Enantiomeric resolution of albendazole sulfoxide by semipreparative HPLC and in vitro study of growth inhibitory effects on human cancer cell lines

Journal of Pharmaceutical and Biomedical Analysis

Volumn 66, Issue , 2012, Pages 100-108

  Belaz, Kátia Roberta A ^a   Denadai, Marina ^a   Almeida, Ana Paula ^b,c   Lima, Raquel T ^b,c   Vasconcelos, M Helena ^b   Pinto, M Madalena ^b,c   Cass, Quezia B ^a   Oliveira, Regina V ^a  

^a FEDERAL UNIVERSITY OF SÃO CARLOS   (Brazil)

^b UNIVERSITY OF PORTO   (Portugal)

^c University of Porto   (Portugal)

Author keywords

Albendazole sulfoxide; Apoptosis; Polysaccharide based chiral stationary phases; Semipreparative enantiomeric separation; Tumor cell lines

Indexed keywords

ALBENDAZOLE SULFONE; ALBENDAZOLE SULFOXIDE; AMYLOSE TRIS(3,5 DIMETHYLPHENYLCARBAMATE); AMYLOSE TRIS[1 PHENYLETHYLCARBAMATE]; CELLULOSE TRIS(3,5 DIMETHYLPHENYLCARBAMATE); METHANOL; POLYSACCHARIDE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BREAST ADENOCARCINOMA; CANCER GROWTH; CANCER INHIBITION; CELL GROWTH; CHEMICAL STRUCTURE; CHIRALITY; CIRCULAR DICHROISM; CONTROLLED STUDY; DRUG EFFECT; DRUG RETENTION; ENANTIOMER; ENANTIOSELECTIVITY; FLOW CYTOMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; LIQUID CHROMATOGRAPHY; LUNG NON SMALL CELL CANCER; MELANOMA; PRIORITY JOURNAL; SCALE UP; SEPARATION TECHNIQUE;

ALBENDAZOLE; ANTHELMINTICS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIRCULAR DICHROISM; HUMANS; NEOPLASMS; OPTICAL ROTATION; STEREOISOMERISM;

EID: 84861222683     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2012.03.012     Document Type: Article

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