Quantitative pancreatic β cell MRI using manganese-enhanced Look-Locker imaging and two-site water exchange analysis

Magnetic Resonance in Medicine

Volumn 67, Issue 6, 2012, Pages 1730-1739

  Antkowiak, Patrick F ^a   Vandsburger, Moriel H ^a   Epstein, Frederick H ^a,b  

^a University of Virginia   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

Author keywords

diabetes; manganese; MRI; pancreatic cell

Indexed keywords

CELLS; CYTOLOGY; MAGNETIC RESONANCE IMAGING; MAMMALS; MANGANESE; MANGANESE COMPOUNDS; MEDICAL PROBLEMS; RATE CONSTANTS;

BETA CELL FUNCTIONS; INTRACELLULAR WATER; MONOEXPONENTIAL MODELS; PANCREATIC BETA CELLS; PHARMACOLOGICAL TREATMENT; PROTON RELAXATION; WATER EXCHANGE; WATER EXCHANGE MODEL;

MANGANESE REMOVAL (WATER TREATMENT);

CALCIUM; CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; DIAZOXIDE; GLUCOSE; GLUCOSE TRANSPORTER 2; MANGANESE; MANGANESE CHLORIDE; NIFEDIPINE; POTASSIUM CHANNEL; SODIUM CHLORIDE; TOLBUTAMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL FUNCTION; CELL LABELING; CELL STIMULATION; COMPARTMENT MODEL; CONTROLLED STUDY; DIABETES MELLITUS; DIET RESTRICTION; DISEASE COURSE; DRUG EFFECT; IMAGE ANALYSIS; IMAGING SYSTEM; INSULIN RELEASE; MALE; MANGANESE ENHANCED LOOK LOCKER IMAGING; MATHEMATICAL MODEL; MONITORING; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PANCREAS ISLET BETA CELL; QUANTITATIVE ANALYSIS; TREATMENT OUTCOME; TWO SITE WATER EXCHANGE ANALYSIS;

EID: 84861232214     PISSN: 07403194     EISSN: 15222594     Source Type: Journal    
DOI: 10.1002/mrm.23139     Document Type: Article

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