Glutathione-mediated neuroprotection against methylmercury neurotoxicity in cortical culture is dependent on MRP1

NeuroToxicology

Volumn 33, Issue 3, 2012, Pages 476-481

  Rush, Travis ^a   Liu, XiaoQian ^a   Nowakowski, Andrew B ^b   Petering, David H ^b   Lobner, Doug ^a  

^a MARQUETTE UNIVERSITY   (United States)

^b UNIVERSITY OF WISCONSIN MILWAUKEE   (United States)

Author keywords

Glutathione; Methylmercury; MRP1; Neuroprotection; Neurotoxicity; System x c

Indexed keywords

CARBON 14; CYCLOHEXIMIDE; CYSTINE; DICHLORODIHYDROFLUORESCEIN; GLUTATHIONE; GLUTATHIONE ETHYL ESTER; METHYLMERCURY; MULTIDRUG RESISTANCE PROTEIN 1; REACTIVE OXYGEN METABOLITE; TROLOX C;

AMINO ACID TRANSPORT; ANIMAL CELL; ARTICLE; CELL LEVEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; FETUS; FLUORESCENCE; GLIA CELL; MIXED CELL CULTURE; MOUSE; NERVE CELL; NERVE CELL CULTURE; NERVE CELL NECROSIS; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN FUNCTION; UPREGULATION;

AMINO ACID TRANSPORT SYSTEM Y+; ANIMALS; CELL DEATH; CELLS, CULTURED; CEREBRAL CORTEX; CYSTINE; CYTOPROTECTION; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FREE RADICAL SCAVENGERS; GLUTATHIONE; MERCURY POISONING, NERVOUS SYSTEM; METHYLMERCURY COMPOUNDS; MICE; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PROTEIN SYNTHESIS INHIBITORS; REACTIVE OXYGEN SPECIES; TIME FACTORS;

EID: 84861196664     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2012.03.004     Document Type: Article

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