Dose-dependent activity of albendazole against benzimidazole-resistant nematodes in sheep: Relationship between pharmacokinetics and efficacy

Experimental Parasitology

Volumn 106, Issue 3-4, 2004, Pages 150-157

  Moreno, L ^a,b   Echevarria, F ^c   Munoz F ^c   Alvarez, L ^a,b   Sanchez Bruni, S ^a,b   Lanusse, C ^a,b  

^a UNIVERSIDAD NACIONAL DEL CENTRO DE LA PROVINCIA DE BUENOS AIRES   (Argentina)

^b Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

^c EMBRAPA CERRADOS   (Brazil)

Author keywords

Albendazole; Benzimidazole anthelmintics; Benzimidazole resistant nematodes; Efficacy; Pharmacokinetics; Sheep nematodes

Indexed keywords

ALBENDAZOLE; ALBENDAZOLE SULFONE; ALBENDAZOLE SULFOXIDE; BENZIMIDAZOLE; DRUG METABOLITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTHELMINTIC ACTIVITY; AREA UNDER THE CURVE; ARTICLE; AUTOPSY; CONTROLLED STUDY; CORRELATION ANALYSIS; DOSE RESPONSE; DRUG ACTIVITY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG EFFICACY; GASTROINTESTINAL INFECTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LOW DRUG DOSE; NEMATODE; NEMATODIASIS; NONHUMAN; PARASITE IDENTIFICATION; PRIORITY JOURNAL; SHEEP; SUSPENSION; THERAPY RESISTANCE; WORM;

ADMINISTRATION, ORAL; ALBENDAZOLE; ANIMALS; ANTHELMINTICS; AREA UNDER CURVE; BENZIMIDAZOLES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE; FECES; INTESTINAL DISEASES, PARASITIC; NEMATODE INFECTIONS; PARASITE EGG COUNT; RANDOM ALLOCATION; SHEEP; SHEEP DISEASES; STRONGYLIDA;

ANIMALIA; NEMATODA; OVIS ARIES;

EID: 2542435938     PISSN: 00144894     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exppara.2004.03.003     Document Type: Article

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