Mouse coq7/clk-1 orthologue rescued slowed rhythmic behavior and extended life span of clk-1 longevity mutant in Caenorhabditis elegans

Biochemical and Biophysical Research Communications

Volumn 286, Issue 3, 2001, Pages 534-540

  Takahashi, Mayumi ^a   Asaumi, Sunao ^a   Honda, Shuji ^a   Suzuki, Yo ichi ^a   Nakai, Daisuke ^a   Kuroyanagi, Hidehito ^a   Shimizu, Takahiko ^a   Honda, Yoko ^a   Shirasawa, Takuji ^a  

^a TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

Author keywords

Caenorhabditis elegans; Coq7 clk 1; Life span; Longevity; Mitochondria; Mouse; Rhythm; Ubiquinone

Indexed keywords

UBIQUINONE;

ARTICLE; BIOLOGICAL RHYTHM; CAENORHABDITIS ELEGANS; CHEMICAL ANALYSIS; CONTROLLED STUDY; DEFECATION; GENE CONTROL; GENE COQ7; GENE EXPRESSION; GENE MUTATION; LIFESPAN; LONGEVITY; MITOCHONDRIAL RESPIRATION; MOUSE; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY; TISSUE DISTRIBUTION; TRANSGENIC MOUSE;

CAENORHABDITIS ELEGANS; MAMMALIA; SACCHAROMYCES CEREVISIAE;

EID: 0034801834     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2001.5439     Document Type: Article

References (23)

1. Molecular genetics of life span in C. elegans: How much does it teach us?
2. daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans
3. A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans
4. Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1
5. A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes
6. Oxidative stress, caloric restriction, and aging
7. Mutations in the clk-1 gene of Caenorhabditis elegans affect developmental and behavioral timing
8. Orthologues of the Caenorhabditis elegans longevity gene clk-1 in mouse and human
9. Conservation of the Caenorhabditis elegans timing gene clk-1 from yeast to human: A gene required for ubiquinone biosynthesis with potential implications for aging
10. Altered quinone biosynthesis in the long-lived clk-1 mutants of Caenorhabditis elegans
11. A dietary source of coenzyme Q is essential for growth of long-lived Caenorhabditis elegans clk-1 mutants
12. CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans
13. Apparent uncoupling of energy production and consumption in long-lived Clk mutants of Caenorhabditis elegans
14. DNA transformation
15. A mouse serine/threonine kinase homologous to C. elegans UNC51 functions in parallel fiber formation of cerebellar granule neurons
16. The genetics of Caenorhabditis elegans
17. Methods
18. A knowledge base for predicting protein localization sites in eukaryotic cells
19. Yeast Clk-1 homologue (Coq7/Cat5) is a mitochondrial protein in coenzyme Q synthesis
20. Mouse CLK-1 is imported into mitochondria by an unusual process that requires a leader sequence but no membrane potential
21. Circadian and ultradian clock-controlled rhythms in unicellular microorganisms