Stimulation of vesicular monoamine transporter 2 activity by DJ-1 in SH-SY5Y cells

Biochemical and Biophysical Research Communications

Volumn 421, Issue 4, 2012, Pages 813-818

  Ishikawa, Shizuma ^a   Tanaka, Yuki ^a   Takahashi Niki, Kazuko ^a   Niki, Takeshi ^a   Ariga, Hiroyoshi ^a   Iguchi Ariga, Sanae M M ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

DJ 1; Dopamine; VMAT2

Indexed keywords

CYSTEINE; MESSENGER RNA; VESICULAR MONOAMINE TRANSPORTER 2;

ARTICLE; CELL LINE; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; ONCOGENE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN LOCALIZATION; SYNAPSE; SYNAPTIC MEMBRANE; SYNTHESIS; WILD TYPE;

CELL LINE; CYSTEINE; GENE KNOCKDOWN TECHNIQUES; HUMANS; IMMUNOPRECIPITATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MUTATION; ONCOGENE PROTEINS; PARKINSON DISEASE; RNA, SMALL INTERFERING; SYNAPSES; TRANSCRIPTIONAL ACTIVATION; VESICULAR MONOAMINE TRANSPORT PROTEINS;

EID: 84861221209     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.04.095     Document Type: Article

References (33)

1. Miller G.W., Staley J.K., Heilman C.J., Perez J.T., Mash D.C., Rye D.B., Levey A.I. Immunochemical analysis of dopamine transporter protein in Parkinson's disease. Ann. Neurol. 1997, 41:530-539.
2. Miller G.W., Erickson J.D., Perez J.T., Penland S.N., Mash D.C., Rye D.B., Levey A.I. Immunochemical analysis of vesicular monoamine transporter (VMAT2) protein in Parkinson's disease. Exp. Neurol. 1999, 156:138-148.
3. Cartier E.A., Parra L.A., Baust T.B., Quiroz M., Salazar G., Faundez V., Egaña L., Torres G.E. A biochemical and functional protein complex involving dopamine synthesis and transport into synaptic vesicles. J. Biol. Chem. 2010, 285:1957-1966.
4. Kitada T., Asakawa S., Hattori N., Matsumine H., Yamamura Y., Minoshima S., Yokochi M., Mizuno Y., Shimizu N. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 1998, 392:605-608.
5. Bonifati V., Rizzu P., van Baren M.J., Schaap O., Breedveld G.J., Krieger E., Dekker M.C., Squitieri F., Ibanez P., Joosse M., van Dongen J.W., Vanacore N., van Swieten J.C., Brice A., Meco G., van Duijn C.M., Oostra B.A., Heutink P. Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science 2003, 299:256-259.
6. Valente E.M., Abou-Sleiman P.M., Caputo V., Muqit M.M., Harve K., Gispert S., Ali Z., Del Turco D., Bentivoglio A.R., Healy D.G., Albanese A., Nussbaum R., González-Maldonado R., Deller T., Salvi S., Cortelli P., Gilks W.P., Latchman D.S., Harvey R.J., Dallapiccola B., Auburger G., Wood N.W. Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science 2004, 304:1158-1160.
7. Nagakubo D., Taira T., Kitaura H., Ikeda M., Tamai K., Iguchi-Ariga S.M.M., Ariga H. DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras. Biochem. Biophys. Res. Commum. 1997, 231:509-513.
8. Takahashi K., Taira T., Niki T., Seino C., Iguchi-Ariga S.M.M., Ariga H. DJ-1 positively regulates the androgen receptor by impairing the binding of PIASx alpha to the receptor. J. Biol. Chem. 2001, 276:37556-37563.
9. Niki T., Takahashi-Niki K., Taira T., Iguchi-Ariga S.M.M., Ariga H. DJBP: a novel DJ-1-binding protein, negatively regulates the androgen receptor by recruiting histone deacetylase complex, and DJ-1 antagonizes this inhibition by abrogation of this complex. Mol. Cancer Res. 2003, 1:247-261.
10. Zhong N., Kim C.Y., Rizzu P., Geula C., Porter D.R., Pothos E.N., Squitieri F., Heutink P., Xu J. DJ-1 transcriptionally up-regulates the human tyrosine hydroxylase by inhibiting the sumoylation of pyrimidine tract-binding protein-associated splicing factor. J. Biol. Chem. 2006, 281:20940-20948.
11. Clements C.M., McNally R.S., Conti B.J., Mak T.W., Ting J.P. DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2. Proc. Natl. Acad. Sci. USA 2006, 103:15091-15096.
12. Tillman J.E., Yuan J., Gu G., Fazli L., Ghosh R., Flynt A.S., Gleave M., Rennie P.S., Kasper S. DJ-1 binds androgen receptor directly and mediates its activity in hormonally treated prostate cancer cells. Cancer Res. 2007, 67:4630-4637.
13. Fan J., Ren H., Jia N., Fei E., Zhou T., Jiang P., Wu M., Wang G. DJ-1 decreases Bax expression through repressing p53 transcriptional activity. J. Biol. Chem. 2008, 283:4022-4030.
14. Xu J., Zhong N., Wang H., Elias J.E., Kim C.Y., Woldman I., Pifl C., Gygi S.P., Geula C., Yankner B.A. The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis. Hum. Mol. Genet. 2005, 14:1231-1241.
15. Ishikawa S., Taira T., Takahashi-Niki K., Niki T., Ariga H., Iguchi-Ariga S.M.M. Human DJ-1-specific transcriptional activation of tyrosine hydroxylase gene. J. Biol. Chem. 2010, 285:39718-39731.
16. Shinbo Y., Taira T., Niki T., Iguchi-Ariga S.M.M., Ariga H. DJ-1 restores p53 transcription activity inhibited by Topors/p53BP3. Int. J. Oncol. 2005, 26:641-648.
17. Kim R.H., Peters M., Jang Y., Shi W., Pintilie M., Fletcher G.C., DeLuca C., Liepa J., Zhou L., Snow B., Binari R.C., Manoukian A.S., Bray M.R., Liu F.F., Tsao M.S., Mak T.W. DJ-1, a novel regulator of the tumor suppressor PTEN. Cancer Cell 2005, 7:263-273.
18. Junn E., Taniguchi H., Jeong B.S., Zhao X., Ichijo H., Mouradian M.M. Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death. Proc. Natl. Acad. Sci. USA 2005, 102:9691-9696.
19. Lev N., Ickowicz D., Barhum Y., Lev S., Melamed E., Offen D. DJ-1 protects against dopamine toxicity. J. Neural Transm. 2009, 116:151-160.
20. Aron L., Klein P., Pham T.T., Kramer E.R., Wurst W., Klein R. Pro-survival role for Parkinson's associated gene DJ-1 revealed in trophically impaired dopaminergic neurons. PLoS Biol. 2010, 8:e1000349.
21. Taira T., Saito Y., Niki T., Iguchi-Ariga S.M.M., Takahashi K., Ariga H. DJ-1 has a role in antioxidative stress to prevent cell death. EMBO Rep. 2004, 5:213-218.
22. Canet-Aviles R.M., Wilson M.A., Miller D.W., Ahmad R., McLendon C., Bandyopadhyay S., Baptista M.J., Ringe D., Petsko G.A., Cookson M.R. The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization. Proc. Natl. Acad. Sci. USA 2004, 101:9103-9108.
23. Martinat C., Shendelman S., Jonason A., Leete T., Beal M.F., Yang L., Floss T., Abeliovich A. Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: an ES- derived cell model of primary Parkinsonism. PLoS Biol. 2004, 2:e327.
24. Ishikawa S., Taira T., Niki T., Takahashi-Niki K., Maita C., Maita H., Ariga H., Iguchi-Ariga S.M.M. Oxidative status of DJ-1-dependent activation of dopamine synthesis through interaction of tyrosine hydroxylase and 4-dihydroxy-L-phenylalanine (L-DOPA) decarboxylase with DJ-1. J. Biol. Chem. 2009, 284:28832-28844.
25. Zhang L., Shimoji M., Thomas B., Moore D.J., Yu S.W., Marupudi N.I., Torp R., Torgner I.A., Ottersen O.P., Dawson T.M., Dawson V.L. Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis. Hum. Mol. Genet. 2005, 14:2063-2073.
26. Li H.M., Niki T., Taira T., Iguchi-Ariga S.M.M., Ariga H. Association of DJ-1 with chaperones and enhanced association and colocalization with mitochondrial Hsp70 by oxidative stress. Free Radic. Res. 2005, 39:1091-1099.
27. Junn E., Jang W.H., Zhao X., Jeong B.S., Mouradian M.M. Mitochondrial localization of DJ-1 leads to enhanced neuroprotection. J. Neurosci. Res. 2009, 87:123-129.
28. Usami Y., Hatano T., Imai S., Kubo S., Sato S., Saiki S., Fujioka Y., Ohba Y., Sato F., Funayama M., Eguchi H., Shiba K., Ariga H., Shen J., Hattori N. DJ-1 associates with synaptic membranes. Neurobiol. Dis. 2011, 43:651-662.
29. Abou-Sleiman P.M., Healy D.G., Quinn N., Lees A.J., Wood N.W. The role of pathogenic DJ-1 mutations in Parkinson's disease. Ann. Neurol. 2003, 54:283-286.
30. Guillot T.S., Miller G.W. Protective actions of the vesicular monoamine transporter 2 (VMAT2) in monoaminergic neurons. Mol. Neurobiol. 2009, 39:149-170.
31. Harrington K.A., Augood S.J., Kingsbury A.E., Foster O.J., Emson P.C. Dopamine transporter (Dat) and synaptic vesicle amine transporter (VMAT2) gene expression in the substantia nigra of control and Parkinson's disease. Brain Res. Mol. Brain Res. 1996, 36:157-162.
32. Kitada T., Tong Y., Gautier C.A., Shen J. Absence of nigral degeneration in aged parkin/DJ-1/PINK1 triple knockout mice. J. Neurochem. 2009, 111:696-702.
33. Chen L., Cagniard B., Mathews T., Jones S., Koh H.C., Ding Y., Carvey P.M., Ling Z., Kang U.J., Zhuang X. Age-dependent motor deficits and dopaminergic dysfunction in DJ-1 null mice. J. Biol. Chem. 2005, 280:21418-21426.