Luminal cholinergic signalling in airway lining fluid: A novel mechanism for activating chloride secretion via Ca 2+-dependent Cl - and K + channels

British Journal of Pharmacology

Volumn 166, Issue 4, 2012, Pages 1388-1402

  Hollenhorst, Monika I ^a   Lips, Katrin S ^a,b   Wolff, Miriam ^b   Wess, Jürgen ^c   Gerbig, Stefanie ^a   Takats, Zoltan ^a   Kummer, Wolfgang ^b   Fronius, Martin ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b JUSTUS LIEBIG UNIVERSITY GIESSEN   (Germany)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

acetylcholine; acetylcholine receptors; airway epithelium; auto paracrine; muscarinic receptors; nicotinic receptors; non neuronal cholinergic system; transepithelial ion transport

Indexed keywords

AMILORIDE; CALCIMYCIN; CALCIUM ACTIVATED POTASSIUM CHANNEL; CHLORIDE; CHOLINERGIC RECEPTOR; MUSCARINE; MUSCARINIC M1 RECEPTOR; MUSCARINIC M3 RECEPTOR; NICOTINE; NIFLUMIC ACID; ORGANIC CATION TRANSPORTER 1; ORGANIC CATION TRANSPORTER 2; ORGANIC CATION TRANSPORTER 3; POTASSIUM CHANNEL BLOCKING AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CHOLINERGIC SYSTEM; CONTROLLED STUDY; DESORPTION; ELECTROSPRAY MASS SPECTROMETRY; ENZYME ACTIVATION; EPITHELIUM CELL; GENETIC TRANSCRIPTION; INTRACELLULAR SIGNALING; ION CURRENT; ION TRANSPORT; LUNG FLUID; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRACHEA;

ACETYLCHOLINE; ANIMALS; BODILY SECRETIONS; CATECHOLAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; CELLS, CULTURED; CHLORIDE CHANNELS; CHOLINE O-ACETYLTRANSFERASE; CHOLINERGIC AGONISTS; GENE EXPRESSION; MEMBRANE POTENTIALS; MEMBRANE TRANSPORT MODULATORS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; ORGANIC CATION TRANSPORT PROTEINS; ORGANIC CATION TRANSPORTER 1; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; PROTEIN ISOFORMS; RECEPTOR, MUSCARINIC M1; RECEPTOR, MUSCARINIC M3; RESPIRATORY MUCOSA; TRACHEA;

EID: 84861327184     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2012.01883.x     Document Type: Article

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