Mitogenic and anti-apoptotic effects of insulin in endometrial cancer are phosphatidylinositol 3-kinase/Akt dependent

Gynecologic Oncology

Volumn 125, Issue 3, 2012, Pages 734-741

  Wang, Yingmei ^a   Hua, Shaofang ^b   Tian, Wenyan ^a   Zhang, Lizhi ^c   Zhao, Jing ^a   Zhang, Huiying ^a   Zhang, Wei ^d   Xue, Fengxia ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

^b SECOND HOSPITAL OF TIANJIN MEDICAL UNIVERSITY   (China)

^c TIANJIN FIRST CENTRAL HOSPITAL   (China)

^d UNIVERSITY OF TEXAS   (United States)

Author keywords

Apoptosis; Endometrial cancer; Insulin; Insulin receptor; PI3K Akt pathway; Proliferation

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; BROXURIDINE; INSULIN; LIPOCORTIN 5; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

APOPTOSIS; CANCER CELL; CANCER INVASION; CELL PROLIFERATION; CONFERENCE PAPER; CONTROLLED STUDY; DISEASE SEVERITY; ENDOMETRIUM CANCER; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FEMALE; HUMAN; HUMAN CELL; INSULIN BLOOD LEVEL; LYMPH NODE METASTASIS; MITOGENESIS; MYOMETRIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RADIOIMMUNOASSAY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

APOPTOSIS; CELL LINE, TUMOR; ENDOMETRIAL HYPERPLASIA; ENDOMETRIAL NEOPLASMS; FASTING; FEMALE; HUMANS; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, INSULIN;

EID: 84861202836     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2012.03.012     Document Type: Conference Paper

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