Reversal of slow growth and heartbeat through the restoration of mitochondrial function in clk-1-deficient mouse embryos by exogenous administration of coenzyme Q 10

Experimental Gerontology

Volumn 47, Issue 6, 2012, Pages 425-431

  Takahashi, Mayumi ^a   Shimizu, Takahiko ^a   Shirasawa, Takuji ^b  

^a TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^b JUNTENDO UNIVERSITY   (Japan)

Author keywords

Clk 1 coq7; Coenzyme Q; Growth and heart rates; Mitochondrial function; Mouse embryo

Indexed keywords

ADENOSINE TRIPHOSPHATE; UBIDECARENONE;

APOPTOSIS; ARTICLE; CAENORHABDITIS ELEGANS; CELL GROWTH; CONTROLLED STUDY; EMBRYO; FEMALE; GROWTH CURVE; HEART BEAT; HEART MUSCLE CELL; HEART RATE; LETHALITY; LIFESPAN; LONGEVITY; MALE; MEMBRANE POTENTIAL; MITOCHONDRION; MOUSE; NONHUMAN; ORTHOLOGY; PHENOTYPE; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATE; ANIMALS; APOPTOSIS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; FETAL HEART; HEART RATE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, KNOCKOUT; MITOCHONDRIA; MYOCYTES, CARDIAC; ORGAN CULTURE TECHNIQUES; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; UBIQUINONE; VITAMINS;

BOVINAE; CAENORHABDITIS ELEGANS; MAMMALIA; MUS; SCHIZOSACCHAROMYCETACEAE;

EID: 84861194019     PISSN: 05315565     EISSN: 18736815     Source Type: Journal    
DOI: 10.1016/j.exger.2012.03.008     Document Type: Article

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