Pharmacokinetic behavior of argirein, derived from rhein, is characterized as slow release and prolonged T 1/2 of rhein in rats

European Journal of Pharmaceutical Sciences

Volumn 46, Issue 5, 2012, Pages 468-474

  Cong, Xiao Dong ^a   Fu, Peng Rong ^a   Dai, De Zai ^b   Zhang, Yun ^a   Dai, Yin ^b  

^a ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

^b CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Argirein; Bioavailability; HPLC; Pharmacokinetic; Rat; Rhein

Indexed keywords

ARGIREIN; PLANT MEDICINAL PRODUCT; RHEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; DRUG BIOAVAILABILITY; DRUG RELEASE; FEMALE; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TIME TO MAXIMUM PLASMA CONCENTRATION;

ADMINISTRATION, ORAL; ANIMALS; ANTHRAQUINONES; ANTI-INFLAMMATORY AGENTS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, REVERSE-PHASE; DELAYED-ACTION PREPARATIONS; FEMALE; HALF-LIFE; INJECTIONS, INTRAVENOUS; MALE; METABOLIC CLEARANCE RATE; PRODRUGS; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS;

EID: 84861197498     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2012.03.014     Document Type: Article

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