Modeling of the N-glycosylated transferrin receptor suggests how transferrin binding can occur within the surface coat of trypanosoma brucei

PLoS Pathogens

Volumn 8, Issue 4, 2012, Pages

  Mehlert, Angela ^a   Wormald, Mark R ^b   Ferguson, Michael A J ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EXPRESSION SITE ASSOCIATED GENE 6; EXPRESSION SITE ASSOCIATED GENE 7; GLYCOPEPTIDASE; LECTIN; MANNOSE OLIGOSACCHARIDE; OLIGOSACCHARIDE; PAUCIMANNOSE; TRANSFERRIN RECEPTOR; UNCLASSIFIED DRUG; N ACETYLGLUCOSAMINE; PROTOZOAL PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD FLOW; CONTROLLED STUDY; ENDOCYTOSIS; GLYCOSYLATION; ISOTOPE LABELING; MOLECULAR MODEL; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN BINDING; PROTEIN STRUCTURE; RAT; TRYPANOSOMA; TRYPANOSOMA BRUCEI; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; METABOLISM; PROTEIN QUATERNARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; STRUCTURE ACTIVITY RELATION;

TRYPANOSOMA BRUCEI;

ACETYLGLUCOSAMINE; ANIMALS; GLYCOSYLATION; HUMANS; MODELS, MOLECULAR; OLIGOSACCHARIDES; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; PROTOZOAN PROTEINS; RECEPTORS, TRANSFERRIN; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOSOMA BRUCEI BRUCEI;

EID: 84861203634     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002618     Document Type: Article

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