Combined drug screening and confirmation by liquid chromatography time-of-flight mass spectrometry with reverse database search

Analytical and Bioanalytical Chemistry

Volumn 403, Issue 5, 2012, Pages 1265-1278

  De Castro, Ana ^a,b   Gergov, Merja ^c   Östman, Pekka ^c   Ojanperä, Ilkka ^c   Pelander, Anna ^c  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^b Research Department Cienytech   (Spain)

^c UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Confirmation; Drug screening; Identification; LC TOFMS

Indexed keywords

ACCURATE MASS; ANALYTES; ANALYTICAL TOXICOLOGY; COLLISION-INDUCED DISSOCIATION; CONFIDENCE LEVELS; CONFIRMATION; DATABASE SEARCHES; DRUG SCREENING; FALSE NEGATIVES; IDENTIFICATION POINT; ION TRAPS; ISOTOPIC PATTERN; LC-TOFMS; LOW CONCENTRATION LEVELS; MOLECULAR FORMULAE; PROTONATED MOLECULES; REPRESENTATIVE COMPOUND; RETENTION TIME; SCREENING METHODS; TARGET DATABASE; TIME OF FLIGHT MASS SPECTROMETRY; URINE SAMPLE;

DATABASE SYSTEMS; IDENTIFICATION (CONTROL SYSTEMS); INFORMATION RETRIEVAL; LIQUID CHROMATOGRAPHY; MASS SPECTROMETERS; MASS SPECTROMETRY; SEARCH ENGINES;

IONS;

DRUG;

ARTICLE; DRUG SCREENING; EVALUATION; FACTUAL DATABASE; HUMAN; LIQUID CHROMATOGRAPHY; METHODOLOGY; URINE;

CHROMATOGRAPHY, LIQUID; DATABASES, FACTUAL; DRUG EVALUATION, PRECLINICAL; HUMANS; PHARMACEUTICAL PREPARATIONS;

EID: 84861230375     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-012-5889-7     Document Type: Article

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