Pharmacokinetics and pharmacodynamics of medication in asphyxiated newborns during controlled hypothermia. The PharmaCool multicenter study

BMC Pediatrics

Volumn 12, Issue , 2012, Pages

  de Haan, Timo R ^a,l   Bijleveld, Yuma A ^l   van der Lee, Johanna H ^b   Groenendaal, Floris ^c   van den Broek, Marcel P H ^c   Rademaker, Carin M A ^c   van Straaten, Henrica L M ⁱ   van Weissenbruch, Mirjam M ^k   Vermeulen, Jeroen R ^k   Dijk, Peter H ^d   Dudink, Jeroen ^g   Rijken, Monique ^j   van Heijst, Arno ^e   Dijkman, Koen P ^h   Gavilanes, Danilo ^f   van Kaam, Anton H ^a   Offringa, Martin ^a,b   Mathôt, Ron A A ^l  

^a EMMA CHILDREN S HOSPITAL   (Netherlands)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^d UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^e RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^f MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^g SOPHIA CHILDREN S HOSPITAL   (Netherlands)

^h MÁXIMA MEDICAL CENTER   (Netherlands)

ⁱ ISALA HOSPITAL   (Netherlands)

^j LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^k VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^l ACADEMIC MEDICAL CENTER   (Netherlands)

more..

Author keywords

Drug dosing; Drug monitoring; Evidence based; Guideline; Perinatal asphyxia; Pharmacokinetic research; Therapeutic hypothermia

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; AMIKACIN; AMOXICILLIN; ANALGESIC AGENT; ANTIBIOTIC AGENT; ANTICONVULSIVE AGENT; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; C REACTIVE PROTEIN; CEFTAZIDIME; CREATININE; FENTANYL; GENTAMICIN; LACTIC ACID; LIDOCAINE; MIDAZOLAM; MORPHINE; PENICILLIN G; PHENOBARBITAL; SEDATIVE AGENT; UREA; VANCOMYCIN; DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALBUMIN BLOOD LEVEL; ANALGESIA; ARTERIAL GAS; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; BLOOD CULTURE; BLOOD SAMPLING; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG METABOLISM; DRUG MONITORING; HUMAN; HYPOTHERMIA; HYPOXIC ISCHEMIC ENCEPHALOPATHY; INDUCED HYPOTHERMIA; LACTATE BLOOD LEVEL; MINIMUM INHIBITORY CONCENTRATION; MULTICENTER STUDY (TOPIC); NEWBORN; NEWBORN HYPOXIA; OBSERVATIONAL STUDY; PAIN ASSESSMENT; PATHOGEN CLEARANCE; PROSPECTIVE STUDY; SEDATION; URINALYSIS; BLOOD; CLINICAL PROTOCOL; CLINICAL TRIAL; COHORT ANALYSIS; DRUG EFFECT; ELECTROENCEPHALOGRAPHY; FEMALE; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; METHODOLOGY; MULTICENTER STUDY; NEWBORN INTENSIVE CARE; PHARMACOKINETICS; PHARMACOLOGY; RESUSCITATION; TREATMENT OUTCOME; WARMING;

ASPHYXIA NEONATORUM; CHROMATOGRAPHY, LIQUID; CLINICAL PROTOCOLS; COHORT STUDIES; ELECTROENCEPHALOGRAPHY; FEMALE; HUMANS; HYPOTHERMIA, INDUCED; HYPOXIA-ISCHEMIA, BRAIN; INFANT, NEWBORN; INTENSIVE CARE UNITS, NEONATAL; INTENSIVE CARE, NEONATAL; MALE; MASS SPECTROMETRY; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS; PHARMACOLOGY; RESUSCITATION; REWARMING; TREATMENT OUTCOME;

EID: 84861325575     PISSN: None     EISSN: 14712431     Source Type: Journal    
DOI: 10.1186/1471-2431-12-45     Document Type: Article

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