Structural role of the active-site metal in the conformation of Trypanosoma brucei phosphoglycerate mutase

FEBS Journal

Volumn 279, Issue 11, 2012, Pages 2012-2021

  Mercaldi, Gustavo F ^a   Pereira, Humberto M ^a   Cordeiro, Artur T ^a   Michels, Paul A M ^b   Thiemann, Otavio H ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b DE DUVE INSTITUTE   (Belgium)

Author keywords

catallytic metal; gluconeogenic pathway; glycolytic pathway; phosphoglycerate mutase; Trypanosoma brucei

Indexed keywords

ALANINE; APOENZYME; ASPARTIC ACID; PHOSPHOGLYCERATE MUTASE; RECOMBINANT PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME STRUCTURE; LEISHMANIA MEXICANA; METAL BINDING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN STRUCTURE; SITE DIRECTED MUTAGENESIS; TRYPANOSOMA BRUCEI; X RAY CRYSTALLOGRAPHY;

ALANINE; AMINO ACID SEQUENCE; APOENZYMES; ASPARTIC ACID; CATALYTIC DOMAIN; CATIONS, DIVALENT; COBALT; CRYSTALLOGRAPHY, X-RAY; KINETICS; LEISHMANIA MEXICANA; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHOSPHOGLYCERATE MUTASE; PROTEIN STRUCTURE, SECONDARY; PROTOZOAN PROTEINS; RECOMBINANT PROTEINS; SCATTERING, SMALL ANGLE; STRUCTURAL HOMOLOGY, PROTEIN; TRYPANOSOMA BRUCEI BRUCEI; X-RAY DIFFRACTION;

LEISHMANIA MEXICANA; TRYPANOSOMA BRUCEI;

EID: 84861196584     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2012.08586.x     Document Type: Article

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