Establishment of a human nonluteinized granulosa cell line that transitions from the gonadotropin-independent to the gonadotropin-dependent status

Endocrinology

Volumn 153, Issue 6, 2012, Pages 2851-2860

  Bayasula, ^a   Iwase, Akira ^a   Kiyono, Tohru ^b   Takikawa, Sachiko ^a   Goto, Maki ^a   Nakamura, Tomoko ^a   Nagatomo, Yoshinari ^a   Nakahara, Tatsuo ^a   Kotani, Tomomi ^a   Kobayashi, Hiroharu ^a   Kondo, Mika ^a   Manabe, Shuichi ^a   Kikkawa, Fumitaka ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN A; ANDROSTENEDIOL; AROMATASE; BETA ACTIN; BONE MORPHOGENETIC PROTEIN 15; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN 6; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CYCLIN D1; CYCLIN DEPENDENT KINASE 4; ESTRADIOL; FOLLITROPIN; FOLLITROPIN RECEPTOR; GONADOTROPIN; GONADOTROPIN RECEPTOR; GROWTH DIFFERENTIATION FACTOR 9; LENTIVIRUS VECTOR; MESSENGER RNA; MUELLERIAN INHIBITING FACTOR; OSTEOGENIC PROTEIN 1; PROTEIN E6; PROTEIN P16; SMAD1 PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; STEROIDOGENIC ACUTE REGULATORY PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNINDEXED DRUG;

ADULT; AROMATIZATION; ARTICLE; CELL IMMORTALIZATION; CELL TYPE; CONTROLLED STUDY; DEVELOPMENTAL STAGE; FEMALE; GRANULOSA CELL; HORMONAL REGULATION; HUMAN; HUMAN CELL; OOCYTE; OVARY FOLLICLE DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN PHOSPHORYLATION; STEROIDOGENESIS; THECA CELL; UPREGULATION; VIRAL GENE DELIVERY SYSTEM; WESTERN BLOTTING;

ACTIVINS; ADULT; AROMATASE; BLOTTING, WESTERN; BONE MORPHOGENETIC PROTEINS; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; FEMALE; FOLLICLE STIMULATING HORMONE; GENE EXPRESSION; GONADOTROPINS; GRANULOSA CELLS; HUMANS; PHOSPHOPROTEINS; PHOSPHORYLATION; RECEPTORS, GONADOTROPIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA;

EID: 84861322271     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2011-1810     Document Type: Article

References (40)

1. Monniaux D, Pisselet C 1992 Control of proliferation and differentiation of ovine granulosa cells by insulin-like growth factor-I and follicle-stimulating hormone in vitro. Biol Reprod 46:109-119
2. Krysko DV, Diez-Fraile A, Criel G, Svistunov AA, Vandenabeele P, D'Herde K 2008 Life and death of female gametes during oogenesis and folliculogenesis. Apoptosis 13:1065-1087
3. Voutilainen R, Tapanainen J, Chung BC, Matteson KJ, Miller WL 1986 Hormonal regulation of P450scc (20,22-desmolase) and P450c17 (17 α-hydroxylase/17,20-lyase) in cultured human granulosa cells. J Clin Endocrinol Metab 63:202-207 (Pubitemid 16093032)
4. Schipper I, Fauser BC, van Gaver EB, Zarutskie PW, Dahl KD 1993 Development of a human granulosa cell culture model with follicle stimulating hormone responsiveness. Hum Reprod 8:1380-1386 (Pubitemid 23265966)
5. Goto M, Iwase A, Harata T, Takigawa S, Suzuki K, Manabe S, Kikkawa F 2009 IGF1-induced AKT phosphorylation and cell proliferation are suppressed with the increase in PTEN during luteinization in human granulosa cells. Reproduction 137:835-842
6. Iwase A, Goto M, Harata T, Takigawa S, Nakahara T, Suzuki K, Manabe S, Kikkawa F 2009 Insulin attenuates the insulin-like growth factor-I (IGF-I)-Akt pathway, not IGF-I-extracellularly regulated kinase pathway, in luteinized granulosa cells with an increase in PTEN. J Clin Endocrinol Metab 94:2184-2191
7. Stocco C, Telleria C, GiboriG2007 The molecular control of corpus luteum formation, function, and regression. Endocr Rev 28:117-149 (Pubitemid 46220852)
8. Havelock JC, Rainey WE, Carr BR 2004 Ovarian granulosa cell lines. Mol Cell Endocrinol 228:67-78 (Pubitemid 39482520)
9. Ishiwata I, Ishiwata C, Soma M, Kobayashi N, Ishikawa H 1984 Establishment and characterization of an estrogen-producing human ovarian granulosa tumor cell line. J Natl Cancer Inst 72:789-800 (Pubitemid 14131719)
10. Nishi Y, Yanase T, Mu Y, Oba K, Ichino I, Saito M, Nomura M, Mukasa C, Okabe T, Goto K, Takayanagi R, Kashimura Y, Haji M, Nawata H 2001 Establishment and characterization of a steroidogenic human granulosa-like tumor cell line, KGN, that expresses functional follicle-stimulating hormone receptor. Endocrinology 142:437-445 (Pubitemid 32183706)
11. van den Berg-Bakker CA, Hagemeijer A, Franken-Postma EM, Smit VT, Kuppen PJ, van Ravenswaay Claasen HH, Cornelisse CJ, Schrier PI 1993 Establishment and characterization of 7 ovarian carcinoma cell lines and one granulosa tumor cell line: growth features and cytogenetics. Int J Cancer 53:613-620 (Pubitemid 23069273)
12. Hosokawa K, Dantes A, Schere-Levy C, Barash A, Yoshida Y, Kotsuji F, Vlodavsky I, Amsterdam A 1998 Induction of Ad4BP/SF-1, steroidogenic acute regulatory protein, and cytochrome P450scc enzyme system expression in newly established human granulosa cell lines. Endocrinology 139:4679-4687 (Pubitemid 28487787)
13. Rainey WH, Sawetawan C, Shay JW, Michael MD, Mathis JM, Kutteh W, Byrd W, Carr BR 1994 Transformation of human granulosa cells with the E6 and E7 regions of human papillomavirus. J Clin Endocrinol Metab 78:705-710 (Pubitemid 24083315)
14. Tajima K, Hosokawa K, Yoshida Y, Dantes A, Sasson R, Kotsuji F, Amsterdam A 2002 Establishment of FSH-responsive cell lines by transfection of pre-ovulatory human granulosa cells with mutated p53 (p53val135) and Ha-ras genes. Mol Hum Reprod 8:48-57 (Pubitemid 34097662)
15. Schrader KA, Gorbatcheva B, Senz J, Heravi-Moussavi A, Melnyk N, Salamanca C, Maines-Bandiera S, Cooke SL, Leung P, Brenton JD, Gilks CB, Monahan J, Huntsman DG 2009 The specificity of the FOXL2 c. 402C>G somatic mutation: a survey of solid tumors. PLoS One 4:e7988
16. Kiyono T, Foster SA, Koop JI, McDougall JK, Galloway DA, Klingelhutz AJ 1998 Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells. Nature 396:84-88 (Pubitemid 28520454)
17. Okamoto T, Aoyama T, Nakayama T, Nakamata T, Hosaka T, Nishijo K, Nakamura T, Kiyono T, Toguchida J 2002 Clonal heterogeneity in differentiation potential of immortalized human mesenchymal stem cells. Biochem Biophys Res Commun 295:354-361 (Pubitemid 34785842)
18. Terai M, Uyama T, Sugiki T, Li XK, Umezawa A, Kiyono T 2005 Immortalization of human fetal cells: the life span of umbilical cord blood-derived cells can be prolonged without manipulating p16INK4a/RB braking pathway. Mol Biol Cell 16:1491-1499 (Pubitemid 40349582)
19. Tsuruga Y, Kiyono T, Matsushita M, Takahashi T, Kasai H, Matsumoto S, Todo S 2008 Establishment of immortalized human hepatocytes by introduction of HPV16 E6/E7 and hTERT as cell sources for liver cell-based therapy. Cell Transplant 17:1083-1094
20. Kyo S, Nakamura M, Kiyono T, Maida Y, Kanaya T, Tanaka M, Yatabe N, InoueM2003 Successful immortalization of endometrial glandular cells with normal structural and functional characteristics. Am J Pathol 163:2259-2269 (Pubitemid 37466470)
21. Sasaki R, Narisawa-Saito M, Yugawa T, Fujita M, Tashiro H, Katabuchi H, KiyonoT2009 Oncogenic transformation of human ovarian surface epithelial cells with defined cellular oncogenes. Carcinogenesis 30:423-431
22. Wölfel T, Hauer M, Schneider J, Serrano M, Wölfel C, Klehmann-Hieb E, De Plaen E, Hankeln T, Meyerzum Büschenfelde KH, Beach D 1995 A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma. Science 269:1281-1284
23. Miyoshi H, Blömer U, Takahashi M, Gage FH, Verma IM 1998 Development of a self-inactivating lentivirus vector. J Virol 72:8150-8157
24. Findlay JK 1993 An update on the roles of inhibin, activin, and follistatin as local regulators of folliculogenesis. Biol Reprod 48:15-23 (Pubitemid 23005206)
25. Nakamura M, Nakamura K, Igarashi S, Tano M, Miyamoto K, Ibuki Y, Minegishi T 1995 Interaction between activinAand cAMP in the induction of FSH receptor in cultured rat granulosa cells. J Endocrinol 147:103-110
26. Knight PG, Glister C 2006 TGF-β superfamily members and ovarian follicle development. Reproduction 132:191-206 (Pubitemid 44274724)
27. Trombly DJ, Woodruff TK, Mayo KE 2009 Roles for transforming growth factor β superfamily proteins in early folliculogenesis. Semin Reprod Med 27:14-23
28. Shiomi K, Kiyono T, Okamura K, Uezumi M, Goto Y, Yasumoto S, Shimizu S, Hashimoto N 2011 CDK4 and cyclin D1 allow human myogenic cells to recapture growth property without compromising differentiation potential. Gene Ther 18:857-866
29. Zushi Y, Narisawa-Saito M, Noguchi K, Yoshimatsu Y, Yugawa T, Egawa N, Fujita M, Urade M, Kiyono T 2011 An in vitro multistep carcinogenesis model for both HPV-positive and -negative human oral squamous cell carcinomas. Am J Cancer Res 1:869-881
30. Elvin JA, Matzuk MM 1998 Mouse models of ovarian failure. Rev Reprod 3:183-195 (Pubitemid 28508649)
31. Richards JS 1980 Maturation of ovarian follicles: actions and interactions of pituitary and ovarian hormones on follicular cell differentiation. Physiol Rev 60:51-89 (Pubitemid 10104511)
32. NakamuraK, Minegishi T, Takakura Y,MiyamotoK, Hasegawa Y, Ibuki Y, Igarashi M 1991 Hormonal regulation of gonadotropin receptor mRNA in rat ovary during follicular growth and luteinization. Mol Cell Endocrinol 82:259-263
33. Yaron Y, Schwartz D, Evans MI, Lessing JB, Rotter V 1998 Alternatively spliced mRNA transcripts encoding the extracellular domain of the FSH receptor gene. Expression in the mouse ovary during the ovulatory cycle. J Reprod Med 43:435-438 (Pubitemid 28244009)
34. Murphy BD 2000 Models of luteinization. Biol Reprod 63:2-11 (Pubitemid 30429378)
35. Galloway SM, McNatty KP, Cambridge LM, Laitinen MP, Juengel JL, Jokiranta TS, McLaren RJ, Luiro K, Dodds KG, Montgomery GW, Beattie AE, Davis GH, Ritvos O 2000 Mutations in an oocytederived growth factor gene (BMP15) cause increased ovulation rate and infertility in a dosage-sensitive manner. Nat Genet 25:279-283 (Pubitemid 30437312)
36. Yan C, Wang P, DeMayo J, DeMayo FJ, Elvin JA, Carino C, Prasad SV, Skinner SS, Dunbar BS, Dube JL, Celeste AJ, Matzuk MM 2001 Synergistic roles of bone morphogenetic protein 15 and growth differentiation factor 9 in ovarian function. Mol Endocrinol 15:854-866 (Pubitemid 32510635)
37. Mazerbourg S, Hsueh AJ 2006 Genomic analyses facilitate identification of receptors and signalling pathways for growth differentiation factor 9 and related orphan bone morphogenetic protein/growth differentiation factor ligands.HumReprod Update 12:373-383 (Pubitemid 43923412)
38. Miyazawa K, Shinozaki M, Hara T, Furuya T, Miyazono K 2002 Two major Smad pathways in TGF-β superfamily signalling. Genes Cells 7:1191-1204 (Pubitemid 36024597)
39. Fan HY, Liu Z, Cahill N, Richards JS 2008 Targeted disruption of Pten in ovarian granulosa cells enhances ovulation and extends the life span of luteal cells. Mol Endocrinol 22:2128-2140
40. Fan HY, Liu Z, Shimada M, Sterneck E, Johnson PF, Hedrick SM, Richards JS 2009 MAPK3/1 (ERK1/2) in ovarian granulosa cells are essential for female fertility. Science 324:938-941