Preliminary assessment of cardiac short term safety and efficacy of manganese chloride for cardiovascular magnetic resonance in humans

Journal of Cardiovascular Magnetic Resonance

Volumn 13, Issue 1, 2011, Pages

  Fernandes, Juliano L ^a   Storey, Pippa ^b   Da Silva, Jose Alvaro ^c   De Figueiredo, Gabriel S ^c   Kalaf, Jose M ^c   Coelho, Otavio R ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b NEW YORK UNIVERSITY   (United States)

^c Radiologia Clinica de Campinas   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

MANGANESE CHLORIDE; RADIOACTIVE MATERIAL; CHLORIDE; CONTRAST MEDIUM; DIAGNOSTIC AGENT; MANGANESE DERIVATIVE;

ACCURACY; ADULT; ARTICLE; BREATH HOLDING; CARDIOVASCULAR MAGNETIC RESONANCE; CLINICAL EVALUATION; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; FEMALE; FLUSHING; HEART FUNCTION; HEART MUSCLE ISCHEMIA; HEART RATE; HUMAN; HUMAN EXPERIMENT; MALE; MEDICAL RESEARCH; NORMAL HUMAN; PRIORITY JOURNAL; SIDE EFFECT; SIGNAL NOISE RATIO; SYSTOLIC BLOOD PRESSURE; VOLUNTEER; BLOOD PRESSURE; BRAZIL; COMPUTER ASSISTED DIAGNOSIS; HEART; HEART LEFT VENTRICLE FUNCTION; HEART STROKE VOLUME; HISTOLOGY; INTRAVENOUS DRUG ADMINISTRATION; METHODOLOGY; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE IMAGING; PHYSIOLOGY; PILOT STUDY; PREDICTIVE VALUE; PROSPECTIVE STUDY; RISK ASSESSMENT; TIME;

ADULT; BLOOD PRESSURE; BRAZIL; CHLORIDES; CONTRAST MEDIA; FEMALE; HEART; HEART RATE; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; INFUSIONS, INTRAVENOUS; MAGNETIC RESONANCE IMAGING, CINE; MALE; MANGANESE COMPOUNDS; MIDDLE AGED; PILOT PROJECTS; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; RISK ASSESSMENT; STROKE VOLUME; TIME FACTORS; VENTRICULAR FUNCTION, LEFT;

EID: 79953303697     PISSN: 10976647     EISSN: 1532429X     Source Type: Journal    
DOI: 10.1186/1532-429X-13-6     Document Type: Article

References (35)

1. Cardiovascular magnetic resonance imaging: current and emerging applications. Lima JA, Desai MY, J Am Coll Cardiol 2004 44 1164 1171 10.1016/j.jacc.2004.06.033 15364314 (Pubitemid 39208868)
2. Role of cardiac magnetic resonance imaging in the assessment of myocardial viability. Shan K, Constantine G, Sivananthan M, Flamm SD, Circulation 2004 109 1328 1334 10.1161/01.CIR.0000120294.67948.E3 15037539 (Pubitemid 38387815)
3. Update on nephrogenic systemic fibrosis. Thomsen HS, Marckmann P, Logager VB, Magn Reson Imaging Clin N Am 2008 16 551 560 vii 10.1016/j.mric.2008.07.011 18926421
4. Contrast-enhanced cardiac MR imaging. Schneider G, Fries P, Ahlhelm F, Kindermann I, Kramann B, Bohm M, Eur Radiol 2003 13 Suppl 3 11 18 10.1007/s00330-003-0002-4 15015876 (Pubitemid 38072466)
5. Manganese enhanced magnetic resonance imaging. Lee JH, Koretsky AP, Curr Pharm Biotechnol 2004 5 529 537 10.2174/1389201043376607 15579042 (Pubitemid 39654850)
6. Manganese-enhanced magnetic resonance imaging (MEMRI). Koretsky AP, Silva AC, NMR Biomed 2004 17 527 531 10.1002/nbm.940 15617051 (Pubitemid 40124778)
7. Determining canine myocardial area at risk with manganese-enhanced MR imaging. Natanzon A, Aletras AH, Hsu LY, Arai AE, Radiology 2005 236 859 866 10.1148/radiol.2363040413 16118166 (Pubitemid 41170848)
8. MR contrast media for myocardial viability, microvascular integrity and perfusion. Saeed M, Wendland MF, Watzinger N, Akbari H, Higgins CB, Eur J Radiol 2000 34 179 195 10.1016/S0720-048X(00)00198-4 10927160 (Pubitemid 30601692)
9. Normal and infarcted myocardium: differentiation with cellular uptake of manganese at MR imaging in a rat model. Bremerich J, Saeed M, Arheden H, Higgins CB, Wendland MF, Radiology 2000 216 524 530 10924581 (Pubitemid 30599877)
10. Safety and efficacy of mangafodipir trisodium (MnDPDP) injection for hepatic MRI in adults: results of the U.S. multicenter phase III clinical trials (safety). Federle MP, Chezmar JL, Rubin DL, Weinreb JC, Freeny PC, Semelka RC, Brown JJ, Borello JA, Lee JK, Mattrey R, et al. J Magn Reson Imaging 2000 12 186 197 10.1002/1522-2586(200007)12:1<186::AID-JMRI21>3.0.CO;2-2 10931579 (Pubitemid 30437278)
11. Cardiovascular toxicity and tissue proton T1 response to manganese injection in the dog and rabbit. Wolf GL, Baum L, AJR Am J Roentgenol 1983 141 193 197 6305179 (Pubitemid 13063905)
12. Efficacy and safety of mangafodipir trisodium (MnDPDP) injection for hepatic MRI in adults: results of the U.S. Multicenter phase III clinical trials. Efficacy of early imaging. Federle M, Chezmar J, Rubin DL, Weinreb J, Freeny P, Schmiedl UP, Brown JJ, Borrello JA, Lee JK, Semelka RC, et al. J Magn Reson Imaging 2000 12 689 701 10.1002/1522-2586(200011)12:5<689::AID- JMRI5>3.0.CO;2-Z 11050638
13. Hemodynamic effects of rapid and slow infusions of manganese chloride and gadolinium-DTPA in dogs. Slutsky RA, Peterson T, Strich G, Brown JJ, Radiology 1985 154 733 735 3969479 (Pubitemid 15162372)
14. Normalized left ventricular systolic and diastolic function by steady state free precession cardiovascular magnetic resonance. Maceira AM, Prasad SK, Khan M, Pennell DJ, J Cardiovasc Magn Reson 2006 8 417 426 10.1080/ 10976640600572889 16755827
15. A comparison of two methods for measuring the signal to noise ratio on MR images. Firbank MJ, Coulthard A, Harrison RM, Williams ED, Phys Med Biol 1999 44 261 264 10.1088/0031-9155/44/12/403 10616158
16. Inversion recovery TrueFISP: quantification of T(1), T(2), and spin density. Schmitt P, Griswold MA, Jakob PM, Kotas M, Gulani V, Flentje M, Haase A, Magn Reson Med 2004 51 661 667 10.1002/mrm.20058 15065237 (Pubitemid 38420441)
17. Characterization of viable and nonviable myocardium at MR imaging: comparison of gadolinium-based extracellular and blood pool contrast materials versus manganese-based contrast materials in a rat myocardial infarction model. Flacke S, Allen JS, Chia JM, Wible JH, Periasamy MP, Adams MD, Adzamli IK, Lorenz CH, Radiology 2003 226 731 738 10.1148/radiol.2263020151 12601183 (Pubitemid 36259149)
18. Manganese enhanced magnetic resonance imaging of normal and ischemic canine heart. Hu TC, Christian TF, Aletras AH, Taylor JL, Koretsky AP, Arai AE, Magn Reson Med 2005 54 196 200 10.1002/mrm.20516 15968667 (Pubitemid 40898413)
19. Studies on manganese. 3. The biological half-life of radiomanganese in man and factors which affect this half-life. Mahoney JP, Small WJ, J Clin Invest 1968 47 643 653 5637148
20. The partition of manganese among organs and intracellular organelles of the rat. Maynard LS, Cotzias GC, J Biol Chem 1955 214 489 495 14367406
21. Thallium-like test for myocardial viability with MnDPDP-enhanced MRI. Wendland MF, Saeed M, Bremerich J, Arheden H, Higgins CB, Acad Radiol 2002 9 Suppl 1 82 83 10.1016/S1076-6332(03)80405-1 12019904 (Pubitemid 34441450)
22. Proton nuclear magnetic resonance imaging of regionally ischemic canine hearts: effect of paramagnetic proton signal enhancement. Brady TJ, Goldman MR, Pykett IL, Buonanno FS, Kistler JP, Newhouse JH, Burt CT, Hinshaw WS, Pohost GM, Radiology 1982 144 343 347 6283594 (Pubitemid 12096459)
23. Contrast enhanced MRI of stunned myocardium using Mn-based MRI contrast media. Wendland MF, Krombach GA, Higgins CB, Novikov V, Saeed M, Acad Radiol 2002 9 Suppl 2 341 342 10.1016/S1076-6332(03)80224-6 12188269 (Pubitemid 34857715)
24. Manganese-enhanced MRI of mouse heart during changes in inotropy. Hu TC, Pautler RG, MacGowan GA, Koretsky AP, Magn Reson Med 2001 46 884 890 10.1002/mrm.1273 11675639 (Pubitemid 33019911)
25. Dobutamine-induced stress affects intracellular uptake of manganese: a quantitative magnetic resonance imaging study in pigs. Eriksson R, Johansson L, Bjerner T, Ahlstrom H, J Magn Reson Imaging 2005 21 360 364 10.1002/jmri.20279 15779028 (Pubitemid 40446429)
26. Magnetic resonance imaging of myocardial infarction using a manganese-based contrast agent (EVP 1001-1): preliminary results in a dog model. Storey P, Chen Q, Li W, Seoane PR, Harnish PP, Fogelson L, Harris KR, Prasad PV, J Magn Reson Imaging 2006 23 228 234 10.1002/jmri.20500 16416440 (Pubitemid 43191079)
27. Preliminary evaluation of EVP 1001-1: a new cardiac-specific magnetic resonance contrast agent with kinetics suitable for steady-state imaging of the ischemic heart. Storey P, Danias PG, Post M, Li W, Seoane PR, Harnish PP, Edelman RR, Prasad PV, Invest Radiol 2003 38 642 652 10.1097/01.rli.0000077057. 88108.3f 14501492 (Pubitemid 37140287)
28. Manganese dipyridoxyl-diphosphate (MnDPDP) as a viability marker in patients with myocardial infarction. Skjold A, Amundsen BH, Wiseth R, Stoylen A, Haraldseth O, Larsson HB, Jynge P, J Magn Reson Imaging 2007 26 720 727 10.1002/jmri.21065 17729351 (Pubitemid 350194598)
29. An apparent unidirectional influx constant for manganese as a measure of myocardial calcium channel activity. Skjold A, Kristoffersen A, Vangberg TR, Haraldseth O, Jynge P, Larsson HB, J Magn Reson Imaging 2006 24 1047 1055 10.1002/jmri.20736 17024667 (Pubitemid 44658242)
30. Relaxation enhancing properties of MnDPDP in human myocardium. Skjold A, Vangberg TR, Kristoffersen A, Haraldseth O, Jynge P, Larsson HB, J Magn Reson Imaging 2004 20 948 952 10.1002/jmri.20200 15558550 (Pubitemid 39577895)
31. Neurotoxic effects of low level exposure to manganese in human populations. Mergler D, Environ Res 1999 80 99 102 10.1006/enrs.1998.3902 10092399 (Pubitemid 29143254)
32. A Parkinsonian syndrome in methcathinone users and the role of manganese. Stepens A, Logina I, Liguts V, Aldins P, Eksteina I, Platkajis A, Martinsone I, Terauds E, Rozentale B, Donaghy M, N Engl J Med 2008 358 1009 1017 10.1056/NEJMoa072488 18322282 (Pubitemid 351347100)
33. Manganese intoxication and parenteral nutrition. Dickerson RN, Nutrition 2001 17 689 693 10.1016/S0899-9007(01)00546-9 11448607 (Pubitemid 32633818)
34. Manganese-induced parkinsonism and Parkinson's disease. Olanow CW, Ann N Y Acad Sci 2004 1012 209 223 10.1196/annals.1306.018 15105268 (Pubitemid 38453527)
35. Applications of manganese-enhanced magnetic resonance imaging (MEMRI) to imaging of the heart. Wendland MF, NMR Biomed 2004 17 581 594 10.1002/nbm.943 15761947 (Pubitemid 40124783)