Inhibitory effect of DIDS, NPPB, and phloretin on intracellular chloride channels

Pflugers Archiv European Journal of Physiology

Volumn 455, Issue 2, 2007, Pages 349-357

  Malekova, Lubica ^a   Tomaskova, Jana ^b   Novakova, Marie ^c   Stefanik, Peter ^a   Kopacek, Juraj ^b   Lakatos, Boris ^d   Pastorekova, Silvia ^b   Krizanova, Olga ^a   Breier, Albert ^a   Ondrias, Karol ^a  

^a INSTITUTE OF MOLECULAR PHYSIOLOGY AND GENETICS   (Slovakia)

^b INSTITUTE OF VIROLOGY   (Slovakia)

^c MASARYK UNIVERSITY   (Czech Republic)

^d SLOVAK UNIVERSITY OF TECHNOLOGY   (Slovakia)

Author keywords

Apoptosis; Cardiac myocytes; Chloride conductance; Cl channels; Mitochondria; Single channel

Indexed keywords

5 NITRO 2 (3 PHENYLPROPYLAMINO)BENZOIC ACID; BONGKREKIC ACID; CARBOXYATRACTYLOSIDE; CHLORIDE CHANNEL; DIHYDRO 4,4' DIISOTHIOCYANO 2,2' STILBENEDISULFONIC ACID; PHLORETIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; BILAYER MEMBRANE; CELL MEMBRANE CONDUCTANCE; CELL MEMBRANE PERMEABILITY; CHANNEL GATING; CONCENTRATION RESPONSE; CONTROLLED STUDY; HEART CELL CULTURE; HEART MITOCHONDRION; HEART MUSCLE CELL; LIPID MEMBRANE; LYSOSOME; MALE; MEMBRANE VESICLE; NONHUMAN; PRIORITY JOURNAL; PROBABILITY; RAT;

4,4'-DIISOTHIOCYANOSTILBENE-2,2'-DISULFONIC ACID; ANIMALS; APOPTOSIS; CELLS, CULTURED; CHLORIDE CHANNELS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHYSIOLOGY; HYDROGEN PEROXIDE; LYSOSOMES; MALE; MITOCHONDRIA, HEART; MYOCYTES, CARDIAC; NITROBENZOATES; PHLORETIN; RATS; RATS, WISTAR;

EID: 35148833049     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-007-0300-9     Document Type: Article

References (37)

1. Akao M, O'Rourke B, Teshima Y, Seharaseyon J, Marban E (2003) Mechanistically distinct steps in the mitochondrial death pathway triggered by oxidative stress in cardiac myocytes. Circ Res 92:186-194
2. Arnould T, Mercy L, Houbion A, Vankoningsloo S, Renard P, Pascal T, Ninane N, Demazy C, Raes M (2003) mtCLIC is up-regulated and maintains a mitochondrial membrane potential in tDNA-depleted L929 cells. FASEB J 17:2145-2147
3. Beavis AD (1994) A channel model to explain regulation of the mitochondrial inner membrane anion channel (IMAC). In: Forte M, Colombini M (eds) Molecular biology of mitochondrial transport systems (NATO ASI series), vol. H 83. Springer, Berlin Heidelberg New York, pp 137-151
4. Beavis AD, Davatol-Hag H (1996) The mitochondrial inner membrane anion channel is inhibited by DIDS. J Bioenerg Biomembr 28:207-214
5. + antiporters. Arch Biochem Biophys 264:417-427
6. Chandel NS, McClintock DS, Feliciano CE, Wood TM, Melendez JA, Rodriguez AM, Schumacker PT (2000) Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing. J Biol Chem 275:25130-25138
7. Fernandez-Salas E, Sagar M, Cheng C, Yuspa SH, Weinberg WC (1999) p53 and tumor necrosis factor alpha regulate the expression of a mitochondrial chloride channel protein. J Biol Chem 274:36488-36497
8. Fernandez-Salas E, Suh KS, Speransky VV, Bowers WL, Levy JM, Adams T, Pathak KR, Edwards LE, Hayes DD, Cheng C, Steven AC, Weinberg WC, Yuspa SH (2002) mtCLIC/CLIC4, an organellular chloride channel protein, is increased by DNA damage and participates in the apoptotic response to p53. Mol Cell Biol 22:3610-3620
9. Fliss H, Gattinger D (1996) Apoptosis in ischemic and reperfused rat myocardium. Circ Res 79:949-956
10. Fujita H, Ishizaki Y, Yanagisawa A, Morita I, Murota S, Ishikawa K (1999) Possible involvement of a chloride-bicarbonate exchanger in apoptosis of endothelial cells and cardiomyocytes. Cell Biol Int 23:241-249
11. Hayman KA, Spurway TD, Ashley RH (1993) Single anion channels reconstituted from cardiac mitoplasts. J Membr Biol 136:181-190
12. Hishita T, Tada-Oikawa S, Tohyama K, Miura Y, Nishihara T, Tohyama Y, Yoshida Y, Uchiyama T, Kawanishi S (2001) Caspase-3 activation by lysosomal enzymes in cytochrome c-independent apoptosis in myelodysplastic syndrome-derived cell line P391. Cancer Res 61:2878-2884
13. Huang SG, Klingenberger M (1996) Chloride channel properties of the uncoupling protein from brown adipose tissue mitochondria: a patch-clamp study. Biochemistry 35:16806-16814
14. - channel in cisplatin-induced apoptosis in human epidermoid cancer cells. J Membr Biol 205:139-145
15. James TN (1994) Normal and abnormal consequences of apoptosis in the human heart. From postnatal morphogenesis to paroxysmal arrhythmias. Circulation 90:556-573
16. Jiao J-D, Xu CQ, Yue P, Dong D-L, Li Z, Du Z-M, Yang BF (2006) Volume-sensitive outwardly rectifying chloride channels are involved in oxidative stress-induced apoptosis of mesangial cells. Biochem Biophys Res Commun 340:277-285
17. Kawano H, Okada R, Kawano Y, Sueyoshi N, Shirai T (1994) Apoptosis in acute and chronic myocarditis. Jpn Heart J 35:745-750
18. Madesh M, Hajnoczky G (2001) VDAC-dependent permeabilization of the outer mitochondrial membrane by superoxide induces rapid and massive cytochrome c release. J Cell Biol 155:1003-1015
19. Malekova L, Kominkova V, Ferko M, Stefanik P, Krizanova O, Ziegelhoffer A, Szewczyk A, Ondrias K (2007) Bongkrekic acid and atractyloside inhibits chloride channels from mitochondrial membranes of rat heart. Biochim Biophys Acta 1767:31-44
20. Matulef K, Maduke M (2005) Side-dependent inhibition of a prokaryotic ClC by DIDS. Biophys J 89:1721-1730
21. Miller C, White MM (1980) A voltage-dependent chloride conductance channel from Torpedo electroplax membrane. Ann N Y Acad Sci 341:534-551
22. 2+ overload during simulated ischemia and reperfusion: possible mechanism of cardioprotection. Circ Res 89:891-898
23. Okada Y, Maeno E (2001) Apoptosis, cell volume regulation and volume-regulatory chloride channels. Comp Biochem Physiol A Mol Integr Physiol 130:377-383
24. Okada Y, Shimizu T, Maeno E, Tanabe S, Wang X, Takahashi N (2006) Volume-sensitive chloride channels involved in apoptotic volume decrease and cell death. J Membr Biol 209:1-9
25. Panduri V, Weitzman SA, Chandel NS, Kamp DW (2004) Mitochondrial-derived free radicals mediate asbestos-induced alveolar epithelial cell apoptosis. Am J Physiol Lung Cell Mol Physiol 286:L1220-L1227
26. Paucek P, Yarov-Yarovoy V, Sun X, Garlid KD (1996) Inhibition of the mitochondrial KATP channel by long-chain acyl-CoA esters and activation by guanine nucleotides. J Biol Chem 271:32084-32088
27. Petrosillo G, Ruggiero FM, Paradies G (2003) Role of reactive oxygen species and cardiolipin in the release of cytochrome c from mitochondria. FASEB J 17:2202-2208
28. Picollo A, Liantonio A, Didonna MP, Elia L, Camerino DC, Pusch M (2004) Molecular determinants of differential pore blocking of kidney CLC-K chloride channels. EMBO Rep 5:584-589
29. Saraste A, Pulkki K, Kallajoki M, Henriksen K, Parvinen M, Voipio-Pulkki LM (1997) Apoptosis in human acute myocardial infarction. Circulation 95:320-323
30. Schlesinger PH, Gross A, Yin X-M, Yamamoto K, Saito M, Waksman G, Korsmeyer SJ (1997) Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2. Proc Natl Acad Sci USA 94:11357-11362
31. Stefanelli C, Stanic I, Zini M, Bonavita F, Flamigni F, Zambonin L, Landi L, Pignatti C, Guarnieri C, Caldarera CM (2000) Polyamines directly induce release of cytochrome c from heart mitochondria. Biochem J 347:875-880
32. Tanabe S, Wang X, Takahashi N, Uramoto H, Okada Y (2005) HCO(3)(-)-independent rescue from apoptosis by stilbene derivatives in rat cardiomyocytes. FEBS Lett 579:517-522
33. Tillinger A, Novakova M, Pavlovicova M, Lacinova L, Zatovicova M, Pastorekova S, Krizanova O, Kvetnansky R (2006) Modulation by 6-hydroxydopamine of expression of the phenylethanolamine N-methyltransferase (PNMT) gene in the rat heart during immobilization stress. Stress 9:207-213
34. Wang X, Takahashi N, Uramoto H, Okada Y (2005) Chloride channel inhibition prevents ROS-dependent apoptosis induced by ischemia-reperfusion in mouse cardiomyocytes. Cell Physiol Biochem 16:147-154
35. Wattiaux R, Wattiaux-De Cininck S, Thirion J, Gasingirwa MC, Jadot M (2007) Lysosomes and Fas mediated liver cell death. Biochem J 403:89-95
36. + overload is caused by oxidative stress and leads to activation of the caspase 3-dependent apoptotic machinery. FASEB J 18:1442-1444
37. Zang Y, Beard RL, Chandraratna RAS, Kang JX (2001) Evidence of a lysosomal pathway for apoptosis induced by the synthetic retinoid CD437 in human leukemia HL-60 cells. Cell Death Differ 8:477-485