 로고    scopus 로고
    • 5-HT4 receptor-mediated modulation of 5-HT release in the rat hippocampus in vivo
    • Ge J., Barnes N.M. 5-HT4 receptor-mediated modulation of 5-HT release in the rat hippocampus in vivo. Br. J. Pharmacol. 1996, 117:1475-1480.
    • (1996) Br. J. Pharmacol. , vol.117 , pp. 1475-1480
    • Ge, J.1    Barnes, N.M.2
  • 20
    • 58149166684 scopus 로고    scopus 로고
    • Synthesis and evaluation of [11C]SB207145 as the first in vivo serotonin 5-HT4 receptor radioligand for PET imaging in man
    • Gee A.D., Martarello L., Passchier M. Synthesis and evaluation of [11C]SB207145 as the first in vivo serotonin 5-HT4 receptor radioligand for PET imaging in man. Curr. Radiopharm. 2008, 110-114.
    • (2008) Curr. Radiopharm. , pp. 110-114
    • Gee, A.D.1    Martarello, L.2    Passchier, M.3
  • 21
    • 58149163225 scopus 로고    scopus 로고
    • A highly flexible modular radiochemistry system [abstract]
    • (Suppl.)
    • Gillings N., Larsen P. A highly flexible modular radiochemistry system [abstract]. J. Labelled Compd. Radiopharm. 2005, 48:338. (Suppl.).
    • (2005) J. Labelled Compd. Radiopharm. , vol.48 , pp. 338
    • Gillings, N.1    Larsen, P.2
  • 25
    • 52949128037 scopus 로고    scopus 로고
    • A role for the 5-HT(1A), 5-HT4 and 5-HT6 receptors in learning and memory
    • King M.V., Marsden C.A., Fone K.C. A role for the 5-HT(1A), 5-HT4 and 5-HT6 receptors in learning and memory. Trends Pharmacol. Sci. 2008, 29:482-492.
    • (2008) Trends Pharmacol. Sci. , vol.29 , pp. 482-492
    • King, M.V.1    Marsden, C.A.2    Fone, K.C.3
  • 26
    • 0141625023 scopus 로고    scopus 로고
    • Activation of the human orbitofrontal cortex to a liquid food stimulus is correlated with its subjective pleasantness
    • Kringelbach M.L., O'Doherty J., Rolls E.T., Andrews C. Activation of the human orbitofrontal cortex to a liquid food stimulus is correlated with its subjective pleasantness. Cereb. Cortex 2003, 13:1064-1071.
    • (2003) Cereb. Cortex , vol.13 , pp. 1064-1071
    • Kringelbach, M.L.1    O'Doherty, J.2    Rolls, E.T.3    Andrews, C.4
  • 27
    • 33847609962 scopus 로고    scopus 로고
    • Serotonin and energy balance: Molecular mechanisms and implications for type 2 diabetes
    • Lam D.D., Heisler L.K. Serotonin and energy balance: Molecular mechanisms and implications for type 2 diabetes. Expert Rev. Mol. Med. 2007, 9:1-24.
    • (2007) Expert Rev. Mol. Med. , vol.9 , pp. 1-24
    • Lam, D.D.1    Heisler, L.K.2
  • 28
    • 0030468875 scopus 로고    scopus 로고
    • Simplified reference tissue model for PET receptor studies
    • Lammertsma A.A., Hume S.P. Simplified reference tissue model for PET receptor studies. Neuroimage 1996, 4:153-158.
    • (1996) Neuroimage , vol.4 , pp. 153-158
    • Lammertsma, A.A.1    Hume, S.P.2
  • 29
    • 0030774390 scopus 로고    scopus 로고
    • Selective breeding for diet-induced obesity and resistance in Sprague-Dawley rats
    • Levin B.E., Dunn-Meynell A.A., Balkan B., Keesey R.E. Selective breeding for diet-induced obesity and resistance in Sprague-Dawley rats. Am. J. Physiol. 1997, 273:R725-R730.
    • (1997) Am. J. Physiol. , vol.273
    • Levin, B.E.1    Dunn-Meynell, A.A.2    Balkan, B.3    Keesey, R.E.4
  • 30
    • 34247119203 scopus 로고    scopus 로고
    • CART peptides increase 5-hydroxytryptamine in the dorsal raphe and nucleus accumbens of freely behaving rats
    • Ma Z., Pearson E., Tao R. CART peptides increase 5-hydroxytryptamine in the dorsal raphe and nucleus accumbens of freely behaving rats. Neurosci. Lett. 2007, 417:303-307.
    • (2007) Neurosci. Lett. , vol.417 , pp. 303-307
    • Ma, Z.1    Pearson, E.2    Tao, R.3
  • 34
    • 75949117878 scopus 로고    scopus 로고
    • Diminished neural processing of aversive and rewarding stimuli during selective serotonin reuptake inhibitor treatment
    • McCabe C., Mishor Z., Cowen P.J., Harmer C.J. Diminished neural processing of aversive and rewarding stimuli during selective serotonin reuptake inhibitor treatment. Biol. Psychiatry 2010, 67:439-445.
    • (2010) Biol. Psychiatry , vol.67 , pp. 439-445
    • McCabe, C.1    Mishor, Z.2    Cowen, P.J.3    Harmer, C.J.4
  • 35
    • 0035879333 scopus 로고    scopus 로고
    • Involvement of human amygdala and orbitofrontal cortex in hunger-enhanced memory for food stimuli
    • Morris J.S., Dolan R.J. Involvement of human amygdala and orbitofrontal cortex in hunger-enhanced memory for food stimuli. J. Neurosci. 2001, 21:5304-5310.
    • (2001) J. Neurosci. , vol.21 , pp. 5304-5310
    • Morris, J.S.1    Dolan, R.J.2
  • 37
    • 34548627287 scopus 로고    scopus 로고
    • Serotonin decreases generation of dopaminergic neurons from mesencephalic precursors via serotonin type 7 and type 4 receptors
    • Parga J., Rodriguez-Pallares J., Munoz A., Guerra M.J., Labandeira-Garcia J.L. Serotonin decreases generation of dopaminergic neurons from mesencephalic precursors via serotonin type 7 and type 4 receptors. Dev. Neurobiol. 2007, 67:10-22.
    • (2007) Dev. Neurobiol. , vol.67 , pp. 10-22
    • Parga, J.1    Rodriguez-Pallares, J.2    Munoz, A.3    Guerra, M.J.4    Labandeira-Garcia, J.L.5
  • 38
    • 77957718322 scopus 로고    scopus 로고
    • Measuring endogenous 5-HT release by emission tomography: promises and pitfalls
    • Paterson L.M., Tyacke R.J., Nutt D.J., Knudsen G.M. Measuring endogenous 5-HT release by emission tomography: promises and pitfalls. J. Cereb. Blood Flow Metab. 2010, 30:1682-1706.
    • (2010) J. Cereb. Blood Flow Metab. , vol.30 , pp. 1682-1706
    • Paterson, L.M.1    Tyacke, R.J.2    Nutt, D.J.3    Knudsen, G.M.4
  • 40
    • 0036886022 scopus 로고    scopus 로고
    • Central serotonin4 receptors selectively regulate the impulse-dependent exocytosis of dopamine in the rat striatum: In vivo studies with morphine, amphetamine and cocaine
    • Porras G., Di Matteo V., De Deurwaerdere P., Esposito E., Spampinato U. Central serotonin4 receptors selectively regulate the impulse-dependent exocytosis of dopamine in the rat striatum: In vivo studies with morphine, amphetamine and cocaine. Neuropharmacology 2002, 43:1099-1109.
    • (2002) Neuropharmacology , vol.43 , pp. 1099-1109
    • Porras, G.1    Di Matteo, V.2    De Deurwaerdere, P.3    Esposito, E.4    Spampinato, U.5
  • 41
    • 84866732101 scopus 로고    scopus 로고
    • Cerebral markers of the serotonergic system in rat models of obesity and after Roux-en-Y gastric bypass
    • in press, Obesity (Silver Spring). 2012 (Mar 26).
    • Ratner, C., Ettrup, A., Bueter, M., Haahr, M.E., Compan, V., LeRoux, C., Levin, B.E., Hansen, H., Knudsen, G.M., in press. Cerebral markers of the serotonergic system in rat models of obesity and after Roux-en-Y gastric bypass. Obesity (Silver Spring). 2012 (Mar 26). http://dx.doi.org/10.1038/oby.2012.75.
    • Ratner, C.1    Ettrup, A.2    Bueter, M.3    Haahr, M.E.4    Compan, V.5    LeRoux, C.6    Levin, B.E.7    Hansen, H.8    Knudsen, G.M.9
  • 42
    • 19744374590 scopus 로고    scopus 로고
    • Taste, olfactory, and food texture processing in the brain, and the control of food intake
    • Rolls E.T. Taste, olfactory, and food texture processing in the brain, and the control of food intake. Physiol. Behav. 2005, 85:45-56.
    • (2005) Physiol. Behav. , vol.85 , pp. 45-56
    • Rolls, E.T.1
  • 43
    • 0029935734 scopus 로고    scopus 로고
    • The concentrations of monoamine metabolites and neuropeptides in the cerebrospinal fluid of obese women with different body fat distribution
    • Strombom U., Krotkiewski M., Blennow K., Mansson J.E., Ekman R., Bjorntorp P. The concentrations of monoamine metabolites and neuropeptides in the cerebrospinal fluid of obese women with different body fat distribution. Int. J. Obes. Relat. Metab. Disord. 1996, 20:361-368.
    • (1996) Int. J. Obes. Relat. Metab. Disord. , vol.20 , pp. 361-368
    • Strombom, U.1    Krotkiewski, M.2    Blennow, K.3    Mansson, J.E.4    Ekman, R.5    Bjorntorp, P.6
  • 45
    • 0042349489 scopus 로고    scopus 로고
    • Distribution of 5-HT4 receptors in the postmortem human brain-An autoradiographic study using [125I]SB 207710
    • Varnas K., Halldin C., Pike V.W., Hall H. Distribution of 5-HT4 receptors in the postmortem human brain-An autoradiographic study using [125I]SB 207710. Eur. Neuropsychopharmacol. 2003, 13:228-234.
    • (2003) Eur. Neuropsychopharmacol. , vol.13 , pp. 228-234
    • Varnas, K.1    Halldin, C.2    Pike, V.W.3    Hall, H.4
  • 48
    • 65949118888 scopus 로고    scopus 로고
    • Differential contributions of dopamine and serotonin to orbitofrontal cortex function in the marmoset
    • Walker S.C., Robbins T.W., Roberts A.C. Differential contributions of dopamine and serotonin to orbitofrontal cortex function in the marmoset. Cereb. Cortex 2009, 19:889-898.
    • (2009) Cereb. Cortex , vol.19 , pp. 889-898
    • Walker, S.C.1    Robbins, T.W.2    Roberts, A.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.