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Volumn 33, Issue 22, 2012, Pages 5534-5540

Enzymatic degradation of heparin-modified hydrogels and its effect on bioactivity

Author keywords

Degradation; Enzyme; Growth factors; Heparanase; Heparin; Hydrogel

Indexed keywords

ANTI-COAGULATION; ANTICOAGULATION PROPERTIES; BLOOD CLOT FORMATION; BLOOD PRODUCTS; CELL RECEPTORS; DUAL EFFECT; ENZYMATIC DEGRADATION; EXTRACELLULAR MATRICES; GROWTH FACTOR; HEPARAN SULFATES; HEPARANASE; HEPARIN; TISSUE REPAIR; TISSUE-ENGINEERED SCAFFOLDS;

EID: 84861225159     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.04.022     Document Type: Article
Times cited : (21)

References (39)
  • 1
    • 23044444804 scopus 로고    scopus 로고
    • Heparan sulfate: a complex polymer charged with biological activity
    • Whitelock J.M., Iozzo R.V. Heparan sulfate: a complex polymer charged with biological activity. Chem Rev 2005, 105:2745-2764.
    • (2005) Chem Rev , vol.105 , pp. 2745-2764
    • Whitelock, J.M.1    Iozzo, R.V.2
  • 2
    • 20144376911 scopus 로고    scopus 로고
    • Identification and characterization of heparin/heparan sulfate binding domains of the endoglycosidase heparanase
    • Levy-Adam F., Abboud-Jarrous G., Guerrini M., Beccati D., Vlodavsky I., Ilan N. Identification and characterization of heparin/heparan sulfate binding domains of the endoglycosidase heparanase. J Biol Chem 2005, 280:20457-20466.
    • (2005) J Biol Chem , vol.280 , pp. 20457-20466
    • Levy-Adam, F.1    Abboud-Jarrous, G.2    Guerrini, M.3    Beccati, D.4    Vlodavsky, I.5    Ilan, N.6
  • 3
    • 7944230119 scopus 로고    scopus 로고
    • Heparan sulfate proteoglycans and heparanase - partners in osteolytic tumor growth and metastasis
    • Sanderson R.D., Yang Y., Suva L.J., Kelly T. Heparan sulfate proteoglycans and heparanase - partners in osteolytic tumor growth and metastasis. Matrix Biol 2004, 23:341-352.
    • (2004) Matrix Biol , vol.23 , pp. 341-352
    • Sanderson, R.D.1    Yang, Y.2    Suva, L.J.3    Kelly, T.4
  • 4
    • 1542319836 scopus 로고    scopus 로고
    • Heparanase degrades syndecan-1 and perlecan heparan sulfate: functional implications for tumor cell invasion
    • Reiland J., Sanderson R.D., Waguespack M., Barker S.A., Long R., Carson D.D., et al. Heparanase degrades syndecan-1 and perlecan heparan sulfate: functional implications for tumor cell invasion. J Biol Chem 2004, 279:8047-8055.
    • (2004) J Biol Chem , vol.279 , pp. 8047-8055
    • Reiland, J.1    Sanderson, R.D.2    Waguespack, M.3    Barker, S.A.4    Long, R.5    Carson, D.D.6
  • 5
    • 0021354360 scopus 로고
    • Metastatic melanoma cell heparanase. Characterization of heparan sulfate degradation fragments produced by B16 melanoma endoglucuronidase
    • Nakajima M., Irimura T., Di Ferrante N., Nicolson G.L. Metastatic melanoma cell heparanase. Characterization of heparan sulfate degradation fragments produced by B16 melanoma endoglucuronidase. J Biol Chem 1984, 259:2283-2290.
    • (1984) J Biol Chem , vol.259 , pp. 2283-2290
    • Nakajima, M.1    Irimura, T.2    Di Ferrante, N.3    Nicolson, G.L.4
  • 6
    • 0034937208 scopus 로고    scopus 로고
    • Heparanases: endoglycosidases that degrade heparan sulfate proteoglycans
    • Bame K.J. Heparanases: endoglycosidases that degrade heparan sulfate proteoglycans. Glycobiology 2001, 11:91R-98R.
    • (2001) Glycobiology , vol.11
    • Bame, K.J.1
  • 7
    • 0033028789 scopus 로고    scopus 로고
    • Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis
    • Hulett M.D., Freeman C., Hamdorf B.J., Baker R.T., Harris M.J., Parish C.R. Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis. Nat Med 1999, 5:803-809.
    • (1999) Nat Med , vol.5 , pp. 803-809
    • Hulett, M.D.1    Freeman, C.2    Hamdorf, B.J.3    Baker, R.T.4    Harris, M.J.5    Parish, C.R.6
  • 8
    • 0033057962 scopus 로고    scopus 로고
    • Mammalian heparanase: Gene cloning, expression and function in tumor progression and metastasis
    • Vlodavsky I., Friedmann Y., Elkin M., Aingorn H., Atzmon R., Ishai-Michaeli R., et al. Mammalian heparanase: Gene cloning, expression and function in tumor progression and metastasis. Nat Med 1999, 5:793-802.
    • (1999) Nat Med , vol.5 , pp. 793-802
    • Vlodavsky, I.1    Friedmann, Y.2    Elkin, M.3    Aingorn, H.4    Atzmon, R.5    Ishai-Michaeli, R.6
  • 9
    • 54849436630 scopus 로고    scopus 로고
    • Diverse cell signaling events modulated by perlecan
    • Whitelock J.M., Melrose J., Iozzo R.V. Diverse cell signaling events modulated by perlecan. Biochemistry 2008, 47:11174-11183.
    • (2008) Biochemistry , vol.47 , pp. 11174-11183
    • Whitelock, J.M.1    Melrose, J.2    Iozzo, R.V.3
  • 10
    • 0030018209 scopus 로고    scopus 로고
    • Involvement of heparan sulfate and related molecules in sequestration and growth promoting activity of fibroblast growth factor
    • Vlodavsky I., Miao H.-Q., Medalion B., Danagher P., Ron D. Involvement of heparan sulfate and related molecules in sequestration and growth promoting activity of fibroblast growth factor. Cancer Metastasis Rev 1996, 15:177-186.
    • (1996) Cancer Metastasis Rev , vol.15 , pp. 177-186
    • Vlodavsky, I.1    Miao, H.-Q.2    Medalion, B.3    Danagher, P.4    Ron, D.5
  • 11
    • 0030801592 scopus 로고    scopus 로고
    • A rapid quantitative assay for the detection of mammalian heparanase activity
    • Freeman C., Parish C.R. A rapid quantitative assay for the detection of mammalian heparanase activity. Biochem J 1997, 325:229-237.
    • (1997) Biochem J , vol.325 , pp. 229-237
    • Freeman, C.1    Parish, C.R.2
  • 12
    • 0028916622 scopus 로고
    • Molecular behavior adapts to context: heparanase functions as an extracellular matrix-degrading enzyme or as a T cell adhesion molecule, depending on the local pH
    • Gilat D., Hershkoviz R., Goldkorn I., Cahalon L., Korner G., Vlodavsky I., et al. Molecular behavior adapts to context: heparanase functions as an extracellular matrix-degrading enzyme or as a T cell adhesion molecule, depending on the local pH. J Exp Med 1995, 181:1929-1934.
    • (1995) J Exp Med , vol.181 , pp. 1929-1934
    • Gilat, D.1    Hershkoviz, R.2    Goldkorn, I.3    Cahalon, L.4    Korner, G.5    Vlodavsky, I.6
  • 13
    • 0029555648 scopus 로고
    • Activation of platelet heparitinase by vascular cell lysates
    • Graham L., Hayward I., Underwood P. Activation of platelet heparitinase by vascular cell lysates. Biochem Mol Biol Int 1995, 37:231-237.
    • (1995) Biochem Mol Biol Int , vol.37 , pp. 231-237
    • Graham, L.1    Hayward, I.2    Underwood, P.3
  • 14
    • 0042061223 scopus 로고    scopus 로고
    • Hydrogels for tissue engineering: scaffold design variables and applications
    • Drury J.L., Mooney D.J. Hydrogels for tissue engineering: scaffold design variables and applications. Biomaterials 2003, 24:4337-4351.
    • (2003) Biomaterials , vol.24 , pp. 4337-4351
    • Drury, J.L.1    Mooney, D.J.2
  • 15
    • 4544290851 scopus 로고    scopus 로고
    • Synthesis and characterization of photopolymerized multifunctional hydrogels: Water-soluble poly(vinyl alcohol) and chondroitin sulfate macromers for chondrocyte encapsulation
    • Bryant S.J., Davis-Arehart K.A., Luo N., Shoemaker R.K., Arthur J.A., Anseth K.S. Synthesis and characterization of photopolymerized multifunctional hydrogels: Water-soluble poly(vinyl alcohol) and chondroitin sulfate macromers for chondrocyte encapsulation. Macromolecules 2004, 37:6726-6733.
    • (2004) Macromolecules , vol.37 , pp. 6726-6733
    • Bryant, S.J.1    Davis-Arehart, K.A.2    Luo, N.3    Shoemaker, R.K.4    Arthur, J.A.5    Anseth, K.S.6
  • 17
    • 84937203830 scopus 로고    scopus 로고
    • Degradation of glycosaminoglycans
    • Oxford: Elsevier, J.P. Kamerling (Ed.)
    • Takagaki K., Kakizaki I. Degradation of glycosaminoglycans. Comprehensive glycoscience 2007, 171-192. Oxford: Elsevier. J.P. Kamerling (Ed.).
    • (2007) Comprehensive glycoscience , pp. 171-192
    • Takagaki, K.1    Kakizaki, I.2
  • 18
    • 0029876376 scopus 로고    scopus 로고
    • The degradation of human endothelial cell-derived perlecan and release of bound basic fibroblast growth factor by stromelysin, collagenase, plasmin, and heparanases
    • Whitelock J.M., Murdoch A.D., Iozzo R.V., Underwood P.A. The degradation of human endothelial cell-derived perlecan and release of bound basic fibroblast growth factor by stromelysin, collagenase, plasmin, and heparanases. J Biol Chem 1996, 271:10079-10086.
    • (1996) J Biol Chem , vol.271 , pp. 10079-10086
    • Whitelock, J.M.1    Murdoch, A.D.2    Iozzo, R.V.3    Underwood, P.A.4
  • 19
    • 0025875756 scopus 로고
    • Proteoglycans: Structures and interactions
    • Kjellen L., Lindahl U. Proteoglycans: Structures and interactions. Annu Rev Biochem 1991, 60:443-475.
    • (1991) Annu Rev Biochem , vol.60 , pp. 443-475
    • Kjellen, L.1    Lindahl, U.2
  • 20
    • 53149099301 scopus 로고    scopus 로고
    • Structural and functional characterisation of poly(vinyl alcohol) and heparin hydrogels
    • Nilasaroya A., Poole-Warren L.A., Whitelock J.M., Martens P.J. Structural and functional characterisation of poly(vinyl alcohol) and heparin hydrogels. Biomaterials 2008, 29:4658-4664.
    • (2008) Biomaterials , vol.29 , pp. 4658-4664
    • Nilasaroya, A.1    Poole-Warren, L.A.2    Whitelock, J.M.3    Martens, P.J.4
  • 21
    • 0030001467 scopus 로고    scopus 로고
    • Chemical modifications of heparin that diminish its anticoagulant but preserve its heparanase-inhibitory, angiostatic, anti-tumor and anti-metastatic properties
    • Lapierre F., Holme K., Lam L., Tressler R.J., Storm N., Wee J., et al. Chemical modifications of heparin that diminish its anticoagulant but preserve its heparanase-inhibitory, angiostatic, anti-tumor and anti-metastatic properties. Glycobiology 1996, 6:355-366.
    • (1996) Glycobiology , vol.6 , pp. 355-366
    • Lapierre, F.1    Holme, K.2    Lam, L.3    Tressler, R.J.4    Storm, N.5    Wee, J.6
  • 22
    • 0043123237 scopus 로고    scopus 로고
    • A multiwell format assay for heparanase
    • Behzad F., Brenchley P.E.C. A multiwell format assay for heparanase. Anal Biochem 2003, 320:207-213.
    • (2003) Anal Biochem , vol.320 , pp. 207-213
    • Behzad, F.1    Brenchley, P.E.C.2
  • 23
    • 0022552896 scopus 로고
    • Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue
    • Farndale R.W., Buttle D.J., Barrett A.J. Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue. Biochim Biophys Acta 1986, 883:173-177.
    • (1986) Biochim Biophys Acta , vol.883 , pp. 173-177
    • Farndale, R.W.1    Buttle, D.J.2    Barrett, A.J.3
  • 24
    • 0032850597 scopus 로고    scopus 로고
    • FGF-2/fibroblast growth factor receptor/heparin-like glycosaminoglycan interactions: a compensation model for FGF-2 signaling
    • Padera R., Venkataraman G., Berry D., Godavarti R., Sasisekharan R. FGF-2/fibroblast growth factor receptor/heparin-like glycosaminoglycan interactions: a compensation model for FGF-2 signaling. FASEB J 1999, 13:1677-1687.
    • (1999) FASEB J , vol.13 , pp. 1677-1687
    • Padera, R.1    Venkataraman, G.2    Berry, D.3    Godavarti, R.4    Sasisekharan, R.5
  • 25
    • 0032521630 scopus 로고    scopus 로고
    • Human platelet heparanase: purification, characterization and catalytic activity
    • Freeman C., Parish C.R. Human platelet heparanase: purification, characterization and catalytic activity. Biochem J 1998, 330:1341-1350.
    • (1998) Biochem J , vol.330 , pp. 1341-1350
    • Freeman, C.1    Parish, C.R.2
  • 26
    • 0141618276 scopus 로고    scopus 로고
    • Improved and simple micro assay for sulfated glycosaminoglycans quantification in biological extracts and its use in skin and muscle tissue studies
    • Barbosa I., Garcia S., Barbier-Chassefiere V., Caruelle J.-P., Martelly I., Papy-Garcia D. Improved and simple micro assay for sulfated glycosaminoglycans quantification in biological extracts and its use in skin and muscle tissue studies. Glycobiology 2003, 13:647-653.
    • (2003) Glycobiology , vol.13 , pp. 647-653
    • Barbosa, I.1    Garcia, S.2    Barbier-Chassefiere, V.3    Caruelle, J.-P.4    Martelly, I.5    Papy-Garcia, D.6
  • 28
    • 0032563303 scopus 로고    scopus 로고
    • Substrate specificity of heparanases from human hepatoma and platelets
    • Pikas D.S., Li J.-P., Vlodavsky I., Lindahl U. Substrate specificity of heparanases from human hepatoma and platelets. J Biol Chem 1998, 273:18770-18777.
    • (1998) J Biol Chem , vol.273 , pp. 18770-18777
    • Pikas, D.S.1    Li, J.-P.2    Vlodavsky, I.3    Lindahl, U.4
  • 29
    • 33645983628 scopus 로고    scopus 로고
    • Heparanase neutralizes the anticoagulation properties of heparin and low-molecular-weight heparin
    • Nasser N.J., Sarig G., Brenner B., Nevo E., Goldshmidt O., Zcharia E., et al. Heparanase neutralizes the anticoagulation properties of heparin and low-molecular-weight heparin. J Thromb Haemost 2006, 4:560-565.
    • (2006) J Thromb Haemost , vol.4 , pp. 560-565
    • Nasser, N.J.1    Sarig, G.2    Brenner, B.3    Nevo, E.4    Goldshmidt, O.5    Zcharia, E.6
  • 30
    • 0037837506 scopus 로고    scopus 로고
    • 1976-1983, a critical period in the history of heparin: the discovery of the antithrombin binding site
    • Petitou M., Casu B., Lindahl U. 1976-1983, a critical period in the history of heparin: the discovery of the antithrombin binding site. Biochimie 2003, 85:83-89.
    • (2003) Biochimie , vol.85 , pp. 83-89
    • Petitou, M.1    Casu, B.2    Lindahl, U.3
  • 31
    • 0026727774 scopus 로고
    • Identification of the basic fibroblast growth factor binding sequence in fibroblast heparan sulfate
    • Turnbull J.E., Fernig D.G., Ke Y., Wilkinson M.C., Gallagher J.T. Identification of the basic fibroblast growth factor binding sequence in fibroblast heparan sulfate. J Biol Chem 1992, 267:10337-10341.
    • (1992) J Biol Chem , vol.267 , pp. 10337-10341
    • Turnbull, J.E.1    Fernig, D.G.2    Ke, Y.3    Wilkinson, M.C.4    Gallagher, J.T.5
  • 32
    • 0033532084 scopus 로고    scopus 로고
    • Monomer complexes of basic fibroblast growth factor and heparan sulfate oligosaccharides are the minimal functional unit for cell activation
    • Pye D.A., Gallagher J.T. Monomer complexes of basic fibroblast growth factor and heparan sulfate oligosaccharides are the minimal functional unit for cell activation. J Biol Chem 1999, 274:13456-13461.
    • (1999) J Biol Chem , vol.274 , pp. 13456-13461
    • Pye, D.A.1    Gallagher, J.T.2
  • 33
    • 0027428744 scopus 로고
    • Activating and inhibitory heparin sequences for FGF-2 (basic FGF). Distinct requirements for FGF-1, FGF-2, and FGF-4
    • Guimond S., Maccarana M., Olwin B.B., Lindahl U., Rapraeger A.C. Activating and inhibitory heparin sequences for FGF-2 (basic FGF). Distinct requirements for FGF-1, FGF-2, and FGF-4. J Biol Chem 1993, 268:23906-23914.
    • (1993) J Biol Chem , vol.268 , pp. 23906-23914
    • Guimond, S.1    Maccarana, M.2    Olwin, B.B.3    Lindahl, U.4    Rapraeger, A.C.5
  • 34
    • 4043063680 scopus 로고    scopus 로고
    • The role of perlecan in arterial injury and angiogenesis
    • Segev A., Nili N., Strauss B.H. The role of perlecan in arterial injury and angiogenesis. Cardiovasc Res 2004, 63:603-610.
    • (2004) Cardiovasc Res , vol.63 , pp. 603-610
    • Segev, A.1    Nili, N.2    Strauss, B.H.3
  • 35
    • 45149083078 scopus 로고    scopus 로고
    • Evidence that heparin saccharides promote FGF2 mitogenesis through two distinct mechanisms
    • Goodger S.J., Robinson C.J., Murphy K.J., Gasiunas N., Harmer N.J., Blundell T.L., et al. Evidence that heparin saccharides promote FGF2 mitogenesis through two distinct mechanisms. J Biol Chem 2008, 283:13001-13008.
    • (2008) J Biol Chem , vol.283 , pp. 13001-13008
    • Goodger, S.J.1    Robinson, C.J.2    Murphy, K.J.3    Gasiunas, N.4    Harmer, N.J.5    Blundell, T.L.6
  • 36
    • 0025738740 scopus 로고
    • Comparison of anticoagulant and procoagulant activities of stimulated platelets and platelet-derived microparticles
    • Tans G., Rosing J., Thomassen M., Heeb M., Zwaal R., Griffin J. Comparison of anticoagulant and procoagulant activities of stimulated platelets and platelet-derived microparticles. Blood 1991, 77:2641-2648.
    • (1991) Blood , vol.77 , pp. 2641-2648
    • Tans, G.1    Rosing, J.2    Thomassen, M.3    Heeb, M.4    Zwaal, R.5    Griffin, J.6
  • 37
    • 0019276987 scopus 로고
    • Characterization of platelet endoglycosidase degrading heparin-like polysaccharides
    • Oldberg A., Heldin C.H., Wasteson A., Busch C., Hook M. Characterization of platelet endoglycosidase degrading heparin-like polysaccharides. Biochemistry 1980, 19:5755-5762.
    • (1980) Biochemistry , vol.19 , pp. 5755-5762
    • Oldberg, A.1    Heldin, C.H.2    Wasteson, A.3    Busch, C.4    Hook, M.5
  • 38
    • 0028102255 scopus 로고
    • The biology of perlecan: the multifaceted heparan sulphate proteoglycan of basement membranes and pericellular matrices
    • Iozzo R.V., Cohen I.R., Grässel S., Murdoch A.D. The biology of perlecan: the multifaceted heparan sulphate proteoglycan of basement membranes and pericellular matrices. Biochem J 1994, 302:625-639.
    • (1994) Biochem J , vol.302 , pp. 625-639
    • Iozzo, R.V.1    Cohen, I.R.2    Grässel, S.3    Murdoch, A.D.4
  • 39
    • 0035912864 scopus 로고    scopus 로고
    • Guide to anticoagulant therapy: heparin: a statement for healthcare professionals from the American Heart Association
    • Hirsh J., Anand S.S., Halperin J.L., Fuster V. Guide to anticoagulant therapy: heparin: a statement for healthcare professionals from the American Heart Association. Circulation 2001, 103:2994-3018.
    • (2001) Circulation , vol.103 , pp. 2994-3018
    • Hirsh, J.1    Anand, S.S.2    Halperin, J.L.3    Fuster, V.4


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